{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:36:21Z","timestamp":1790285781075,"version":"4.1.0"},"reference-count":14,"publisher":"International College of Surgeons","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:p>In the present study, we aim to share our clinical experience in patients with spontaneous splenic rupture. Splenic rupture without trauma is known as spontaneous splenic rupture. The major problems in the management of spontaneous splenic rupture are missed or delayed diagnosis due to the lack of trauma in most cases. The records of all patients, who were admitted to Cerrahpa\u015fa Medical Faculty, Istanbul University, were retrospectively reviewed from January 2000 to March 2013. Twelve patients were admitted to the emergency department and they were diagnosed with spontaneous splenic rupture. The mean age was 47.6 years. All patients had complaints of abdominal pain. The mean hematocrit value was 22%. Radiologic assessment revealed hemoperitoneum and\/or subcapsular hematoma in 8 patients while splenic abscess was diagnosed in 2 patients. Eleven patients underwent splenectomy whereas one was managed conservatively. The most common cause of spontaneous splenic rupture was determined to be use of anticoagulants. Etiology was considered to be idiopathic in 1 patient. Two patients died in the postoperative period. Although rare, spontaneous splenic rupture must be suspected in emergency patients who have used especially anticoagulants and antiaggregants and who have had no recent history of trauma. One of the important causes of mortality is missed or delayed diagnosis.<\/jats:p>","DOI":"10.9738\/intsurg-d-14-00143.1","type":"journal-article","created":{"date-parts":[[2014,12,2]],"date-time":"2014-12-02T00:06:49Z","timestamp":1417478809000},"page":"714-718","source":"Crossref","is-referenced-by-count":63,"title":["Characteristics of Patients With Spontaneous Splenic Rupture"],"prefix":"10.9738","volume":"99","author":[{"given":"Pinar Cigdem","family":"Kocael","sequence":"first","affiliation":[{"name":"Department of General Surgery, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman","family":"Simsek","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail Ahmet","family":"Bilgin","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onur","family":"Tutar","sequence":"additional","affiliation":[{"name":"Department of Radiology, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaya","family":"Saribeyoglu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salih","family":"Pekmezci","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ertugrul","family":"Goksoy","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Istanbul University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4721","reference":[{"issue":"10","key":"i0020-8868-99-6-714-b01","series-title":"Br J Surg","first-page":"1114","article-title":"Systematic review of atraumatic splenic rupture","volume":"96","author":"Renzulli\n              P,","year":"2009","unstructured":"Renzulli\n              P, \n            \n              Hostettler\n              A, \n            \n              Schoepfer\n              A, \n            \n              Gloor\n              B, \n            \n              Candinas\n              D. \n          \n          Systematic review of atraumatic splenic rupture. Br J Surg2009;96(10):1114\u20131121"},{"issue":"1","key":"i0020-8868-99-6-714-b02","series-title":"J R Coll Surg Edinb","first-page":"437","article-title":"Atraumatic rupture of the spleen in adults","volume":"47","author":"Debnath\n              D,","year":"2002","unstructured":"Debnath\n              D, \n            \n              Valerio\n              D. \n          \n          Atraumatic rupture of the spleen in adults. J R Coll Surg Edinb2002;47(1):437\u2013445"},{"issue":"8","key":"i0020-8868-99-6-714-b03","series-title":"Hosp Pract","first-page":"47","article-title":"Infectious mononucleosis: recognition and management","volume":"12","author":"Lai\n              P.","year":"1977","unstructured":"Lai\n              P. \n          \n          Infectious mononucleosis: recognition and management. Hosp Pract1977;12(8):47\u201352"},{"issue":"2","key":"i0020-8868-99-6-714-b04","series-title":"Eur J Emerg Med","first-page":"124","article-title":"Atraumatic splenic rupture: a 6-year case series","volume":"18","author":"Elvy\n              A,","year":"2011","unstructured":"Elvy\n              A, \n            \n              Harbach\n              L, \n            \n              Bhangu\n              A. \n          \n          Atraumatic splenic rupture: a 6-year case series. Eur J Emerg Med2011;18(2):124\u2013126"},{"issue":"3","key":"i0020-8868-99-6-714-b05","series-title":"Forensic Sci Intl","first-page":"215","article-title":"The weight of the normal spleen","volume":"88","author":"Sprog\u00f8e-Jakobsen\n              S,","year":"1997","unstructured":"Sprog\u00f8e-Jakobsen\n              S, \n            \n              Sprog\u00f8e-Jakobsen\n              U. \n          \n          The weight of the normal spleen. Forensic Sci Intl1997;88(3):215\u2013223"},{"issue":"2","key":"i0020-8868-99-6-714-b06","series-title":"Forensic Sci Intl","first-page":"149","article-title":"Organ weight in 684 adult autopsies: new tables for a Caucasoid population","volume":"119","author":"Lorin de la Grandmaison\n              G,","year":"2001","unstructured":"Lorin de la Grandmaison\n              G, \n            \n              Clairand\n              I, \n            \n              Durigon\n              M. \n          \n          Organ weight in 684 adult autopsies: new tables for a Caucasoid population. Forensic Sci Intl2001;119(2):149\u2013154"},{"issue":"6","key":"i0020-8868-99-6-714-b07","series-title":"Am J Emerg Med","first-page":"733.e5","article-title":"Spontaneous rupture of the spleen: a rare but important differential of an acute abdomen","volume":"26","author":"Rhee\n              SJ,","year":"2008","unstructured":"Rhee\n              SJ, \n            \n              Sheena\n              Y, \n            \n              Imber\n              C. \n          \n          Spontaneous rupture of the spleen: a rare but important differential of an acute abdomen. 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