{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T19:55:48Z","timestamp":1784058948610,"version":"3.55.0"},"reference-count":35,"publisher":"International College of Surgeons","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:p>The purpose of this study was to analyze the performance of a porcine-derived acellular dermal matrix (Strattice Reconstructive Tissue Matrix) in patients at increased risk for perioperative complications. We reviewed medical records for patients with complex abdominal wall reconstruction (AWR) and Strattice underlay from 2007 to 2010. Intermediate-risk patients were defined as having multiple comorbidities without abdominal infection. Forty-one patients met the inclusion criteria (mean age, 60 years; mean body mass index, 35.5 kg\/m<jats:sup>2<\/jats:sup>). Comorbidities included coronary artery disease (63.4%), diabetes mellitus (36.6%), and chronic obstructive pulmonary disease (17.1%). Fascial closure was achieved in 40 patients (97.6%). Average hospitalization was 6.4 days (range, 1\u201324 days). Complications included seroma (7.3%), wound dehiscence with Strattice exposure (4.9%), cellulitis (2.4%), and hematoma (2.4%). All patients achieved abdominal wall closure with no recurrent hernias or need for Strattice removal. Patients with multiple comorbidities at intermediate risk of postoperative complications can achieve successful, safe AWR with Strattice.<\/jats:p>","DOI":"10.9738\/intsurg-d-13-00053.1","type":"journal-article","created":{"date-parts":[[2013,11,14]],"date-time":"2013-11-14T15:04:38Z","timestamp":1384441478000},"page":"379-384","source":"Crossref","is-referenced-by-count":14,"title":["Critical Analysis of Strattice Performance in Complex Abdominal Wall Reconstruction: Intermediate\u2013Risk Patients and Early Complications"],"prefix":"10.9738","volume":"98","author":[{"given":"Ketan M.","family":"Patel","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, Georgetown University Hospital, Washington, DC 20007"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank P.","family":"Albino","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Georgetown University Hospital, Washington, DC 20007"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice Y.","family":"Nahabedian","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Georgetown University Hospital, Washington, DC 20007"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parag","family":"Bhanot","sequence":"additional","affiliation":[{"name":"Department of Surgery, Georgetown University Hospital, Washington, DC 20007"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4721","reference":[{"issue":"4","key":"i0020-8868-98-4-379-b01","series-title":"Ann Surg","first-page":"578","article-title":"Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia","volume":"240","author":"Burger\n              JW,","year":"2004","unstructured":"Burger\n              JW, \n            \n              Luijendijk\n              RW, \n            \n              Hop\n              WC, \n            \n              Halm\n              JA, \n            \n              Verdaasdonk\n              EG, \n            \n              Jeekel\n              J. \n          \n          Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia. Ann Surg2004;240(4):578\u2013583"},{"issue":"3","key":"i0020-8868-98-4-379-b02","series-title":"Plast Reconstr Surg","first-page":"836","article-title":"Soft polypropylene mesh, but not cadaveric dermis, significantly improves outcomes in midline hernia repairs using the components separation technique","volume":"124","author":"Ko\n              JH,","year":"2009","unstructured":"Ko\n              JH, \n            \n              Salvay\n              DM, \n            \n              Paul\n              BC, \n            \n              Wang\n              EC, \n            \n              Dumanian\n              GA. \n          \n          Soft polypropylene mesh, but not cadaveric dermis, significantly improves outcomes in midline hernia repairs using the components separation technique. Plast Reconstr Surg2009;124(3):836\u2013847"},{"issue":"6","key":"i0020-8868-98-4-379-b03","series-title":"N Engl J Med","first-page":"392","article-title":"A comparison of suture repair with mesh repair for incisional hernia","volume":"343","author":"Luijendijk\n              RW,","year":"2000","unstructured":"Luijendijk\n              RW, \n            \n              Hop\n              WC, \n            \n              van den Tol\n              MP, \n            \n              de Lange\n              DC, \n            \n              Braaksma\n              MM, \n            \n              IJzermans\n              JN\n            \n            et al\n          . A comparison of suture repair with mesh repair for incisional hernia. N Engl J Med2000;343(6):392\u2013398"},{"issue":"1","key":"i0020-8868-98-4-379-b04","series-title":"Hernia","first-page":"23","article-title":"Multicentric observational cohort study evaluating a composite mesh with incorporated oxidized regenerated cellulose in laparoscopic ventral hernia repair","volume":"13","author":"Berrevoet\n              F,","year":"2009","unstructured":"Berrevoet\n              F, \n            \n              Fierens\n              K, \n            \n              De Gols\n              J, \n            \n              Navez\n              B, \n            \n              Van Bastelaere\n              W, \n            \n              Meir\n              E\n            \n            et al\n          . Multicentric observational cohort study evaluating a composite mesh with incorporated oxidized regenerated cellulose in laparoscopic ventral hernia repair. 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Am Surg2010;76(1):96\u2013100"},{"issue":"8","key":"i0020-8868-98-4-379-b13","series-title":"Ostomy Wound Manage","first-page":"52","article-title":"Utilization of bovine acellular dermal matrix for abdominal wall reconstruction: a retrospective case series","volume":"55","author":"Wietfeldt\n              ED,","year":"2009","unstructured":"Wietfeldt\n              ED, \n            \n              Hassan\n              I, \n            \n              Rakinic\n              J. \n          \n          Utilization of bovine acellular dermal matrix for abdominal wall reconstruction: a retrospective case series. 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Inflamm Bowel Dis2009;15(8):1208\u20131212"},{"issue":"15","key":"i0020-8868-98-4-379-b18","series-title":"World J Gastroenterol","first-page":"1928","article-title":"Use of biological meshes for abdominal wall reconstruction in highly contaminated fields","volume":"16","author":"Cavallaro\n              A,","year":"2010","unstructured":"Cavallaro\n              A, \n            \n              Lo Menzo\n              E, \n            \n              Di Vita\n              M, \n            \n              Zanghi\n              A, \n            \n              Cavallaro\n              V, \n            \n              Veroux\n              PF\n            \n            et al\n          . Use of biological meshes for abdominal wall reconstruction in highly contaminated fields. 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Curr Surg2006;63(4):255\u2013258"},{"issue":"2","key":"i0020-8868-98-4-379-b20","series-title":"Am Surg","first-page":"144","article-title":"Repair of high-risk incisional hernias and traumatic abdominal wall defects with porcine mesh","volume":"77","author":"Byrnes\n              MC,","year":"2011","unstructured":"Byrnes\n              MC, \n            \n              Irwin\n              E, \n            \n              Carlson\n              D, \n            \n              Campeau\n              A, \n            \n              Gipson\n              JC, \n            \n              Beal\n              A\n            \n            et al\n          . Repair of high-risk incisional hernias and traumatic abdominal wall defects with porcine mesh. 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Hernia2011;15(2):157\u2013164"},{"issue":"3","key":"i0020-8868-98-4-379-b30","series-title":"J Am Coll Surg","first-page":"368","article-title":"Comparison of cross-linked and non-cross-linked porcine acellular dermal matrices for ventral hernia repair","volume":"211","author":"Butler\n              CE,","year":"2010","unstructured":"Butler\n              CE, \n            \n              Burns\n              NK, \n            \n              Campbell\n              KT, \n            \n              Mathur\n              AB, \n            \n              Jaffari\n              MV, \n            \n              Rios\n              CN. \n          \n          Comparison of cross-linked and non-cross-linked porcine acellular dermal matrices for ventral hernia repair. J Am Coll Surg2010;211(3):368\u2013376"},{"issue":"3","key":"i0020-8868-98-4-379-b31","series-title":"Ann Plast Surg","first-page":"264","article-title":"Utilization of human cadaveric acellular dermis for abdominal hernia reconstruction","volume":"58","author":"Espinosa-de-los-Monteros\n              A,","year":"2007","unstructured":"Espinosa-de-los-Monteros\n              A, \n            \n              de la Torre\n              JI, \n            \n              Marrero\n              I, \n            \n              Andrades\n              P, \n            \n              Davis\n              MR, \n            \n              Vasconez\n              LO. \n          \n          Utilization of human cadaveric acellular dermis for abdominal hernia reconstruction. 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Am J Surg2009;197(5):599\u2013603"},{"issue":"1","key":"i0020-8868-98-4-379-b33","series-title":"Am J Surg","first-page":"80","article-title":"Greater risk of incisional hernia with morbidly obese than steroid-dependent patients and low recurrence with prefascial polypropylene mesh","volume":"171","author":"Sugerman\n              HJ,","year":"1996","unstructured":"Sugerman\n              HJ, \n            \n              Kellum\n              JM\n              Jr, \n            \n              Reines\n              HD, \n            \n              DeMaria\n              EJ, \n            \n              Newsome\n              HH, \n            \n              Lowry\n              JW. \n          \n          Greater risk of incisional hernia with morbidly obese than steroid-dependent patients and low recurrence with prefascial polypropylene mesh. Am J Surg1996;171(1):80\u201384"},{"issue":"3","key":"i0020-8868-98-4-379-b34","series-title":"Cir Esp","first-page":"158","article-title":"Prosthetic infection after hernioplasty. Five years experience","volume":"85","author":"Bueno Lled\u00f3\n              J,","year":"2009","unstructured":"Bueno Lled\u00f3\n              J, \n            \n              Sosa Quesada\n              Y, \n            \n              G\u00f3mez i Gavara\n              I, \n            \n              Vaqu\u00e9 Urbaneja\n              J, \n            \n              Carbonell Tatay\n              F, \n            \n              Bonaf\u00e9 Diana\n              S\n            \n            et al\n          . Prosthetic infection after hernioplasty. Five years experience. Cir Esp2009;85(3):158\u2013164"},{"issue":"4","key":"i0020-8868-98-4-379-b35","series-title":"Surgery","first-page":"703","article-title":"Use of human acellular dermal matrix for hernia repair: friend or foe?","volume":"144","author":"Candage\n              R,","year":"2008","unstructured":"Candage\n              R, \n            \n              Jones\n              K, \n            \n              Luchette\n              FA, \n            \n              Sinacore\n              JM, \n            \n              Vandevender\n              D, \n            \n              Reed\n              RL. \n          \n          Use of human acellular dermal matrix for hernia repair: friend or foe?\n          Surgery\n          2008;144(4):703\u2013709"}],"container-title":["International Surgery"],"original-title":[],"link":[{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/98\/4\/article-p379.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/international-surgery\/article-pdf\/98\/4\/379\/2347468\/intsurg-d-13-00053_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/98\/4\/article-p379.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/98\/4\/article-p379.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T18:59:50Z","timestamp":1751482790000},"score":1,"resource":{"primary":{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/98\/4\/article-p379.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":35,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.9738\/intsurg-d-13-00053.1","relation":{},"ISSN":["0020-8868","2520-2456"],"issn-type":[{"value":"0020-8868","type":"print"},{"value":"2520-2456","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}