{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T01:29:54Z","timestamp":1768440594644,"version":"3.49.0"},"reference-count":15,"publisher":"International College of Surgeons","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:p>We report a case of malignant melanoma of unknown primary origin presenting metastasis in various organs as well as intraluminal gallbladder bleeding due to gallbladder metastasis. A 58-year-old woman was diagnosed with stage IV metastatic malignant melanoma. Because she exhibited acute cholecystitis and hemobilia due to malignant melanoma of the gallbladder, laparoscopic cholecystectomy was performed to relieve the symptoms. The resected gallbladder specimen showed a pedunculated black mass indicating malignant melanoma. Pathologic examination and immunohistochemical analysis revealed malignant melanoma of the gallbladder. Only a few cases of gallbladder malignant melanoma presenting hemobilia have been reported; here we present our case, including the experience of multidisciplinary treatment.<\/jats:p>","DOI":"10.9738\/intsurg-d-13-00143.1","type":"journal-article","created":{"date-parts":[[2014,12,8]],"date-time":"2014-12-08T16:00:08Z","timestamp":1418054408000},"page":"600-605","source":"Crossref","is-referenced-by-count":15,"title":["Multiple Metastatic Malignant Melanoma Presenting Intraluminal Gallbladder Bleeding"],"prefix":"10.9738","volume":"99","author":[{"given":"Hisashi","family":"Onozawa","sequence":"first","affiliation":[{"name":"Department of Surgery and 2Department of Pathology, Hoshi General Hospital, Koriyama, Japan"},{"name":"Department of Organ Regulatory Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motonobu","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Surgery and 2Department of Pathology, Hoshi General Hospital, Koriyama, Japan"},{"name":"Department of Organ Regulatory Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayaka","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Surgery and 2Department of Pathology, Hoshi General Hospital, Koriyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Sakuma","sequence":"additional","affiliation":[{"name":"Department of Surgery and 2Department of Pathology, Hoshi General Hospital, Koriyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masami","family":"Matsuzaki","sequence":"additional","affiliation":[{"name":"Department of Surgery and 2Department of Pathology, Hoshi General Hospital, Koriyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoto","family":"Katagata","sequence":"additional","affiliation":[{"name":"Department of Surgery and 2Department of Pathology, Hoshi General Hospital, Koriyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumiaki","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Surgery and 2Department of Pathology, Hoshi General Hospital, Koriyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiko","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Surgery and 2Department of Pathology, Hoshi General Hospital, Koriyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiichi","family":"Takenoshita","sequence":"additional","affiliation":[{"name":"Department of Organ Regulatory Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Nomizu","sequence":"additional","affiliation":[{"name":"Department of Surgery and 2Department of Pathology, Hoshi General Hospital, Koriyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4721","reference":[{"issue":"1","key":"i0020-8868-99-5-600-b01","series-title":"Cancer","first-page":"32","article-title":"Melanoma of the gallbladder: a review of cases seen at Duke University Medical Center","volume":"85","author":"Dong\n              XD,","year":"1999","unstructured":"Dong\n              XD, \n            \n              DeMatos\n              P, \n            \n              Prieto\n              VG, \n            \n              Seigler\n              HF. \n          \n          Melanoma of the gallbladder: a review of cases seen at Duke University Medical Center. 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