{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T23:59:57Z","timestamp":1782950397671,"version":"3.54.5"},"reference-count":17,"publisher":"International College of Surgeons","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:p>Malignant phyllodes tumors are an uncommon breast tumor in clinical practice of surgery. The study population consisted of five consecutive patients. Each patient had complete clinical follow-up with annual mammograms and physical examination in a specialized breast clinic. They were surgically treated for with malignant phyllodes tumor of the breast. All patients are alive and well with a complete follow-up. The first 2 patients had a fine needle aspiration cytology and were surgically treated by a simple mastectomy. The remaining 3 patients were preoperatively diagnosed with core needle biopsy. These 3 patients were treated with a wide excision of the phyllodes tumor with at least a 1-cm margin of normal breast tissue. Mammography was 100% accurate in demonstrating a dense breast mass. In each patient ultrasound suggested heterogeneous internal echoes present in each malignant phyllodes tumor. Fine needle aspiration cytology was of no value in the diagnosis of a phyllodes tumor. Core needle biopsy is highly reliable in establishing a preoperative diagnosis. The most helpful clinical observation of a malignant phyllodes tumor was rapid growth and enlargement, which is frequently noted by the patient.<\/jats:p>","DOI":"10.9738\/cc79.1","type":"journal-article","created":{"date-parts":[[2012,10,25]],"date-time":"2012-10-25T15:57:41Z","timestamp":1351180661000},"page":"95-98","source":"Crossref","is-referenced-by-count":15,"title":["Malignant Phyllodes Tumors of the Breast: A Study in Clinical Practice"],"prefix":"10.9738","volume":"97","author":[{"given":"James","family":"Majeski","sequence":"first","affiliation":[{"name":"The Majeski Surgical Institute, Mt. Pleasant, South Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Stroud","sequence":"additional","affiliation":[{"name":"The Majeski Surgical Institute, Mt. Pleasant, South Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4721","reference":[{"issue":"1","key":"i0020-8868-97-2-95-Foxcroft1","series-title":"Breast","first-page":"27","article-title":"Difficulties in the preoperative diagnosis of phyllodes tumors of the breast.","volume":"16","author":"Foxcroft\n              LM","year":"2007","unstructured":"Foxcroft\n              LM\n            , EvansEB, and PorterAJ. Difficulties in the preoperative diagnosis of phyllodes tumors of the breast.Breast2007. 16 (1):27\u201337."},{"issue":"5","key":"i0020-8868-97-2-95-Tse1","series-title":"Breast Cancer","first-page":"29","article-title":"Phyllodes tumor of the breast: an update.","volume":"17","author":"Tse\n              GMK","year":"2010","unstructured":"Tse\n              GMK\n            , NiuY, and ShiH. Phyllodes tumor of the breast: an update.Breast Cancer2010. 17 (5):29\u201334."},{"issue":"2","key":"i0020-8868-97-2-95-Benhassouna1","series-title":"Am J Surg","first-page":"141","article-title":"Phyllodes tumors of the breast: a case series of 106 patients.","volume":"192","author":"Benhassouna\n              J","year":"2006","unstructured":"Benhassouna\n              J\n            , DamakT, GamoudiA, CharquiR, KhomsiF, MahjoubS, et al. Phyllodes tumors of the breast: a case series of 106 patients.Am J Surg2006. 192 (2):141\u2013147."},{"issue":"7","key":"i0020-8868-97-2-95-Chaney1","series-title":"Cancer","first-page":"1502","article-title":"Primary treatment of cystosarcoma phyllodes of the breast.","volume":"89","author":"Chaney\n              AW","year":"2000","unstructured":"Chaney\n              AW\n            , PollackA, McneeseM, ZagersK, PistersP, PollockRE, et al. Primary treatment of cystosarcoma phyllodes of the breast.Cancer2000. 89 (7):1502\u20131511."},{"issue":"8","key":"i0020-8868-97-2-95-Shabahang1","series-title":"Am Surg","first-page":"673","article-title":"Surgical management of primary breast sarcoma.","volume":"68","author":"Shabahang\n              M","year":"2002","unstructured":"Shabahang\n              M\n            , FrancheschiD, SundaramM, CastilloMH, MoffatFL, FrankDS, et al. Surgical management of primary breast sarcoma.Am Surg2002. 68 (8):673\u2013677."},{"issue":"3","key":"i0020-8868-97-2-95-Stebbing1","series-title":"Ann R Coll Surg Engl","first-page":"181","article-title":"Diagnosis and management of phyllodes tumor of the breast: experience of 33 cases at a specialist center.","volume":"77","author":"Stebbing\n              JF","year":"1995","unstructured":"Stebbing\n              JF\n             and NashAG. Diagnosis and management of phyllodes tumor of the breast: experience of 33 cases at a specialist center.Ann R Coll Surg Engl1995. 77 (3):181\u2013184."},{"issue":"5","key":"i0020-8868-97-2-95-Dillon1","series-title":"Surgery","first-page":"779","article-title":"Needle core biopsy in the diagnosis of phyllodes neoplasm.","volume":"140","author":"Dillon\n              MF","year":"2006","unstructured":"Dillon\n              MF\n            , QuinnCM, McDermottEW, DohertyMB, O'HigginsN, and HillA. Needle core biopsy in the diagnosis of phyllodes neoplasm.Surgery2006. 140 (5):779\u2013784."},{"issue":"7","key":"i0020-8868-97-2-95-Shimizu1","series-title":"Acta Cytol","first-page":"691","article-title":"Cytologic evaluation of phyllodes tumors as compared to fibroadenomas of the breast.","volume":"36","author":"Shimizu\n              K","year":"1994","unstructured":"Shimizu\n              K\n            , MasawaN, and YamadaT. Cytologic evaluation of phyllodes tumors as compared to fibroadenomas of the breast.Acta Cytol1994. 36 (7):691\u2013697."},{"issue":"1","key":"i0020-8868-97-2-95-Gordon1","series-title":"Radiology","first-page":"233","article-title":"Solid breast masses diagnosed as fibroadenomas at fine needle aspiration biopsy: acceptable rates of growth at long term follow-up.","volume":"229","author":"Gordon\n              P","year":"2003","unstructured":"Gordon\n              P\n            , GagnonF, and LanzkowskyL. Solid breast masses diagnosed as fibroadenomas at fine needle aspiration biopsy: acceptable rates of growth at long term follow-up.Radiology2003. 229 (1):233\u2013238."},{"issue":"3","key":"i0020-8868-97-2-95-Lv1","series-title":"Breast Cancer Res Treat","first-page":"411","article-title":"Chromosomal aberrations and genetic relations in benign, borderline, and malignant phyllodes tumors of the breast: a comparative genomic hybridization study.","volume":"112","author":"Lv\n              S","year":"2008","unstructured":"Lv\n              S\n            , NiuY, WeiL, WangX, and ChenY. Chromosomal aberrations and genetic relations in benign, borderline, and malignant phyllodes tumors of the breast: a comparative genomic hybridization study.Breast Cancer Res Treat2008. 112 (3):411\u2013418."},{"issue":"1","key":"i0020-8868-97-2-95-Jee1","series-title":"Anal Cell Pathol","first-page":"89","article-title":"Gain in 1q is a common abnormality in phyllodes tumors of the breast.","volume":"25","author":"Jee\n              KV","year":"2003","unstructured":"Jee\n              KV\n            , GongG, AhnSH, ParkJM, and KnoutilaS. Gain in 1q is a common abnormality in phyllodes tumors of the breast.Anal Cell Pathol2003. 25 (1):89\u201393."},{"issue":"3","key":"i0020-8868-97-2-95-Karim1","series-title":"Breast","first-page":"165","article-title":"Phyllodes tumors of the breast. A clinicopathological analysis of 63 cases from a single institution.","volume":"18","author":"Karim\n              RZ","year":"2009","unstructured":"Karim\n              RZ\n            , GeregaSK, YangYH, SpillaneA, CarmaltH, ScolyerRA, et al. Phyllodes tumors of the breast. A clinicopathological analysis of 63 cases from a single institution.Breast2009. 18 (3):165\u2013170."},{"issue":"1","key":"i0020-8868-97-2-95-Gullett1","series-title":"Breast J","first-page":"41","article-title":"National surgical patterns of care for primary care and axillary staging of phyllodes tumors.","volume":"15","author":"Gullett\n              NP","year":"2009","unstructured":"Gullett\n              NP\n            , RizzoM, and JohnsonPA. National surgical patterns of care for primary care and axillary staging of phyllodes tumors.Breast J2009. 15 (1):41\u201344."},{"issue":"5","key":"i0020-8868-97-2-95-Sahin1","series-title":"The Cancer Bulletin","first-page":"392","article-title":"Phyllodes tumors of the breast.","volume":"47","author":"Sahin\n              AA","year":"1995","unstructured":"Sahin\n              AA\n            , SneigeN, and SingletarySE. Phyllodes tumors of the breast.The Cancer Bulletin1995. 47 (5):392\u2013395."},{"issue":"10","key":"i0020-8868-97-2-95-Barrio1","series-title":"Ann Surg Oncol","first-page":"2961","article-title":"Clinopathologic features and long-term outcomes of 293 phyllodes tumors of the breast.","volume":"14","author":"Barrio\n              AV","year":"2007","unstructured":"Barrio\n              AV\n            , ClarkBD, and GoldbergJI. Clinopathologic features and long-term outcomes of 293 phyllodes tumors of the breast.Ann Surg Oncol2007. 14 (10):2961\u20132970."},{"issue":"4","key":"i0020-8868-97-2-95-Fields1","series-title":"Am J Surg","first-page":"559","article-title":"Treatment and outcomes of patients with primary breast sarcoma.","volume":"196","author":"Fields\n              RC","year":"2008","unstructured":"Fields\n              RC\n            , AftRL, GillandersWE, EberleinTJ, and MargenthalerJA. Treatment and outcomes of patients with primary breast sarcoma.Am J Surg2008. 196 (4):559\u2013561."},{"issue":"4","key":"i0020-8868-97-2-95-Pimiento1","series-title":"J Am Coll Surg","first-page":"537","article-title":"Phyllodes tumors: race-related differences.","volume":"213","author":"Pimiento\n              JM","year":"2011","unstructured":"Pimiento\n              JM\n            , GodgilPV, SantillanAA, LeeMC, EspositoNN, KilukJV, et al. Phyllodes tumors: race-related differences.J Am Coll Surg2011. 213 (4):537\u2013542."}],"container-title":["International Surgery"],"original-title":[],"link":[{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/97\/2\/article-p95.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/international-surgery\/article-pdf\/97\/2\/95\/2213281\/cc79_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/97\/2\/article-p95.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/97\/2\/article-p95.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T19:01:18Z","timestamp":1751482878000},"score":1,"resource":{"primary":{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/97\/2\/article-p95.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":17,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.9738\/cc79.1","relation":{},"ISSN":["0020-8868","2520-2456"],"issn-type":[{"value":"0020-8868","type":"print"},{"value":"2520-2456","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}