{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T01:21:35Z","timestamp":1768440095409,"version":"3.49.0"},"reference-count":13,"publisher":"International College of Surgeons","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:p>Leiomyomas (LMs) may appear throughout the entire gastrointestinal tract but are rarely seen in the colon-rectum and only 5 of those measured greater than 15 cm in diameter. Pain and palpable abdominal mass are the most common symptoms. Surgical resection is the treatment of choice for most LMs. We here describe a case of a 46-year-old woman who presented with a 3-month history of abdominal pain associated with worsening constipation and abdominal distension. A pelvic solid, polylobulate, left-sided mass was noted on examination. Preoperative findings revealed a dishomogeneous sigmoid mass with calcified spots compressing small intestine and bladder. At laparotomy, a large polylobulate and well-circumscribed mass arising from the descending colon mesentery and displacing small intestine, uterus, and ovaries. A segmental colon resection was performed. An extraluminal 18- \u00d7 12- \u00d7 5-cm paucicellular sigmoid colon leiomyoma was histologically diagnosed. Our case is one of the few giant (&gt;15 cm) sigmoid colon LMs reported in the literature. Although rare and benign in nature, LMs of the colon can cause life-threatening complications that could require emergency treatment and they should be included in the differential diagnosis of large abdominopelvic masses. Follow-up after surgery is necessary for tumors with any atypia or mitotic activity.<\/jats:p>","DOI":"10.9738\/intsurg-d-14-00054.1","type":"journal-article","created":{"date-parts":[[2015,5,26]],"date-time":"2015-05-26T14:32:12Z","timestamp":1432650732000},"page":"805-808","source":"Crossref","is-referenced-by-count":12,"title":["Giant Extraluminal Leiomyoma of the Colon: Rare Cause of Symptomatic Pelvic Mass"],"prefix":"10.9738","volume":"100","author":[{"given":"Andrea","family":"Sagnotta","sequence":"first","affiliation":[{"name":"Department of General Surgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Sparagna","sequence":"additional","affiliation":[{"name":"Department of General Surgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Uccini","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Medicine, St. Andrea Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Via di Grottarossa, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Mercantini","sequence":"additional","affiliation":[{"name":"Department of General Surgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4721","reference":[{"issue":"4","key":"i0020-8868-100-5-805-b01","series-title":"World J Surg","first-page":"430","article-title":"Tumors of the appendix and colon","volume":"24","author":"Hatch\n              KF,","year":"2000","unstructured":"Hatch\n              KF, \n            \n              Blanchard\n              K, \n            \n              Hatch\n              G\n              III, \n            \n              Wertheimer-Hatch\n              L, \n            \n              Davis\n              GB, \n            \n              Foster\n              RS\n              Jr\n            \n            et al\n          . 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A 10-year experience","volume":"18","author":"Spiliotis\n              J,","year":"1992","unstructured":"Spiliotis\n              J, \n            \n              Scopa\n              CD, \n            \n              Kyriakopoulou\n              D, \n            \n              Pitsis\n              A, \n            \n              Melachrinou\n              M, \n            \n              Tzoracoleftherakis\n              E\n            \n            et al\n          . Smooth muscle tumors of the gastrointestinal tract. A 10-year experience. 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