{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T16:11:00Z","timestamp":1764259860886,"version":"3.41.0"},"reference-count":16,"publisher":"International College of Surgeons","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:p>The long-term outcomes of laparoscopic splenectomy (LS) versus open splenectomy (OS) in patients with idiopathic thrombocytopenic purpura (ITP) are not known. A retrospective analysis of 73 patients who underwent splenectomy (32 LS and 41 OS) for refractory ITP between April 2003 and June 2012 was conducted. LS was associated with shorter hospital stay (<jats:italic>P<\/jats:italic> = 0.01), less blood loss and blood transfusion during surgery, quicker resumption of oral diet (<jats:italic>P<\/jats:italic> &lt; 0.0001), and earlier drain removal (<jats:italic>P<\/jats:italic> &lt; 0.01). Conversion to OS was required in 4 patients (12.5%). Operation time was significantly longer in LS (<jats:italic>P<\/jats:italic> &lt; 0.0001). Deep venous thrombosis (DVT) was observed in 1 patient after LS and in 4 patients after OS (<jats:italic>P<\/jats:italic> = 0.52). One patient died from intraperitoneal bleeding after OS, another patient developed pulmonary embolism. Median follow-up of 36 months was performed in LS group (29 of 32, 91%) and of 46 months in OS group (35 of 41, 85%), 25 patients (86%) in LS group and 32 (91%) in OS group reached sustained complete response (<jats:italic>P<\/jats:italic> = 0.792). Kaplan-Meier analysis showed that there was no significant difference in the relapse-free survival rate between the groups (<jats:italic>P<\/jats:italic> = 0.777). In conclusion, the long-term outcome of laparoscopic splenectomy is not different from that of open splenectomy for patients with ITP.<\/jats:p>","DOI":"10.9738\/intsurg-d-13-00175.1","type":"journal-article","created":{"date-parts":[[2014,5,15]],"date-time":"2014-05-15T18:05:42Z","timestamp":1400177142000},"page":"286-290","source":"Crossref","is-referenced-by-count":25,"title":["Long-Term Outcomes of Laparoscopic Splenectomy Versus Open Splenectomy for Idiopathic Thrombocytopenic Purpura"],"prefix":"10.9738","volume":"99","author":[{"given":"Yikun","family":"Qu","sequence":"first","affiliation":[{"name":"General Surgery, First Affiliated Hospital of Jiamusi University, Jiamusi, Helongjiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Xu","sequence":"additional","affiliation":[{"name":"General Surgery, First Affiliated Hospital of Jiamusi University, Jiamusi, Helongjiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengbin","family":"Jiao","sequence":"additional","affiliation":[{"name":"General Surgery, First Affiliated Hospital of Jiamusi University, Jiamusi, Helongjiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuoxin","family":"Cheng","sequence":"additional","affiliation":[{"name":"General Surgery, First Affiliated Hospital of Jiamusi University, Jiamusi, Helongjiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiyan","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Surgery, China-Japan Friendship Hospital, Beijing, China"},{"name":"General Surgery, General PLA Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4721","reference":[{"issue":"3","key":"i0020-8868-99-3-286-b01","series-title":"J Laparoendosc Adv Surg Tech A","first-page":"192","article-title":"Long-term results after splenectomy in adult idiopathic thrombocytopenic purpura: comparison between open and laparoscopic procedures","volume":"23","author":"Vecchio\n              R,","year":"2013","unstructured":"Vecchio\n              R, \n            \n              Marchese\n              S, \n            \n              Intagliata\n              E, \n            \n              Swehli\n              E, \n            \n              Ferla\n              F, \n            \n              Cacciola\n              E. \n          \n          Long-term results after splenectomy in adult idiopathic thrombocytopenic purpura: comparison between open and laparoscopic procedures. J Laparoendosc Adv Surg Tech A2013;23(3):192\u2013198"},{"issue":"1","key":"i0020-8868-99-3-286-b02","series-title":"Int Surg","first-page":"55","article-title":"Management of postoperative complications following splenectomy","volume":"98","author":"Qu\n              Y,","year":"2013","unstructured":"Qu\n              Y, \n            \n              Ren\n              S, \n            \n              Li\n              C, \n            \n              Qian\n              S, \n            \n              Liu\n              P. \n          \n          Management of postoperative complications following splenectomy. Int Surg2013;98(1):55\u201360"},{"issue":"6","key":"i0020-8868-99-3-286-b03","series-title":"Pediatr Blood Cancer","first-page":"829","article-title":"Splenectomy in children with idiopathic thrombocytopenic purpura: a prospective study of 134 children from the Intercontinental Childhood ITP Study Group","volume":"49","author":"K\u00fchne\n              T,","year":"2007","unstructured":"K\u00fchne\n              T, \n            \n              Blanchette\n              V, \n            \n              Buchanan\n              GR, \n            \n              Ramenghi\n              U, \n            \n              Donato\n              H, \n            \n              Tamminga\n              RY\n            \n            et al\n          . Splenectomy in children with idiopathic thrombocytopenic purpura: a prospective study of 134 children from the Intercontinental Childhood ITP Study Group. 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Am J Surg1996;172(5):596\u2013599; discussion 599\u2013601"},{"issue":"1","key":"i0020-8868-99-3-286-b09","series-title":"J Am Coll Surg","first-page":"49","article-title":"Laparoscopic or open splenectomy for hematologic disease: which approach is superior?","volume":"185","author":"Friedman\n              RL,","year":"1997","unstructured":"Friedman\n              RL, \n            \n              Hiatt\n              JR, \n            \n              Korman\n              JL, \n            \n              Facklis\n              K, \n            \n              Cymerman\n              J, \n            \n              Phillips\n              EH. \n          \n          Laparoscopic or open splenectomy for hematologic disease: which approach is superior?\n          J Am Coll Surg\n          1997;185(1):49\u201354"},{"issue":"2","key":"i0020-8868-99-3-286-b10","series-title":"Surg Endosc","first-page":"108","article-title":"Laparoscopic splenectomy: the emerging standard","volume":"11","author":"Glasgow\n              RE,","year":"1997","unstructured":"Glasgow\n              RE, \n            \n              Yee\n              LF, \n            \n              Mulvihill\n              SJ. \n          \n          Laparoscopic splenectomy: the emerging standard. 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World J Surg2006;30(4): 553\u2013559"}],"container-title":["International Surgery"],"original-title":[],"link":[{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/99\/3\/article-p286.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/international-surgery\/article-pdf\/99\/3\/286\/2216673\/intsurg-d-13-00175_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/99\/3\/article-p286.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/99\/3\/article-p286.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T19:07:54Z","timestamp":1751483274000},"score":1,"resource":{"primary":{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/99\/3\/article-p286.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":16,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.9738\/intsurg-d-13-00175.1","relation":{},"ISSN":["0020-8868","2520-2456"],"issn-type":[{"type":"print","value":"0020-8868"},{"type":"electronic","value":"2520-2456"}],"subject":[],"published":{"date-parts":[[2014]]}}}