{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:33:14Z","timestamp":1761895994565,"version":"3.41.0"},"reference-count":27,"publisher":"International College of Surgeons","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:p>Schneiderian-type papilloma of the middle ear is a rare finding. We present a 46-year-old Aboriginal man with a large tympanic membrane perforation and a Schneiderian-type papilloma filling the middle ear. The aim of this study is to familiarize clinicians with this uncommon disease through discussion of its clinical presentation, diagnostic considerations and management. A search of English-language peer-reviewed literature was undertaken using the key words \u201cSchneiderian-type papilloma,\u201d \u201cinverted papilloma,\u201d and \u201cmiddle ear.\u201d A total of 29 cases (including the present case) of Schneiderian-type papilloma involving the middle ear were reviewed. Common presenting symptoms include hearing loss, otalgia, and otorrhea. Middle ear disease is associated with higher rates of recurrence and malignant transformation than its sinonasal counterpart. Radical surgical resection is the only curative treatment. Schneiderian-type papilloma is a benign, but locally aggressive, epithelial neoplasm most commonly arising in the sinonasal tract. Whilst involvement of the middle ear is extremely rare, knowledge of this condition is important due to its propensity to recur and the high rate of malignant transformation.<\/jats:p>","DOI":"10.9738\/intsurg-d-14-00242.1","type":"journal-article","created":{"date-parts":[[2015,1,7]],"date-time":"2015-01-07T11:18:05Z","timestamp":1420629485000},"page":"989-993","source":"Crossref","is-referenced-by-count":16,"title":["Schneiderian-Type Papilloma of the Middle Ear: A Review of the Literature"],"prefix":"10.9738","volume":"100","author":[{"given":"Nathan","family":"Schaefer","sequence":"first","affiliation":[{"name":"Gold Coast University Hospital, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Chong","sequence":"additional","affiliation":[{"name":"Princess Margaret Hospital for Children, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron","family":"Griffin","sequence":"additional","affiliation":[{"name":"Cairns Hospital, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Little","sequence":"additional","affiliation":[{"name":"Gold Coast University Hospital, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Gochee","sequence":"additional","affiliation":[{"name":"Cairns Hospital, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Dixon","sequence":"additional","affiliation":[{"name":"Cairns Hospital, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4721","reference":[{"issue":"4","key":"i0020-8868-100-6-989-b01","series-title":"Otolaryngol Head Neck Surg","first-page":"416","article-title":"Inverted papilloma of the middle ear and mastoid","volume":"97","author":"Stone\n              DM,","year":"1987","unstructured":"Stone\n              DM, \n            \n              Berktold\n              RE, \n            \n              Ranganathan\n              C, \n            \n              Wiet\n              RJ.\n            \n          \n          Inverted papilloma of the middle ear and mastoid. Otolaryngol Head Neck Surg1987;97(4):416\u2013418"},{"issue":"3","key":"i0020-8868-100-6-989-b02","series-title":"Rev Laryngol Otol Rhinol (Bord)","first-page":"299","article-title":"Inverted papilloma. Apropos of a multicentric case [in French, English abstract]","volume":"110","author":"Altug\n              T,","year":"1989","unstructured":"Altug\n              T, \n            \n              Sunar\n              O, \n            \n              Bilgin\n              H.\n            \n          \n          Inverted papilloma. Apropos of a multicentric case [in French, English abstract]. Rev Laryngol Otol Rhinol (Bord)1989;110(3):299\u2013301"},{"issue":"7","key":"i0020-8868-100-6-989-b03","series-title":"J Laryngol Otol","first-page":"628","article-title":"Transitional papilloma of the middle ear","volume":"106","author":"Kaddour\n              HS,","year":"1992","unstructured":"Kaddour\n              HS, \n            \n              Woodhead\n              CJ.\n            \n          \n          Transitional papilloma of the middle ear. J Laryngol Otol1992;106(7):628\u2013629"},{"issue":"11","key":"i0020-8868-100-6-989-b04","series-title":"Ann Otol Rhinol Laryngol","first-page":"890","article-title":"Inverted papilloma of the middle ear","volume":"102","author":"Roberts\n              WH,","year":"1993","unstructured":"Roberts\n              WH, \n            \n              Dinges\n              DL, \n            \n              Hanly\n              MG.\n            \n          \n          Inverted papilloma of the middle ear. Ann Otol Rhinol Laryngol1993;102(11):890\u2013892"},{"issue":"2","key":"i0020-8868-100-6-989-b05","series-title":"Am J Otol","first-page":"146","article-title":"Adenomatous lesions of the temporal bone immunohistochemical analysis and theories of histogenesis","volume":"16","author":"Bold\n              EL,","year":"1995","unstructured":"Bold\n              EL, \n            \n              Wanamaker\n              JR, \n            \n              Hughes\n              BG, \n            \n              Rhee\n              CK, \n            \n              Sebek\n              BA, \n            \n              Kinney\n              SE.\n            \n          \n          Adenomatous lesions of the temporal bone immunohistochemical analysis and theories of histogenesis. Am J Otol1995;16(2):146\u2013152"},{"issue":"9","key":"i0020-8868-100-6-989-b06","series-title":"Arch Otolaryngol Head Neck Surg","first-page":"1045","article-title":"Nasal inverted papilloma with involvement of middle ear and mastoid","volume":"121","author":"Seshul\n              MJ,","year":"1995","unstructured":"Seshul\n              MJ, \n            \n              Eby\n              TL, \n            \n              Crowe\n              DR, \n            \n              Peters\n              GE.\n            \n          \n          Nasal inverted papilloma with involvement of middle ear and mastoid. Arch Otolaryngol Head Neck Surg1995;121(9):1045\u20131048"},{"issue":"3","key":"i0020-8868-100-6-989-b07","series-title":"Ann Otol Rhinol Laryngol","first-page":"226","article-title":"Schneiderian-type mucosal papillomas of the middle ear and mastoid","volume":"105","author":"Wenig\n              BM.","year":"1996","unstructured":"Wenig\n              BM.\n            \n          \n          Schneiderian-type mucosal papillomas of the middle ear and mastoid. Ann Otol Rhinol Laryngol1996;105(3): 226\u2013233"},{"issue":"1","key":"i0020-8868-100-6-989-b08","series-title":"Head Neck","first-page":"83","article-title":"Clinical and molecular pathology of aggressive Schneiderian papilloma involving the temporal bone","volume":"20","author":"Jones\n              ME,","year":"1998","unstructured":"Jones\n              ME, \n            \n              Wackym\n              PA, \n            \n              Said-Al-Naief\n              N, \n            \n              Brandwein\n              M, \n            \n              Shaari\n              CM, \n            \n              Som\n              PM.\n            \n          \n          Clinical and molecular pathology of aggressive Schneiderian papilloma involving the temporal bone. Head Neck1998;20(1):83\u201388"},{"issue":"8","key":"i0020-8868-100-6-989-b09","series-title":"Head Neck","first-page":"703","article-title":"Intracranial extension of inverted papilloma: an unusual and potentially fatal complication","volume":"21","author":"Vural\n              E,","year":"1999","unstructured":"Vural\n              E, \n            \n              Suen\n              JY, \n            \n              Hanna\n              E.\n            \n          \n          Intracranial extension of inverted papilloma: an unusual and potentially fatal complication. Head Neck1999;21(8):703\u2013706"},{"issue":"1","key":"i0020-8868-100-6-989-b10","series-title":"Arch Otolaryngol Head Neck Surg","first-page":"79","article-title":"Pathology forum. Quiz case 2. Schneiderian-type papilloma of the middle ear","volume":"127","author":"Chhetri\n              DK,","year":"2001","unstructured":"Chhetri\n              DK, \n            \n              Gajjar\n              NA, \n            \n              Bhuta\n              S, \n            \n              Andrews\n              JC.\n            \n          \n          Pathology forum. Quiz case 2. Schneiderian-type papilloma of the middle ear. Arch Otolaryngol Head Neck Surg2001;127(1):79\u201382"},{"issue":"1","key":"i0020-8868-100-6-989-b11","series-title":"Laryngoscope","first-page":"140","article-title":"Inverting papilloma of the temporal bone","volume":"112","author":"Pou\n              AM,","year":"2002","unstructured":"Pou\n              AM, \n            \n              Vrabec\n              JT.\n            \n          \n          Inverting papilloma of the temporal bone. Laryngoscope2002;112(1):140\u2013142"},{"issue":"4","key":"i0020-8868-100-6-989-b12","series-title":"Otol Neurotol","first-page":"555","article-title":"Primary inverted papilloma of the middle ear and mastoid","volume":"23","author":"de Filippis\n              C,","year":"2002","unstructured":"de Filippis\n              C, \n            \n              Marioni\n              G, \n            \n              Tregnaghi\n              A, \n            \n              Marino\n              F, \n            \n              Gaio\n              E, \n            \n              Staffieri\n              A.\n            \n          \n          Primary inverted papilloma of the middle ear and mastoid. Otol Neurotol2002;23(4):555\u2013559"},{"issue":"3","key":"i0020-8868-100-6-989-b13","series-title":"Acta Otolaryngol","first-page":"367","article-title":"Detection of human papillomavirus in temporal bone inverted papilloma by polymerase chain reaction","volume":"123","author":"Marioni\n              G,","year":"2003","unstructured":"Marioni\n              G, \n            \n              Altavilla\n              G, \n            \n              Busatto\n              G, \n            \n              Blandamura\n              S, \n            \n              de Filippis\n              C, \n            \n              Staffieri\n              A.\n            \n          \n          Detection of human papillomavirus in temporal bone inverted papilloma by polymerase chain reaction. Acta Otolaryngol2003;123(3):367\u2013371"},{"issue":"5","key":"i0020-8868-100-6-989-b14","series-title":"Arch Otolaryngol Head Neck Surg","first-page":"553","article-title":"Temporal bone and sinonasal inverted papilloma: the same pathological entity?","volume":"129","author":"Blandamura\n              S,","year":"2003","unstructured":"Blandamura\n              S, \n            \n              Marioni\n              G, \n            \n              de Filippis\n              C, \n            \n              Giacomelli\n              L, \n            \n              Segato\n              P, \n            \n              Staffieri\n              A.\n            \n          \n          Temporal bone and sinonasal inverted papilloma: the same pathological entity?\n          Arch Otolaryngol Head Neck Surg\n          2003;129(5): 553\u2013556"},{"issue":"3","key":"i0020-8868-100-6-989-b15","series-title":"Ann Pathol","first-page":"274","article-title":"Nasal and auricular inverted papillomas [in French, English abstract]","volume":"24","author":"Bui\n              M,","year":"2004","unstructured":"Bui\n              M, \n            \n              Cales\n              V, \n            \n              Barthelme\n              A, \n            \n              Deminiere\n              C, \n            \n              Darrouzet\n              V.\n            \n          \n          Nasal and auricular inverted papillomas [in French, English abstract]. Ann Pathol2004;24(3):274\u2013277"},{"issue":"7","key":"i0020-8868-100-6-989-b16","series-title":"Sinonasal inverted papilloma with malignant transformation in the middle ear: a multicentric origin? J Laryngol Otol","first-page":"597","article-title":"Megat Shiraz MA, Hazim MY, Amran AR, Zulkarnaen AN, Wan Muhaizan WM","volume":"120","author":"Mazlina\n              S,","year":"2006","unstructured":"Mazlina\n              S, \n          \n          Megat Shiraz MA, Hazim MY, Amran AR, Zulkarnaen AN, Wan Muhaizan WM. Sinonasal inverted papilloma with malignant transformation in the middle ear: a multicentric origin? J Laryngol Otol2006;120(7):597\u2013599"},{"issue":"2","key":"i0020-8868-100-6-989-b17","series-title":"Ir J Med Sci","first-page":"597","article-title":"Tinnitus as an unusual presentation of Schneiderian papillomatosis","volume":"180","author":"Ali\n              RB,","year":"2011","unstructured":"Ali\n              RB, \n            \n              Amin\n              M, \n            \n              Hone\n              S.\n            \n          \n          Tinnitus as an unusual presentation of Schneiderian papillomatosis. Ir J Med Sci2011;180(2):597\u2013599"},{"issue":"9","key":"i0020-8868-100-6-989-b18","series-title":"Korean J Otorhinolaryngol Head Neck Surg","first-page":"781","article-title":"A case of inverted papilloma originating from the middle ear","volume":"52","author":"Jung\n              J,","year":"2009","unstructured":"Jung\n              J, \n            \n              Kim\n              Y, \n            \n              Chung\n              M.\n            \n          \n          A case of inverted papilloma originating from the middle ear. Korean J Otorhinolaryngol Head Neck Surg2009;52(9):781\u2013783"},{"key":"i0020-8868-100-6-989-b19","series-title":"Cancer Radiother","first-page":"202","article-title":"Recurrent inverted papilloma with intracranial and temporal fossa involvement: a case report and review of the literature","volume":"14","author":"Acevedo-Henao\n              CM,","year":"2010","unstructured":"Acevedo-Henao\n              CM, \n            \n              Talagas\n              M, \n            \n              Marianowski\n              R, \n            \n              Pradier\n              O.\n            \n          \n          Recurrent inverted papilloma with intracranial and temporal fossa involvement: a case report and review of the literature. Cancer Radiother2010;14:202\u2013205"},{"issue":"1","key":"i0020-8868-100-6-989-b20","series-title":"Oto Neurotol","first-page":"e7","article-title":"Inverted papilloma of the middle ear","volume":"32","author":"Inoue\n              R,","year":"2011","unstructured":"Inoue\n              R, \n            \n              Kanazawa\n              T, \n            \n              Morita\n              M, \n            \n              Iino\n              Y, \n            \n              Yamada\n              S, \n            \n              Ishida\n              T.\n            \n          \n          Inverted papilloma of the middle ear. Oto Neurotol2011;32(1):e7\u2013e8"},{"issue":"2","key":"i0020-8868-100-6-989-b21","series-title":"J Laryngol Otol","first-page":"206","article-title":"Primary temporal inverted papilloma with premalignant change","volume":"125","author":"Zhou\n              H,","year":"2011","unstructured":"Zhou\n              H, \n            \n              Chen\n              Z, \n            \n              Li\n              H, \n            \n              Xing\n              G.\n            \n          \n          Primary temporal inverted papilloma with premalignant change. J Laryngol Otol2011;125(2):206\u2013209"},{"issue":"7","key":"i0020-8868-100-6-989-b22","series-title":"Otol Neurotol","first-page":"1124","article-title":"Inverting papilloma of the temporal bone: case report and meta-analysis of risk factors","volume":"32","author":"Shen\n              J,","year":"2011","unstructured":"Shen\n              J, \n            \n              Baid\n              F, \n            \n              Mafee\n              MF, \n            \n              Petersen\n              M, \n            \n              Nguyen\n              QT.\n            \n          \n          Inverting papilloma of the temporal bone: case report and meta-analysis of risk factors. Otol Neurotol2011;32(7):1124\u20131133"},{"issue":"2","key":"i0020-8868-100-6-989-b23","series-title":"Acta Otolaryngol","first-page":"216","article-title":"Inverted papilloma of the middle ear: a case report and review of the literature","volume":"131","author":"Kainuma\n              K,","year":"2011","unstructured":"Kainuma\n              K, \n            \n              Kitoh\n              R, \n            \n              Kenji\n              S, \n            \n              Usami\n              S.\n            \n          \n          Inverted papilloma of the middle ear: a case report and review of the literature. Acta Otolaryngol2011;131(2):216\u2013220"},{"issue":"8","key":"i0020-8868-100-6-989-b24","series-title":"Laryngoscope","first-page":"1674","article-title":"Combined transnasal\/transtemporal management of the Eustachian tube for middle ear inverted papilloma","volume":"122","author":"Mitchell\n              CA,","year":"2012","unstructured":"Mitchell\n              CA, \n            \n              Ebert\n              CS, \n            \n              Buchman\n              CA, \n            \n              Zanation\n              AM.\n            \n          \n          Combined transnasal\/transtemporal management of the Eustachian tube for middle ear inverted papilloma. Laryngoscope2012;122(8):1674\u2013678"},{"issue":"7","key":"i0020-8868-100-6-989-b25","series-title":"Laryngoscope","first-page":"1615","article-title":"Bilateral inverted papilloma of the middle ear with intracranial involvement and malignant transformation: first reported case","volume":"122","author":"Dingle\n              I,","year":"2012","unstructured":"Dingle\n              I, \n            \n              Stachiw\n              N, \n            \n              Bartlett\n              A, \n            \n              Lambert\n              P.\n            \n          \n          Bilateral inverted papilloma of the middle ear with intracranial involvement and malignant transformation: first reported case. Laryngoscope2012;122(7):1615\u20131619"},{"key":"i0020-8868-100-6-989-b26","series-title":"Cummings Otolaryngology Head & Neck Surgery. 5th ed","first-page":"719","article-title":"Benign tumors of the sinonasal tract","author":"Flint\n              PW,","year":"2010","unstructured":"Flint\n              PW, \n            \n              Haughey\n              BH, \n            \n              Lund\n              VJ, \n            \n              Niparko\n              JK, \n            \n              Richardson\n              MA, \n            \n              Robbins\n              KT\n            \n          . Benign tumors of the sinonasal tract. In: LundVJ, Ed. Cummings Otolaryngology Head & Neck Surgery. 5th ed. Philadelphia: Mosby Elsevier, 2010:719\u2013721"},{"key":"i0020-8868-100-6-989-b27","series-title":"Pathology and Genetics of Head and Neck Tumours","first-page":"28","author":"Barnes\n              L,","year":"2005","unstructured":"Barnes\n              L, \n            \n              Eveson\n              JW, \n            \n              Reichart\n              P, \n            \n              Sidransky\n              D.\n            \n          \n          Pathology and Genetics of Head and Neck Tumours. Lyon, France: IARC press, 2005:28\u201332."}],"container-title":["International Surgery"],"original-title":[],"link":[{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/100\/6\/article-p989.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/international-surgery\/article-pdf\/100\/6\/989\/2209508\/intsurg-d-14-00242_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/100\/6\/article-p989.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/100\/6\/article-p989.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T19:06:36Z","timestamp":1751483196000},"score":1,"resource":{"primary":{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/100\/6\/article-p989.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":27,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.9738\/intsurg-d-14-00242.1","relation":{},"ISSN":["0020-8868","2520-2456"],"issn-type":[{"type":"print","value":"0020-8868"},{"type":"electronic","value":"2520-2456"}],"subject":[],"published":{"date-parts":[[2015,6]]}}}