{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T23:04:26Z","timestamp":1791500666830,"version":"4.3.4"},"reference-count":23,"publisher":"International College of Surgeons","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:p>A perioperative intravenous lidocaine infusion has been reported to decrease postoperative pain. The goal of this study was to evaluate the effectiveness of intravenous lidocaine in reducing postoperative pain for laparoscopic colectomy patients. Fifty-five patients scheduled for an elective laparoscopic colectomy were randomly assigned to 2 groups. Group L received an intravenous bolus injection of lidocaine 1.5 mg\/kg before intubation, followed by 2 mg\/kg\/h continuous infusion during the operation. Group C received the same dosage of saline at the same time. Postoperative pain was assessed at 2, 4, 8, 12, 24, and 48 hours after surgery by using the visual analog scale (VAS). Fentanyl consumption by patient-controlled plus investigator-controlled rescue administration and the total number of button pushes were measured at 2, 4, 8, 12, 24, and 48 hours after surgery. In addition, C-reactive protein (CRP) levels were checked on the operation day and postoperative days 1, 2, 3, and 5. VAS scores were significantly lower in group L than group C until 24 hours after surgery. Fentanyl consumption was lower in group L than group C until 12 hours after surgery. Moreover, additional fentanyl injections and the total number of button pushes appeared to be lower in group L than group C (<jats:italic>P<\/jats:italic> &lt; 0.05). The CRP level tended to be lower in group L than group C, especially on postoperative day1 and 2 and appeared to be statistically significant. The satisfaction score was higher in group L than group C (<jats:italic>P<\/jats:italic> = 0.024). Intravenous lidocaine infusion during an operation reduces pain after a laparoscopic colectomy.<\/jats:p>","DOI":"10.9738\/intsurg-d-14-00225.1","type":"journal-article","created":{"date-parts":[[2015,3,18]],"date-time":"2015-03-18T22:39:23Z","timestamp":1426718363000},"page":"394-401","source":"Crossref","is-referenced-by-count":39,"title":["Intravenous Lidocaine for Effective Pain Relief After a Laparoscopic Colectomy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study"],"prefix":"10.9738","volume":"100","author":[{"given":"EunJin","family":"Ahn","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geun Joo","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Hee","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So Young","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beom Gyu","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery, College of Medicine, Chung-Ang University College of Medicine, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Won","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4721","reference":[{"issue":"1","key":"i0020-8868-100-3-394-b01","series-title":"Colorectal Dis","first-page":"86","article-title":"Laparoscopic colorectal surgery in Great Britain and Ireland \u2013 where are we now?","volume":"7","author":"Harinath\n              G,","year":"2005","unstructured":"Harinath\n              G, \n            \n              Shah\n              PR, \n            \n              Haray\n              PN, \n            \n              Foster\n              ME. \n          \n          Laparoscopic colorectal surgery in Great Britain and Ireland \u2013 where are we now?\n          Colorectal Dis\n          2005;7(1):86\u201389"},{"issue":"10","key":"i0020-8868-100-3-394-b02","series-title":"Surg Endosc","first-page":"3555","article-title":"Impact of operative duration on postoperative pulmonary complications in laparoscopic versus open colectomy","volume":"27","author":"Owen\n              RM,","year":"2013","unstructured":"Owen\n              RM, \n            \n              Perez\n              SD, \n            \n              Lytle\n              N, \n            \n              Patel\n              A, \n            \n              Davis\n              SS, \n            \n              Lin\n              E\n            \n            et al\n          . 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