{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T06:01:52Z","timestamp":1787032912071,"version":"build-2736575974"},"reference-count":17,"publisher":"International College of Surgeons","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We aimed to compare the clinical outcome and cost of early versus delayed laparoscopic cholecystectomy for acute cholecystitis. Sixty patients with acute cholecystitis were randomized into early (within 24 hours of admission) or delayed (after 6\u20138 weeks of conservative treatment) laparoscopic cholecystectomy groups. There was no significant difference between study groups in terms of operation time and rates for conversion to open cholecystectomy. On the other hand, total hospital stay was longer (5.2 \u00b1 1.40 versus 7.8 \u00b1 1.65 days;\n                    <jats:italic>P<\/jats:italic>\n                    = 0.04) and total costs were higher (2500.97 \u00b1 755.265 versus 3713.47 \u00b1 517.331 Turkish Lira;\n                    <jats:italic>P<\/jats:italic>\n                    = 0.03) in the delayed laparoscopic cholecystectomy group. Intraoperative and postoperative complications were recorded in 8 patients in the early laparoscopic cholecystectomy group, whereas no complications occurred in the delayed laparoscopic cholecystectomy group (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.002). Despite intraoperative and postoperative complications being associated more with early laparoscopic cholecystectomy compared with delayed intervention, early laparoscopic cholecystectomy should be preferred for treatment of acute cholecystitis because of its advantages of shorter hospital stay and lower cost.\n                  <\/jats:p>","DOI":"10.9738\/intsurg-d-13-00068.1","type":"journal-article","created":{"date-parts":[[2014,1,20]],"date-time":"2014-01-20T17:47:19Z","timestamp":1390240039000},"page":"56-61","source":"Crossref","is-referenced-by-count":70,"title":["Early Versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis: A Prospective, Randomized Study"],"prefix":"10.9738","volume":"99","author":[{"given":"Alper Bilal","family":"\u00d6zkarde\u015f","sequence":"first","affiliation":[{"name":"Department of General Surgery, Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Toka\u00e7","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ersin G\u00fcrkan","family":"Dumlu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birkan","family":"Bozkurt","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet Burak","family":"\u00c7ift\u00e7i","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahri","family":"Yeti\u015fir","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Y\u0131ld\u0131r\u0131m Beyaz\u0131t University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4721","reference":[{"issue":"9","key":"i0020-8868-99-1-56-b01","series-title":"Surg Endosc","first-page":"1323","article-title":"Early versus delayed laparoscopic cholecystectomy for acute cholecystitis: a prospective randomized trial","volume":"18","author":"Kolla\n              SB,","year":"2004","unstructured":"Kolla\n              SB, \n            \n              Aggarwal\n              S, \n            \n              Kumar\n              A, \n            \n              Kumar\n              R, \n            \n              Chumber\n              S, \n            \n              Parshad\n              R\n            \n            et al\n          . 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Hepatogastroenterology2009;56(89):26\u201328"},{"issue":"2","key":"i0020-8868-99-1-56-b05","series-title":"Br J Surg","first-page":"141","article-title":"Meta-analysis of randomized controlled trials on the safety and effectiveness of early versus delayed laparoscopic cholecystectomy for acute cholecystitis","volume":"97","author":"Gurusamy\n              K,","year":"2010","unstructured":"Gurusamy\n              K, \n            \n              Samraj\n              K, \n            \n              Gluud\n              C, \n            \n              Wilson\n              E, \n            \n              Davidson\n              BR. \n          \n          Meta-analysis of randomized controlled trials on the safety and effectiveness of early versus delayed laparoscopic cholecystectomy for acute cholecystitis. 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Arch Surg2012;147(11):1031\u20131035"},{"issue":"2","key":"i0020-8868-99-1-56-b09","series-title":"Int J Evid Based Health","first-page":"112","article-title":"Early laparoscopic cholecystectomy in a district general hospital: is it safe and feasible?","volume":"10","author":"Panagiotopoulou\n              IG,","year":"2012","unstructured":"Panagiotopoulou\n              IG, \n            \n              Carter\n              N, \n            \n              Lewis\n              MC, \n            \n              Rao\n              S. \n          \n          Early laparoscopic cholecystectomy in a district general hospital: is it safe and feasible?\n          Int J Evid Based Health\n          2012;10(2):112\u2013116"},{"issue":"5","key":"i0020-8868-99-1-56-b10","series-title":"Rev Col Bras Cir","first-page":"436","article-title":"Uncomplicated acute cholecystitis: early or delayed laparoscopic cholecystectomy?","volume":"39","author":"Sankarankutty\n              A,","year":"2012","unstructured":"Sankarankutty\n              A, \n            \n              da Luz\n              LT, \n            \n              De Campos\n              T, \n            \n              Rizoli\n              S, \n            \n              Fraga\n              GP, \n            \n              Nascimento\n              B\n              Jr. \n          \n          Uncomplicated acute cholecystitis: early or delayed laparoscopic cholecystectomy?\n          Rev Col Bras Cir\n          2012;39(5):436\u2013440"},{"issue":"1","key":"i0020-8868-99-1-56-b11","series-title":"JSLS","first-page":"65","article-title":"Operative timing of laparoscopic cholecystectomy for acute cholecystitis in a Japanese institute","volume":"16","author":"Ohta\n              M,","year":"2012","unstructured":"Ohta\n              M, \n            \n              Iwashita\n              Y, \n            \n              Yada\n              K, \n            \n              Ogawa\n              T, \n            \n              Kai\n              S, \n            \n              Ishio\n              T\n            \n            et al\n          . Operative timing of laparoscopic cholecystectomy for acute cholecystitis in a Japanese institute. JSLS2012;16(1):65\u201370"},{"key":"i0020-8868-99-1-56-b12","series-title":"Cochrane Database Syst Rev","article-title":"Early versus delayed laparoscopic cholecystectomy for biliary colic","author":"Gurusamy\n              KS,","year":"2008","unstructured":"Gurusamy\n              KS, \n            \n              Samraj\n              K, \n            \n              Fusai\n              G, \n            \n              Davidson\n              BR. \n          \n          Early versus delayed laparoscopic cholecystectomy for biliary colic. 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Br J Surg2010;97(2):210\u2013219"},{"issue":"1","key":"i0020-8868-99-1-56-b17","series-title":"Surg Endosc","first-page":"256","article-title":"Cost-utility of early versus delayed laparoscopic cholecystectomy for acute cholecystitis","volume":"27","author":"Johner\n              A,","year":"2013","unstructured":"Johner\n              A, \n            \n              Raymakers\n              A, \n            \n              Wiseman\n              SM. \n          \n          Cost-utility of early versus delayed laparoscopic cholecystectomy for acute cholecystitis. Surg Endosc2013;27(1):256\u2013262"}],"container-title":["International Surgery"],"original-title":[],"link":[{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/99\/1\/article-p56.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/international-surgery\/article-pdf\/99\/1\/56\/2213767\/intsurg-d-13-00068_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/99\/1\/article-p56.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/99\/1\/article-p56.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T15:08:56Z","timestamp":1751468936000},"score":1,"resource":{"primary":{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/99\/1\/article-p56.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":17,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.9738\/intsurg-d-13-00068.1","relation":{},"ISSN":["0020-8868","2520-2456"],"issn-type":[{"value":"0020-8868","type":"print"},{"value":"2520-2456","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}