{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T17:23:30Z","timestamp":1785605010311,"version":"3.56.0"},"reference-count":13,"publisher":"International College of Surgeons","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:p>We report a rare case of disseminated carcinomatosis of the bone marrow from rectal cancer with disseminated intravascular coagulation (DIC). A 65-year-old man was admitted with melena and low back pain at rest. X-ray examination showed rectal cancer with multiple bone metastases. Laboratory examination showed severe anemia and DIC. Histologic examination showed disseminated carcinomatosis of the bone marrow. The DIC was considered to be caused by disseminated carcinomatosis of the bone marrow from rectal cancer, and we immediately started treatment with anti-DIC therapy and anticancer chemotherapy with the modified FOLFOX6 regimen (mFOLFOX6). After some response to therapy, the patient's general condition deteriorated, and he died 128 days after admission. This is the first English report showing disseminated carcinomatosis of the bone marrow from colorectal cancer treated with mFOLFOX6.<\/jats:p>","DOI":"10.9738\/intsurg-d-13-00130.1","type":"journal-article","created":{"date-parts":[[2014,12,8]],"date-time":"2014-12-08T16:00:08Z","timestamp":1418054408000},"page":"518-522","source":"Crossref","is-referenced-by-count":12,"title":["Rectal Cancer With Disseminated Carcinomatosis of the Bone Marrow: Report of a Case"],"prefix":"10.9738","volume":"99","author":[{"given":"Yuichiro","family":"Nakashima","sequence":"first","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Takeishi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Guntani","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Tsujita","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiji","family":"Yoshinaga","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayumi","family":"Matsuyama","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoharu","family":"Hamatake","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Tsutsui","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumu","family":"Fujihara","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruyoshi","family":"Ishida","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4721","reference":[{"issue":"9","key":"i0020-8868-99-5-518-b01","series-title":"J Gastroenterol Hepatol","first-page":"1537","article-title":"Clinicopathological features and clinical outcomes of gastric cancer that initially presents with disseminated intravascular coagulation: a retrospective study","volume":"25","author":"Rhee\n              J,","year":"2010","unstructured":"Rhee\n              J, \n            \n              Han\n              SW, \n            \n              Oh\n              DY, \n            \n              Im\n              SA, \n            \n              Kim\n              TY, \n            \n              Bang\n              YJ\n            \n          . 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