{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T04:54:55Z","timestamp":1784782495472,"version":"3.55.0"},"reference-count":22,"publisher":"International College of Surgeons","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:p>Duplication of the appendix is a rare congenital anomaly that, in adults, is most often found incidentally during surgery for other reasons. Appendicitis in the duplicated appendix is very rare and has been reported less than 10 times in the medical literature. We describe a 33-year-old woman with worsening periumbilical pain, nausea, vomiting, and fever. Physical examination showed localized peritonitis in the right lower quadrant. She had an elevated white blood cell count with neutrophilia. Computed tomography showed acute ruptured appendicitis. Diagnostic laparoscopy showed 2 appendices attached via separate bases to a single cecum with no other concurrent anomalies. Both appendices were removed laparoscopically. Histopathology confirmed normal appendiceal tissue in one and severe acute transmural appendicitis in the other. Awareness of appendiceal duplication and a thorough intraoperative inspection are critical to assess the presence of significant associated anomalies and avoid life-threatening complications.<\/jats:p>","DOI":"10.9738\/intsurg-d-14-00150.1","type":"journal-article","created":{"date-parts":[[2015,4,15]],"date-time":"2015-04-15T20:49:52Z","timestamp":1429130992000},"page":"662-665","source":"Crossref","is-referenced-by-count":12,"title":["Duplicate Appendix With Acute Ruptured Appendicitis: A Case Report"],"prefix":"10.9738","volume":"100","author":[{"given":"Sharique","family":"Nazir","sequence":"first","affiliation":[{"name":"Minimally Invasive and Bariatric Surgery, Lutheran Medical Center, Brooklyn, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Bulanov","sequence":"additional","affiliation":[{"name":"College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Iyoob Mohammed","family":"Ilyas","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Arizona, Tucson, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim I.","family":"Jabbour","sequence":"additional","affiliation":[{"name":"Department of Surgery, Brooklyn Hospital Center, Brooklyn, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry","family":"Griffith","sequence":"additional","affiliation":[{"name":"Department of Surgery, Brooklyn Hospital Center, Brooklyn, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4721","reference":[{"key":"i0020-8868-100-4-662-b01","series-title":"National Hospital Discharge Survey: Procedures by selected patient characteristics - Number by procedure category and age","year":"2010","unstructured":"Centers for Disease Control and Prevention. National Hospital Discharge Survey: Procedures by selected patient characteristics - Number by procedure category and age. Health, United States, 2010"},{"issue":"5","key":"i0020-8868-100-4-662-b02","series-title":"Am J Epidemiol","first-page":"910","article-title":"The epidemiology of appendicitis and appendectomy in the United States","volume":"132","author":"Addiss\n              DG,","year":"1990","unstructured":"Addiss\n              DG, \n            \n              Shaffer\n              N, \n            \n              Fowler\n              BS, \n            \n              Tauxe\n              RV.\n            \n          \n          The epidemiology of appendicitis and appendectomy in the United States. Am J Epidemiol1990;132(5):910\u2013925"},{"key":"i0020-8868-100-4-662-b03","series-title":"Pediatr Surg Int","first-page":"221","article-title":"Hi\u00e7s\u00f6nmez. A duplication of vermiform appendix: case report and review of the literature","volume":"7","author":"Arda\n              IS,","year":"1982","unstructured":"Arda\n              IS, \n            \n              \u015eenocak\n              ME, \n          \n          Hi\u00e7s\u00f6nmez. A duplication of vermiform appendix: case report and review of the literature. Pediatr Surg Int1982;7:221\u2013222"},{"issue":"5","key":"i0020-8868-100-4-662-b04","series-title":"Radiographics","first-page":"1063","article-title":"Gastrointestinal tract duplications: clinical, pathologic, etiologic, and radiologic considerations","volume":"13","author":"Macpherson\n              RI.","year":"1993","unstructured":"Macpherson\n              RI.\n            \n          \n          Gastrointestinal tract duplications: clinical, pathologic, etiologic, and radiologic considerations. 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Chirurg1993;64:1059\u20131061"},{"issue":"3","key":"i0020-8868-100-4-662-b10","series-title":"Surgery","first-page":"563","article-title":"Horseshoe anomaly of the appendix: a previously undescribed entity","volume":"106","author":"Mesko\n              TW,","year":"1989","unstructured":"Mesko\n              TW, \n            \n              Lugo\n              R, \n            \n              Breitholtz\n              T.\n            \n          \n          Horseshoe anomaly of the appendix: a previously undescribed entity. 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Embryology, anatomy, and surgical applications","volume":"80","author":"Schumpelick\n              V,","year":"2000","unstructured":"Schumpelick\n              V, \n            \n              Dreuw\n              B, \n            \n              Ophoff\n              K, \n            \n              Prescher\n              A.\n            \n          \n          Appendix and cecum. Embryology, anatomy, and surgical applications. Surg Clin North Am2000;80(1):295\u2013318"},{"issue":"3","key":"i0020-8868-100-4-662-b14","series-title":"J Pediatr Surg","first-page":"E5","article-title":"An exceptional combined malformation: duplication of the urinary and intestinal tracts and the vulva (04-80CR)","volume":"40","author":"Jianhong\n              L,","year":"2005","unstructured":"Jianhong\n              L, \n            \n              Xuewu\n              J, \n            \n              Xianliang\n              H.\n            \n          \n          An exceptional combined malformation: duplication of the urinary and intestinal tracts and the vulva (04-80CR). J Pediatr Surg2005;40(3):E5\u20139"},{"issue":"4","key":"i0020-8868-100-4-662-b15","series-title":"J Am Coll Surg","first-page":"426","article-title":"Duplication of the vermiform appendix in gastroschisis","volume":"189","author":"Gilchrist\n              BF,","year":"1999","unstructured":"Gilchrist\n              BF, \n            \n              Scriven\n              R, \n            \n              Nguyen\n              M, \n            \n              Nguyen\n              V, \n            \n              Klotz\n              D, \n            \n              Ramenofsky\n              ML.\n            \n          \n          Duplication of the vermiform appendix in gastroschisis. J Am Coll Surg1999;189(4):426"},{"issue":"5","key":"i0020-8868-100-4-662-b16","series-title":"Br J Urol","first-page":"577","article-title":"Rare combination of duplication of genito-urinary tract, hindgut, vertebral column and other associated anomalies","volume":"46","author":"Dutta\n              T,","year":"1974","unstructured":"Dutta\n              T, \n            \n              George\n              V, \n            \n              Meenakshi\n              PK, \n            \n              Das\n              G.\n            \n          \n          Rare combination of duplication of genito-urinary tract, hindgut, vertebral column and other associated anomalies. Br J Urol1974;46(5):577\u2013582"},{"issue":"11","key":"i0020-8868-100-4-662-b17","series-title":"Int J Surg Case Rep","first-page":"559","article-title":"Acute appendicitis in a duplicated appendix","volume":"3","author":"Christodoulidis\n              G,","year":"2012","unstructured":"Christodoulidis\n              G, \n            \n              Symeonidis\n              D, \n            \n              Spyridakis\n              M, \n            \n              Koukoulis\n              G, \n            \n              Manolakis\n              A, \n            \n              Triantafylidis\n              G\n            \n            et al\n          . Acute appendicitis in a duplicated appendix. 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Arch Surg1987;122(7):817\u2013820"},{"key":"i0020-8868-100-4-662-b20","series-title":"J Pediatr Surg","first-page":"1267","article-title":"Duplications of the alimentary tract in infants and children","volume":"30","author":"Iyer\n              CP,","year":"1995","unstructured":"Iyer\n              CP, \n            \n              Mahour\n              GH.\n            \n          \n          Duplications of the alimentary tract in infants and children. J Pediatr Surg1995;30:1267\u20131270"},{"issue":"2","key":"i0020-8868-100-4-662-b21","series-title":"Semin Diagn Pathol","first-page":"151","article-title":"Miscellaneous conditions of the appendix","volume":"21","author":"Misdraji\n              J,","year":"2004","unstructured":"Misdraji\n              J, \n            \n              Graeme-Cook\n              FM.\n            \n          \n          Miscellaneous conditions of the appendix. Semin Diagn Pathol2004;21(2):151\u2013163"},{"key":"i0020-8868-100-4-662-b22","series-title":"Med Sci Law","first-page":"124","article-title":"Duplication of the vermiform appendix: report of a case: review of the classification and medicolegal aspects","volume":"30","author":"Mitchell\n              IC,","year":"1990","unstructured":"Mitchell\n              IC, \n            \n              Nicholls\n              JC:\n            \n          \n          Duplication of the vermiform appendix: report of a case: review of the classification and medicolegal aspects. 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