{"status":"ok","message-type":"work-list","message-version":"1.0.0","message":{"facets":{},"total-results":985,"items":[{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T15:51:03Z","timestamp":1764863463310,"version":"3.46.0"},"standards-body":{"name":"United States Pharmacopeial Convention","acronym":"USP"},"reference-count":0,"publisher":"U.S. Pharmacopeial Convention","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.31003\/uspnf_m35580_30201_01","type":"standard","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T15:47:16Z","timestamp":1764863236000},"source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate"],"prefix":"10.31003","member":"14819","deposited":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T15:47:40Z","timestamp":1764863260000},"score":20.325571,"resource":{"primary":{"URL":"https:\/\/doi.usp.org\/USPNF\/USPNF_M35580_30201_01.html"}},"issued":{"date-parts":[[null]]},"references-count":0,"URL":"https:\/\/doi.org\/10.31003\/uspnf_m35580_30201_01"},{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T11:52:09Z","timestamp":1648986729899},"standards-body":{"name":"United States Pharmacopeial Convention","acronym":"USP"},"reference-count":0,"publisher":"U.S. Pharmacopeial Convention","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.31003\/uspnf_m35580_03_01","type":"standard","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T14:18:31Z","timestamp":1629123511000},"source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate"],"prefix":"10.31003","member":"14819","deposited":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T15:42:50Z","timestamp":1629128570000},"score":20.02191,"resource":{"primary":{"URL":"https:\/\/doi.usp.org\/USPNF\/USPNF_M35580_03_01.html"}},"issued":{"date-parts":[[null]]},"references-count":0,"URL":"https:\/\/doi.org\/10.31003\/uspnf_m35580_03_01"},{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T01:29:59Z","timestamp":1649122199130},"standards-body":{"name":"United States Pharmacopeial Convention","acronym":"USP"},"reference-count":0,"publisher":"U.S. Pharmacopeial Convention","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.31003\/uspnf_m35600_02_01","type":"standard","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T14:18:31Z","timestamp":1629123511000},"source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate Tablets"],"prefix":"10.31003","member":"14819","deposited":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T15:30:48Z","timestamp":1629127848000},"score":19.606361,"resource":{"primary":{"URL":"https:\/\/doi.usp.org\/USPNF\/USPNF_M35600_02_01.html"}},"issued":{"date-parts":[[null]]},"references-count":0,"URL":"https:\/\/doi.org\/10.31003\/uspnf_m35600_02_01"},{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T11:11:46Z","timestamp":1648897906509},"standards-body":{"name":"United States Pharmacopeial Convention","acronym":"USP"},"reference-count":0,"publisher":"U.S. Pharmacopeial Convention","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.31003\/uspnf_m35590_03_01","type":"standard","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T14:18:31Z","timestamp":1629123511000},"source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate Injection"],"prefix":"10.31003","member":"14819","deposited":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T15:03:00Z","timestamp":1629126180000},"score":19.52336,"resource":{"primary":{"URL":"https:\/\/doi.usp.org\/USPNF\/USPNF_M35590_03_01.html"}},"issued":{"date-parts":[[null]]},"references-count":0,"URL":"https:\/\/doi.org\/10.31003\/uspnf_m35590_03_01"},{"indexed":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T04:15:15Z","timestamp":1750220115086,"version":"3.41.0"},"standards-body":{"name":"United States Pharmacopeial Convention","acronym":"USP"},"reference-count":0,"publisher":"U.S. Pharmacopeial Convention","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.31003\/uspnf_m13897_10101_01","type":"standard","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T18:16:13Z","timestamp":1750184173000},"source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate Compounded Oral Suspension"],"prefix":"10.31003","member":"14819","deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T18:17:29Z","timestamp":1750184249000},"score":19.004583,"resource":{"primary":{"URL":"https:\/\/doi.usp.org\/USPNF\/USPNF_M13897_10101_01.html"}},"issued":{"date-parts":[[null]]},"references-count":0,"URL":"https:\/\/doi.org\/10.31003\/uspnf_m13897_10101_01"},{"indexed":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T09:57:05Z","timestamp":1726048625938},"reference-count":1,"publisher":"Qeios","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.32388\/3hmayz","type":"reference-entry","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T15:46:48Z","timestamp":1581090408000},"source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate"],"prefix":"10.32388","author":[{"name":"National Cancer Institute","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17262","published-online":{"date-parts":[[2020,2,7]]},"reference":[{"key":"ref1","unstructured":"National Cancer Institute. Glycopyrrolate. NCI Thesaurus. Code C29078."}],"container-title":["Definitions"],"language":"en","deposited":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T15:46:48Z","timestamp":1581090408000},"score":18.311098,"resource":{"primary":{"URL":"https:\/\/www.qeios.com\/read\/definition\/47913"}},"issued":{"date-parts":[[2020,2,7]]},"references-count":1,"URL":"https:\/\/doi.org\/10.32388\/3hmayz","published":{"date-parts":[[2020,2,7]]}},{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T09:24:15Z","timestamp":1649150655739},"reference-count":0,"publisher":"Springer Science and Business Media LLC","issue":"1262","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reactions Weekly"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.2165\/00128415-200912620-00046","type":"journal-article","created":{"date-parts":[[2009,8,5]],"date-time":"2009-08-05T07:33:22Z","timestamp":1249457602000},"page":"15","source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate\/neostigmine"],"prefix":"10.1007","volume":"&NA;","author":[{"family":"&NA;","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","container-title":["Reactions Weekly"],"language":"en","deposited":{"date-parts":[[2013,2,26]],"date-time":"2013-02-26T20:53:14Z","timestamp":1361911994000},"score":18.187527,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.2165\/00128415-200912620-00046"}},"subtitle":["Generalised rash (first report for glycopyrrolate): case report"],"issued":{"date-parts":[[2009,7]]},"references-count":0,"journal-issue":{"issue":"1262"},"URL":"https:\/\/doi.org\/10.2165\/00128415-200912620-00046","ISSN":["0114-9954"],"issn-type":[{"value":"0114-9954","type":"print"}],"published":{"date-parts":[[2009,7]]}},{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T05:47:46Z","timestamp":1792388866038,"version":"4.4.0"},"reference-count":0,"publisher":"Dr. Yashwant Research Labs Pvt. Ltd.","issue":"75s","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJDDT"],"DOI":"10.25258\/ijddt.16.75s.191","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T05:22:46Z","timestamp":1792387366000},"source":"Crossref","is-referenced-by-count":0,"title":["COMPARISON OF LOW DOSE SUGAMMADEX WITH NEOSTIGMINE PLUS GLYCOPYRROLATE VERSUS NEOSTIGMINE PLUS GLYCOPYRROLATE FOR EXTUBATION"],"prefix":"10.25258","volume":"16","member":"10897","published-online":{"date-parts":[[2026,10,19]]},"container-title":["International Journal of Drug Delivery Technology"],"link":[{"URL":"https:\/\/impactfactor.org\/PDF\/IJDDT\/16\/IJDDT,Vol16,Issue75s,Article191.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T05:22:48Z","timestamp":1792387368000},"score":17.665546,"resource":{"primary":{"URL":"https:\/\/impactfactor.org\/PDF\/IJDDT\/16\/IJDDT,Vol16,Issue75s,Article191.pdf"}},"issued":{"date-parts":[[2026,10,19]]},"references-count":0,"journal-issue":{"issue":"75s","published-online":{"date-parts":[[2026,10,19]]}},"URL":"https:\/\/doi.org\/10.25258\/ijddt.16.75s.191","ISSN":["0975-4415"],"issn-type":[{"value":"0975-4415","type":"electronic"}],"published":{"date-parts":[[2026,10,19]]}},{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:30:24Z","timestamp":1791318624640,"version":"4.3.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[1998,9,1]],"date-time":"1998-09-01T00:00:00Z","timestamp":904608000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2002,1,4]],"date-time":"2002-01-04T00:00:00Z","timestamp":1010102400000},"content-version":"vor","delay-in-days":1221,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical and Experimental Dermatology"],"published-print":{"date-parts":[[1998,9]]},"DOI":"10.1046\/j.1365-2230.1998.00356.x","type":"journal-article","created":{"date-parts":[[2003,3,11]],"date-time":"2003-03-11T09:55:27Z","timestamp":1047376527000},"page":"204-205","source":"Crossref","is-referenced-by-count":36,"title":["The use of topical glycopyrrolate in the treatment of hyperhidrosis"],"prefix":"10.1093","volume":"23","author":[{"family":"SEUKERAN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"HIGHET","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2002,1,4]]},"reference":[{"key":"b1_65","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.123.7.893"},{"key":"b2_66","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0025-6196(12)62635-4","volume":"61","author":"White JW","year":"1986","journal-title":"Mayo Clin Proc"},{"key":"b3_67","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1001\/archderm.1954.01540180063009","volume":"69","author":"Shelley WB","year":"1954","journal-title":"Arch Dermatol"},{"key":"b4_68","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.97.3.327"},{"key":"b5_69","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1038\/jid.1969.171","volume":"53","author":"Gordon BI","year":"1968","journal-title":"J Invest Dermatol"},{"key":"b6_70","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1159\/000250345","volume":"161","author":"Jensen O","year":"1980","journal-title":"Dermatologica"},{"key":"b7_71","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1365-2133.1974.tb06722.x","volume":"91","author":"Abell E","year":"1974","journal-title":"Br J Dermatol"},{"key":"b8_72","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1524-4725.1985.tb01289.x","volume":"11","author":"Stenquist B","year":"1985","journal-title":"J Dermatol Surg Oncol"},{"key":"b9_73","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/0190-9622(95)90015-2","volume":"33","author":"Drott C","year":"1995","journal-title":"J Am Acad Dermatol"},{"key":"b10_74","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/S0140-6736(05)64861-1","volume":"349","author":"Naumann M","year":"1997","journal-title":"Lancet"},{"key":"b11_75","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/S0140-6736(05)62729-8","volume":"349","author":"Schnider P","year":"1997","journal-title":"Lancet"},{"key":"b12_76","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1288\/00005537-197811000-00010","volume":"88","author":"Hays LL","year":"1978","journal-title":"Laryngoscope"},{"key":"b13_77","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/0190-9622(93)70042-R","volume":"28","author":"Reinauer S","year":"1993","journal-title":"J Am Acad Dermatol"},{"key":"b14_78","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1177\/019459988209000410","volume":"90","author":"Hays LL","year":"1982","journal-title":"Otolaryngol Head Neck Surg"},{"key":"b15_79","first-page":"479","volume":"102","author":"May JS","year":"1989","journal-title":"New Zealand Med J"}],"container-title":["Clinical and Experimental Dermatology"],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1046%2Fj.1365-2230.1998.00356.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1046\/j.1365-2230.1998.00356.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T20:39:19Z","timestamp":1704314359000},"score":16.92015,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/23\/5\/204\/6627635"}},"subtitle":["GLYCOPYRROLATE FOR HYPERHIDROSIS"],"issued":{"date-parts":[[1998,9]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1998,9]]}},"URL":"https:\/\/doi.org\/10.1046\/j.1365-2230.1998.00356.x","archive":["Portico"],"ISSN":["0307-6938"],"issn-type":[{"value":"0307-6938","type":"print"}],"published":{"date-parts":[[1998,9]]}},{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:39:04Z","timestamp":1792791544475,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,8,8]],"date-time":"2017-08-08T00:00:00Z","timestamp":1502150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"GTF"},{"DOI":"10.13039\/100009655","name":"Sunovion","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009655","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Pearl Therapeutics"},{"DOI":"10.13039\/100009655","name":"Sunovion","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009655","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Forest"},{"name":"Meda"},{"name":"Verona"},{"name":"Theravance"},{"name":"Mylan"},{"name":"Innoviva"},{"DOI":"10.13039\/100004330","name":"GSK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009655","name":"Sunovion Pharmaceuticals Inc","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009655","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009655","name":"Sunovion Pharmaceuticals Inc","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009655","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.rmed.2017.07.011","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T18:30:48Z","timestamp":1500489048000},"page":"238-250","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Efficacy and safety of glycopyrrolate\/eFlow\u00ae CS (nebulized glycopyrrolate) in moderate-to-very-severe COPD: Results from the glycopyrrolate for obstructive lung disease via electronic nebulizer (GOLDEN) 3 and 4 randomized controlled trials"],"prefix":"10.1016","volume":"132","author":[{"given":"Edward","family":"Kerwin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James F.","family":"Donohue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Goodin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Tosiello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alistair","family":"Wheeler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary T.","family":"Ferguson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.rmed.2017.07.011_bib1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/resp.12660","article-title":"Global burden of COPD","volume":"21","author":"Lopez-Campos","year":"2016","journal-title":"Respirology"},{"key":"10.1016\/j.rmed.2017.07.011_bib2","series-title":"Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD)","author":"Global Strategy for the Diagnosis","year":"2017"},{"issue":"4","key":"10.1016\/j.rmed.2017.07.011_bib3","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1136\/thorax.55.4.289","article-title":"A\u00a0randomised controlled comparison of tiotropium and ipratropium in the treatment of chronic obstructive pulmonary disease. The Dutch Tiotropium Study Group","volume":"55","author":"van Noord","year":"2000","journal-title":"Thorax"},{"issue":"2","key":"10.1016\/j.rmed.2017.07.011_bib4","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1183\/09031936.02.00238702","article-title":"Improved health outcomes in patients with COPD during 1 yr's treatment with tiotropium","volume":"19","author":"Vincken","year":"2002","journal-title":"Eur. Respir. J."},{"issue":"2","key":"10.1016\/j.rmed.2017.07.011_bib5","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3132\/pcrj.2008.00024","article-title":"Comparison of tiotropium bromide and combined ipratropium\/salbutamol for the treatment of COPD: a UK General Practice Research Database 12-month follow-up study","volume":"17","author":"Griffin","year":"2008","journal-title":"Prim. Care Respir. J."},{"issue":"5","key":"10.1016\/j.rmed.2017.07.011_bib6","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1164\/ajrccm.164.5.2007006","article-title":"Inhaled formoterol dry powder versus ipratropium bromide in chronic obstructive pulmonary disease","volume":"164","author":"Dahl","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"9","key":"10.1016\/j.rmed.2017.07.011_bib7","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.rmed.2004.02.013","article-title":"Resource use and risk factors in high-cost exacerbations of COPD","volume":"98","author":"Oostenbrink","year":"2004","journal-title":"Respir. Med."},{"key":"10.1016\/j.rmed.2017.07.011_bib8","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/1465-9921-14-112","article-title":"COPD symptoms in the morning: impact, evaluation and management","volume":"14","author":"Roche","year":"2013","journal-title":"Respir. Res."},{"issue":"1","key":"10.1016\/j.rmed.2017.07.011_bib9","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1378\/chest.127.1.335","article-title":"Device selection and outcomes of aerosol therapy: evidence-based guidelines: American college of chest physicians\/American college of asthma, allergy, and immunology","volume":"127","author":"Dolovich","year":"2005","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.rmed.2017.07.011_bib10","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4212\/cjhp.v65i2.1118","article-title":"Evaluation of the use of inhaled medications by hospital inpatients with chronic obstructive pulmonary disease","volume":"65","author":"Batterink","year":"2012","journal-title":"Can. J. Hosp. Pharm."},{"issue":"3","key":"10.1016\/j.rmed.2017.07.011_bib11","first-page":"324","article-title":"Handling of inhaler devices in actual pulmonary practice: metered-dose inhaler versus dry powder inhalers","volume":"53","author":"Khassawneh","year":"2008","journal-title":"Respir. Care"},{"issue":"1","key":"10.1016\/j.rmed.2017.07.011_bib12","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1159\/000109374","article-title":"Dry powder inhalers: which factors determine the frequency of handling errors?","volume":"75","author":"Wieshammer","year":"2008","journal-title":"Respiration"},{"issue":"3","key":"10.1016\/j.rmed.2017.07.011_bib13","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1089\/089426803769017613","article-title":"Assessment of handling of inhaler devices in real life: an observational study in 3811 patients in primary care","volume":"16","author":"Molimard","year":"2003","journal-title":"J.\u00a0Aerosol Med."},{"issue":"10","key":"10.1016\/j.rmed.2017.07.011_bib14","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.arcped.2007.06.017","article-title":"Assessment of the handling of inhaler devices: an observational study of children in primary care","volume":"14","author":"Malot","year":"2007","journal-title":"Arch. Pediatr."},{"issue":"3","key":"10.1016\/j.rmed.2017.07.011_bib15","doi-asserted-by":"crossref","first-page":"371","DOI":"10.2147\/COPD.S3036","article-title":"Medication adherence issues in patients treated for COPD","volume":"3","author":"Restrepo","year":"2008","journal-title":"Int. J. Chron. Obstruct Pulmon Dis."},{"issue":"6","key":"10.1016\/j.rmed.2017.07.011_bib16","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1183\/09031936.00166410","article-title":"What the pulmonary specialist should know about the new inhalation therapies","volume":"37","author":"Laube","year":"2011","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.rmed.2017.07.011_bib17","first-page":"23","article-title":"Considerations for managing chronic obstructive pulmonary disease in the elderly","volume":"9","author":"Taffet","year":"2014","journal-title":"Clin. Interv. Aging"},{"key":"10.1016\/j.rmed.2017.07.011_bib18","first-page":"7","article-title":"Guiding principles for the use of nebulized long-acting beta2-agonists in patients with COPD: an expert panel consensus","volume":"4","author":"Wise","year":"2017","journal-title":"Chron. Obstruct Pulmon Dis. (Miami)"},{"key":"10.1016\/j.rmed.2017.07.011_bib19","first-page":"131","article-title":"Inhalation drug delivery devices: technology update","volume":"8","author":"Ibrahim","year":"2015","journal-title":"Med. Devices (Auckl)"},{"issue":"1","key":"10.1016\/j.rmed.2017.07.011_bib20","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3109\/15412555.2011.630047","article-title":"The role of nebulized therapy in the management of COPD: evidence and recommendations","volume":"9","author":"Dhand","year":"2012","journal-title":"COPD"},{"issue":"2","key":"10.1016\/j.rmed.2017.07.011_bib21","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1089\/jamp.2013.1038","article-title":"Comparison of dry powder versus nebulized beta-agonist in patients with COPD who have suboptimal peak inspiratory flow rate","volume":"27","author":"Mahler","year":"2014","journal-title":"J.\u00a0Aerosol Med. Pulm. Drug Deliv."},{"key":"10.1016\/j.rmed.2017.07.011_bib22","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.2147\/COPD.S114034","article-title":"A\u00a0review of nebulized drug delivery in COPD","volume":"11","author":"Tashkin","year":"2016","journal-title":"Int. J. Chron. Obstruct Pulmon Dis."},{"key":"10.1016\/j.rmed.2017.07.011_bib23","first-page":"A5472","article-title":"In-vitro characterization of the eFlow\u00ae Closed System (eFlow\u00ae CS) nebulizer with glycopyrrolate inhalation solution (SUN-101)","volume":"195","author":"Pham","year":"2017","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"4","key":"10.1016\/j.rmed.2017.07.011_bib24","doi-asserted-by":"crossref","first-page":"523","DOI":"10.3109\/15412555.2012.761960","article-title":"Inhaler devices for patients with COPD","volume":"10","author":"Fink","year":"2013","journal-title":"COPD"},{"issue":"9770","key":"10.1016\/j.rmed.2017.07.011_bib25","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/S0140-6736(10)60926-9","article-title":"Aerosol drug delivery: developments in device design and clinical use","volume":"377","author":"Dolovich","year":"2011","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.rmed.2017.07.011_bib26","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1053\/rmed.2001.1292","article-title":"Survey of patients' views of domiciliary nebuliser treatment for chronic lung disease","volume":"96","author":"Barta","year":"2002","journal-title":"Respir. Med."},{"issue":"7","key":"10.1016\/j.rmed.2017.07.011_bib27","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1513\/pats.200701-016FM","article-title":"Pharmacologic interventions chronic obstructive pulmonary disease: bronchodilators","volume":"4","author":"Hanania","year":"2007","journal-title":"Proc. Am. Thorac. Soc."},{"issue":"2","key":"10.1016\/j.rmed.2017.07.011_bib28","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/ageing\/afl174","article-title":"Inhaled therapy in elderly COPD patients; time for re-evaluation?","volume":"36","author":"Jarvis","year":"2007","journal-title":"Age Ageing"},{"key":"10.1016\/j.rmed.2017.07.011_bib29","series-title":"Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD)","author":"Global Strategy for the Diagnosis","year":"2014"},{"key":"10.1016\/j.rmed.2017.07.011_bib30","series-title":"Clinical Trials with Missing Data: a Guide for Practitioners","author":"O'Kelly","year":"2014"},{"issue":"11","key":"10.1016\/j.rmed.2017.07.011_bib31","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1136\/thorax.56.11.880","article-title":"Health status measurement in chronic obstructive pulmonary disease","volume":"56","author":"Jones","year":"2001","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2017.07.011_bib32","article-title":"Results of a pulmonologist survey regarding attitudes and practices with inhalation devices for COPD","volume":"193","author":"Braman","year":"2016","journal-title":"Am. J. Resp. Crit. Care"},{"issue":"2","key":"10.1016\/j.rmed.2017.07.011_bib33","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1089\/jam.2006.19.127","article-title":"Prescription bias and factors associated with improper use of inhalers","volume":"19","author":"Sestini","year":"2006","journal-title":"J.\u00a0Aerosol Med."},{"issue":"2","key":"10.1016\/j.rmed.2017.07.011_bib34","first-page":"174","article-title":"Performance comparison of nebulizer designs: constant-output, breath-enhanced, and dosimetric","volume":"49","author":"Rau","year":"2004","journal-title":"Resp. Care"}],"container-title":["Respiratory Medicine"],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095461111730210X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095461111730210X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:42:16Z","timestamp":1760614936000},"score":16.627977,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S095461111730210X"}},"issued":{"date-parts":[[2017,11]]},"references-count":34,"alternative-id":["S095461111730210X"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2017.07.011","ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy and safety of glycopyrrolate\/eFlow\u00ae CS (nebulized glycopyrrolate) in moderate-to-very-severe COPD: Results from the glycopyrrolate for obstructive lung disease via electronic nebulizer (GOLDEN) 3 and 4 randomized controlled trials","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2017.07.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]},{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T12:47:24Z","timestamp":1765975644245,"version":"3.41.0"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Anesthesiology"],"published-print":{"date-parts":[[1976,1,1]]},"DOI":"10.1097\/00000542-197601000-00005","type":"journal-article","created":{"date-parts":[[2006,9,19]],"date-time":"2006-09-19T08:46:10Z","timestamp":1158655570000},"page":"26-26","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["ATROPINE AND GLYCOPYRROLATE"],"prefix":"10.1097","volume":"44","member":"276","container-title":["Anesthesiology"],"language":"en","link":[{"URL":"http:\/\/pubs.asahq.org\/anesthesiology\/article-pdf\/44\/1\/26\/296154\/0000542-197601000-00005.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.lww.com\/00000542-197601000-00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T20:26:27Z","timestamp":1748031987000},"score":16.583128,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00000542-197601000-00005"}},"issued":{"date-parts":[[1976,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1976]]}},"URL":"https:\/\/doi.org\/10.1097\/00000542-197601000-00005","ISSN":["0003-3022"],"issn-type":[{"type":"print","value":"0003-3022"}],"published":{"date-parts":[[1976,1,1]]}},{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:38:46Z","timestamp":1773013126713,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1644,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1111\/j.1365-2885.2011.01272.x","type":"journal-article","created":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T15:18:10Z","timestamp":1299079090000},"page":"605-608","source":"Crossref","is-referenced-by-count":5,"title":["Pharmacokinetics of glycopyrrolate following intravenous administration in the horse"],"prefix":"10.1111","volume":"34","author":[{"given":"M. J.","family":"RUMPLER","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A.","family":"SAMS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"COLAHAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,3,2]]},"reference":[{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1023\/A:1020653922866","article-title":"Do plasma concentrations obtained from early arterial blood sampling improve pharmacokinetic\/pharmacodynamic modeling?","volume":"27","author":"Beaufort","year":"1999","journal-title":"Journal of Pharmacokinetics and Biopharmaceutics"},{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1023\/A:1018943613122","article-title":"Physiological parameters in laboratory animals and humans","volume":"10","author":"Davies","year":"1993","journal-title":"Pharmaceutical Research"},{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.2460\/ajvr.1998.59.11.1476","article-title":"Hepatic blood flow in horses during the recuperative period from maximal exercise","volume":"11","author":"Dyke","year":"1998","journal-title":"American Journal of Veterinary Research"},{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB4|cit4","volume-title":"Pharmacokinetic and Pharmacodynamic Data Analysis, Concepts and Applications","author":"Gabrielsson","year":"2007"},{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB5|cit5","doi-asserted-by":"crossref","DOI":"10.1201\/b14095","volume-title":"Pharmacokinetics","author":"Gibaldi","year":"1982"},{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB6|cit6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s002280100288","article-title":"Pharmacokinetic -pharmacodynamic model for the anticholinergic effect of glycopyrrolate","volume":"57","author":"Pentilla","year":"2001","journal-title":"European Journal of Clinical Pharmacology"},{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/j.1600-0773.1998.tb01456.x","article-title":"Pharmacokinetics and oral bioavailability of glycopyrrolate in children","volume":"83","author":"Rautakorpi","year":"1998","journal-title":"Pharmacology and Toxicology"},{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB8|cit8","unstructured":"Rumpler , M. Sams , R. Colahan , P. 2010a Method development and validation of glycopyrrolate in horse urine"},{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB9|cit9","unstructured":"Rumpler , M. Sams , R. Colahan , P. 2010b Validation of an LC\/MS\/MS method for quantification of glycopyrrolate in horse plasma Journal of Analytical Toxicology (in press)"},{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1365-2885.2004.00602.x","article-title":"Volumes of distribution","volume":"27","author":"Toutain","year":"2004","journal-title":"Journal of Veterinary Pharmacology and Therapeutics"},{"key":"10.1111\/j.1365-2885.2011.01272.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/BF01117450","article-title":"Application of Akaike\u2019s information criterion (AIC) in the evaluation of linear pharmacokinetic equations","volume":"6","author":"Yamaoka","year":"1978","journal-title":"Journal of Pharmacokinetics and Biopharmaceutics"}],"container-title":["Journal of Veterinary Pharmacology and Therapeutics"],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2885.2011.01272.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1365-2885.2011.01272.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T18:05:59Z","timestamp":1712253959000},"score":16.525827,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2885.2011.01272.x"}},"subtitle":["Glycopyrrolate pharmacokinetics in the horse"],"issued":{"date-parts":[[2011,3,2]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,12]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1365-2885.2011.01272.x","ISSN":["0140-7783"],"issn-type":[{"value":"0140-7783","type":"print"}],"published":{"date-parts":[[2011,3,2]]}},{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:55:47Z","timestamp":1761710147258,"version":"build-2065373602"},"reference-count":2,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T00:00:00Z","timestamp":1172102400000},"content-version":"vor","delay-in-days":9609,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[1980,11]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>The effect of intravenous administration of glycopyrrolate and atropine shortly before induction were compared in a double blind study in children. The study shows that glycopyrrolate, unlike atropine, administered before anaesthesia had little effect on heart rate. The heart rate changes at, and following, tracheal intubation were similar in both groups.<\/jats:p>","DOI":"10.1111\/j.1365-2044.1980.tb05044.x","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T20:53:20Z","timestamp":1172177600000},"page":"1068-1071","source":"Crossref","is-referenced-by-count":9,"title":["Glycopyrrolate in children"],"prefix":"10.1111","volume":"35","author":[{"given":"D. M.","family":"LAVIS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. N.","family":"LUNN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"ROSEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,2,22]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1978.tb08322.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-197603000-00010"}],"container-title":["Anaesthesia"],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2044.1980.tb05044.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2044.1980.tb05044.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T22:43:20Z","timestamp":1761691400000},"score":16.50452,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2044.1980.tb05044.x"}},"subtitle":["A comparison between the effects of glycopyrrolate and atropine administered before induction of anaesthesia"],"issued":{"date-parts":[[1980,11]]},"references-count":2,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1980,11]]}},"alternative-id":["10.1111\/j.1365-2044.1980.tb05044.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2044.1980.tb05044.x","archive":["Portico"],"ISSN":["0003-2409","1365-2044"],"issn-type":[{"type":"print","value":"0003-2409"},{"type":"electronic","value":"1365-2044"}],"published":{"date-parts":[[1980,11]]}},{"indexed":{"date-parts":[[2024,10,26]],"date-time":"2024-10-26T18:40:07Z","timestamp":1729968007499,"version":"3.28.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2024,10,26]]},"DOI":"10.7759\/cureus.72436","type":"journal-article","created":{"date-parts":[[2024,10,26]],"date-time":"2024-10-26T18:03:26Z","timestamp":1729965806000},"source":"Crossref","is-referenced-by-count":0,"title":["Combination of Intravenous Ondansetron and Intravenous Glycopyrrolate Versus Intravenous Ondansetron and Intramuscular Glycopyrrolate for Reduction of Post-spinal Hypotension in Cesaraen Section: A Randomized Double-Blinded Study"],"prefix":"10.7759","author":[{"given":"Sandip","family":"Baheti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharan","family":"Muruganantham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1186\/s42077-020-00121-7","article-title":"Anesthesia for cesarean delivery: general or regional anesthesia\u2014a systematic review","volume":"1","author":"Iddrisu M","year":"2021","unstructured":"Iddrisu M, Khan ZH. Anesthesia for cesarean delivery: general or regional anesthesia\u2014a systematic review. Ain-Shams J Anesthesiol 13. 2021, 1:10.1186\/s42077-020-00121-7","journal-title":"Ain-Shams J Anesthesiol 13"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-195903000-00001","article-title":"Hypotension during obstetrical anesthesia","volume":"20","author":"Kennedy RL","year":"1959","unstructured":"Kennedy RL, Friedman DL, Katcka DM, et al.. Hypotension during obstetrical anesthesia. Anesthesiology. 1959, 20:153-5. 10.1097\/00000542-195903000-00001","journal-title":"Anesthesiology"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002251.pub4","article-title":"Techniques for preventing hypotension during spinal anaesthesia for caesarean section","volume":"7","author":"Chooi C","year":"2020","unstructured":"Chooi C, Cox JJ, Lumb RS, et al.. Techniques for preventing hypotension during spinal anaesthesia for caesarean section. Cochrane Database Syst Rev. 2020, 7:CD002251. 10.1002\/14651858.CD002251.pub4","journal-title":"Cochrane Database Syst Rev"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.18203\/2349-3933.ijam20192255","article-title":"Ephedrine versus phenylephrine: effects on fetal acid-base status during spinal anesthesia for elective cesarean delivery","volume":"6","author":"Kumari P","year":"2019","unstructured":"Kumari P, Tahir S, Mir AA, et al.. Ephedrine versus phenylephrine: effects on fetal acid-base status during spinal anesthesia for elective cesarean delivery. Int J Adv Med. 2019, 6:871-5. 10.18203\/2349-3933.ijam20192255","journal-title":"Int J Adv Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200604000-00006","article-title":"Beta2-adrenoceptor genotype affects vasopressor requirements during spinal anesthesia for cesarean delivery","volume":"104","author":"Smiley RM","year":"2006","unstructured":"Smiley RM, Blouin JL, Negron M, Landau R. Beta2-adrenoceptor genotype affects vasopressor requirements during spinal anesthesia for cesarean delivery. Anesthesiology. 2006, 104:644-50. 10.1097\/00000542-200604000-00006","journal-title":"Anesthesiology"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002251.pub2","article-title":"Techniques for preventing hypotension during spinal anaesthesia for caesarean section","author":"Cyna AM","year":"2006","unstructured":"Cyna AM, Andrew M, Emmett RS, Middleton P, Simmons SW. Techniques for preventing hypotension during spinal anaesthesia for caesarean section. Cochrane Database Syst Rev. 2006, CD002251. 10.1002\/14651858.CD002251.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/75.3.262","article-title":"Volume preloading is not essential to prevent spinal-induced hypotension at caesarean section","volume":"75","author":"Jackson R","year":"1995","unstructured":"Jackson R, Reid JA, Thorburn J. Volume preloading is not essential to prevent spinal-induced hypotension at caesarean section. Br J Anaesth. 1995, 75:262-5. 10.1093\/bja\/75.3.262","journal-title":"Br J Anaesth"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199912000-00004","article-title":"Spinal hypotension associated with Cesarean section: will preload ever work?","volume":"91","author":"Rout C","year":"1999","unstructured":"Rout C, Rocke DA. Spinal hypotension associated with Cesarean section: will preload ever work?. Anesthesiology. 1999, 91:1565-7. 10.1097\/00000542-199912000-00004","journal-title":"Anesthesiology"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6661(199603\/04)5:2<79::AID-MFM6>3.0.CO;2-N","article-title":"Fetal effects of prophylactic ephedrine and maternal hypotension during regional anesthesia for cesarean section","volume":"5","author":"Shearer VE","year":"1996","unstructured":"Shearer VE, Ramin SM, Wallace DH, et al.. Fetal effects of prophylactic ephedrine and maternal hypotension during regional anesthesia for cesarean section. J Maternal Fetal Med. 1996, 5:79-84. 10.1002\/(SICI)1520-6661(199603\/04)5:2&lt;79::AID-MFM6&gt;3.0.CO;2-N","journal-title":"J Maternal Fetal Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200212000-00034","article-title":"Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery","volume":"97","author":"Cooper DW","year":"2002","unstructured":"Cooper DW, Carpenter M, Mowbray P, Desira WR, Ryall DM, Kokri MS. Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery. Anesthesiology. 2002, 97:1582-90. 10.1097\/00000542-200212000-00034","journal-title":"Anesthesiology"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X9202000408","article-title":"Prophylactic intramuscular ephedrine prior to caesarean section","volume":"20","author":"Rout CC","year":"1992","unstructured":"Rout CC, Rocke DA, Brijball R, Koovarjee RV. Prophylactic intramuscular ephedrine prior to caesarean section. Anaesth Intensive Care. 1992, 20:448-52. 10.1177\/0310057X9202000408","journal-title":"Anaesth Intensive Care"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200108000-00009","article-title":"Comparison of metaraminol and ephedrine infusions for maintaining arterial pressure during spinal anesthesia for elective cesarean section","volume":"95","author":"Ngan Kee WD","year":"2001","unstructured":"Ngan Kee WD, Lau TK, Khaw KS, Lee BB. Comparison of metaraminol and ephedrine infusions for maintaining arterial pressure during spinal anesthesia for elective cesarean section. Anesthesiology. 2001, 95:307-13. 10.1097\/00000542-200108000-00009","journal-title":"Anesthesiology"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/73.4.471","article-title":"Spinal anaesthesia for caesarean section: comparison of infusions of phenylephrine and ephedrine","volume":"73","author":"Hall PA","year":"1994","unstructured":"Hall PA, Bennett A, Wilkes MP, Lewis M. Spinal anaesthesia for caesarean section: comparison of infusions of phenylephrine and ephedrine. Br J Anaesth. 1994, 73:471-4. 10.1093\/bja\/73.4.471","journal-title":"Br J Anaesth"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3390\/ph15121588","article-title":"Ondansetron reduces the incidence of hypotension after spinal anaesthesia: a systematic review and meta-analysis","volume":"15","author":"Hou XM","year":"2022","unstructured":"Hou XM, Chen YJ, Lai L, Liu K, Shen QH. Ondansetron reduces the incidence of hypotension after spinal anaesthesia: a systematic review and meta-analysis. Pharmaceuticals (Basel). 2022, 15:10.3390\/ph15121588","journal-title":"Pharmaceuticals (Basel)"},{"key":"ref15","article-title":"Ondansetron Given Intravenously to Attenuate Hypotension and Bradycardia During Spinal Anesthesia in Cesarean Delivery: A Literature Review","author":"Denryter M","year":"2012","unstructured":"Denryter M, Lim P, Ponik J, Wilhelm T. Ondansetron Given Intravenously to Attenuate Hypotension and Bradycardia During Spinal Anesthesia in Cesarean Delivery: A Literature Review. Oakland University, Rochester; 2012."},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-013-0064-y","article-title":"Prophylactic glycopyrrolate reduces hypotensive responses in elderly patients during spinal anesthesia: a randomized controlled trial","volume":"61","author":"Hwang J","year":"2014","unstructured":"Hwang J, Min S, Kim C, Gil N, Kim E, Huh J. Prophylactic glycopyrrolate reduces hypotensive responses in elderly patients during spinal anesthesia: a randomized controlled trial. Can J Anaesth. 2014, 61:32-8. 10.1007\/s12630-013-0064-y","journal-title":"Can J Anaesth"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1983.tb12525.x","article-title":"Glycopyrrolate: pharmacology and clinical use","volume":"38","author":"Mirakhur RK","year":"1983","unstructured":"Mirakhur RK, Dundee JW. Glycopyrrolate: pharmacology and clinical use. Anaesthesia. 1983, 38:1195-204. 10.1111\/j.1365-2044.1983.tb12525.x","journal-title":"Anaesthesia"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000002274","article-title":"The effect of glycopyrrolate on the incidence of hypotension and vasopressor requirement during spinal anesthesia for cesarean delivery: a meta-analysis","volume":"126","author":"Patel SD","year":"2018","unstructured":"Patel SD, Habib AS, Phillips S, Carvalho B, Sultan P. The effect of glycopyrrolate on the incidence of hypotension and vasopressor requirement during spinal anesthesia for cesarean delivery: a meta-analysis. Anesth Analg. 2018, 126:552-8. 10.1213\/ANE.0000000000002274","journal-title":"Anesth Analg"},{"key":"ref19","article-title":"Evaluation of pre-emptive intramuscular glycopyrrolate in prevention of spinal anesthesia induced hypotension in elective cesarean sections","volume":"6","author":"Abhinaya M","year":"2019","unstructured":"Abhinaya M, Dinesh K. Evaluation of pre-emptive intramuscular glycopyrrolate in prevention of spinal anesthesia induced hypotension in elective cesarean sections. Indian J Anesth Analg. 2019, 6:705-11.","journal-title":"Indian J Anesth Analg"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.4103\/ija.ija_870_21","article-title":"Effect of prophylactic combination of glycopyrrolate, ondansetron, and ephedrine upon hypotension during obstetric spinal anaesthesia-a randomised controlled trial","volume":"65","author":"Vadhanan P","year":"2021","unstructured":"Vadhanan P, Kalyanasundaram C, Sundaram S, Rajendran I, Rajasekar P. Effect of prophylactic combination of glycopyrrolate, ondansetron, and ephedrine upon hypotension during obstetric spinal anaesthesia-a randomised controlled trial. Indian J Anaesth. 2021, 65:862-7. 10.4103\/ija.ija_870_21","journal-title":"Indian J Anaesth"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-022-01882-4","article-title":"Effect of glycopyrrolate on vasopressor requirements for non-elective cesarean section under spinal anesthesia: a randomized, double-blind, placebo-controlled trial","volume":"22","author":"Deshar R","year":"2022","unstructured":"Deshar R, Subedi A, Pokharel K, Sah BP, Prasad JN. Effect of glycopyrrolate on vasopressor requirements for non-elective cesarean section under spinal anesthesia: a randomized, double-blind, placebo-controlled trial. BMC Anesthesiol. 2022, 22:327. 10.1186\/s12871-022-01882-4","journal-title":"BMC Anesthesiol"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.4103\/ija.IJA_974_19","article-title":"The effect of ondansetron administration 20 minutes prior to spinal anaesthesia on haemodynamic status in patients undergoing elective caesarean section: a comparison between two different doses","volume":"64","author":"Samarah WK","year":"2020","unstructured":"Samarah WK, Alghanem SM, Bsisu IK, Rahman ZA, Guzu HA, Abufares BN. The effect of ondansetron administration 20 minutes prior to spinal anaesthesia on haemodynamic status in patients undergoing elective caesarean section: a comparison between two different doses. Indian J Anaesth. 2020, 64:954-9. 10.4103\/ija.IJA_974_19","journal-title":"Indian J Anaesth"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2011.08.002","article-title":"Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study","volume":"21","author":"Sahoo T","year":"2012","unstructured":"Sahoo T, SenDasgupta C, Goswami A, Hazra A. Reduction in spinal-induced hypotension with ondansetron in parturients undergoing caesarean section: a double-blind randomised, placebo-controlled study. Int J Obstet Anesth. 2012, 21:24-8. 10.1016\/j.ijoa.2011.08.002","journal-title":"Int J Obstet Anesth"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2044.2002.02326.x","article-title":"Glycopyrronium and hypotension following combined spinal-epidural anaesthesia for elective Caesarean section in women with relative bradycardia","volume":"57","author":"Rucklidge MW","year":"2002","unstructured":"Rucklidge MW, Durbridge J, Barnes PK, Yentis SM. Glycopyrronium and hypotension following combined spinal-epidural anaesthesia for elective Caesarean section in women with relative bradycardia. Anaesthesia. 2002, 57:4-8. 10.1046\/j.1365-2044.2002.02326.x","journal-title":"Anaesthesia"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1054\/ijoa.1999.0376","article-title":"The effect of prophylactic glycopyrrolate on maternal haemodynamics following spinal anaesthesia for elective caesarean section","volume":"9","author":"Yentis SM","year":"2000","unstructured":"Yentis SM, Jenkins CS, Lucas DN, Barnes PK. The effect of prophylactic glycopyrrolate on maternal haemodynamics following spinal anaesthesia for elective caesarean section. Int J Obstet Anesth. 2000, 9:156-9. 10.1054\/ijoa.1999.0376","journal-title":"Int J Obstet Anesth"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2013.03.008","article-title":"Haemodynamic effects of glycopyrrolate pre-treatment before phenylephrine infusion during spinal anaesthesia for caesarean delivery","volume":"22","author":"Ngan Kee WD","year":"2013","unstructured":"Ngan Kee WD, Lee SW, Khaw KS, Ng FF. Haemodynamic effects of glycopyrrolate pre-treatment before phenylephrine infusion during spinal anaesthesia for caesarean delivery. Int J Obstet Anesth. 2013, 22:179-87. 10.1016\/j.ijoa.2013.03.008","journal-title":"Int J Obstet Anesth"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/82.2.277","article-title":"Glycopyrrolate reduces nausea during spinal anaesthesia for caesarean section without affecting neonatal outcome","volume":"82","author":"Ure D","year":"1999","unstructured":"Ure D, James KS, McNeill M, Booth JV. Glycopyrrolate reduces nausea during spinal anaesthesia for caesarean section without affecting neonatal outcome. Br J Anaesth. 1999, 82:277-9. 10.1093\/bja\/82.2.277","journal-title":"Br J Anaesth"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.4097\/kjae.2012.62.1.35","article-title":"Comparison of hemodynamic changes between phenylephrine and combined phenylephrine and glycopyrrolate groups after spinal anesthesia for cesarean delivery","volume":"62","author":"Yoon HJ","year":"2012","unstructured":"Yoon HJ, Cho HJ, Lee IH, Jee YS, Kim SM. Comparison of hemodynamic changes between phenylephrine and combined phenylephrine and glycopyrrolate groups after spinal anesthesia for cesarean delivery. Korean J Anesthesiol. 2012, 62:35-9. 10.4097\/kjae.2012.62.1.35","journal-title":"Korean J Anesthesiol"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2010.12.008","article-title":"Prophylactic glycopyrrolate prevents bradycardia after spinal anesthesia for Cesarean section: a randomized, double-blinded, placebo-controlled prospective trial with heart rate variability correlation","volume":"23","author":"Chamchad D","year":"2011","unstructured":"Chamchad D, Horrow JC, Nakhamchik L, et al.. Prophylactic glycopyrrolate prevents bradycardia after spinal anesthesia for Cesarean section: a randomized, double-blinded, placebo-controlled prospective trial with heart rate variability correlation. J Clin Anesth. 2011, 23:361-6. 10.1016\/j.jclinane.2010.12.008","journal-title":"J Clin Anesth"},{"key":"ref30","article-title":"Effect of glycopyrrolate on the incidence of hypotension and vasopressor requirement during spinal anesthesia for cesarean delivery","volume":"5","author":"Ilapanda Swami DP","year":"2023","unstructured":"Ilapanda Swami DP, Guntareddi P, Kuraparthi J. Effect of glycopyrrolate on the incidence of hypotension and vasopressor requirement during spinal anesthesia for cesarean delivery. Int J Acad Med Pharm. 2023, 5:1322-1325.","journal-title":"Int J Acad Med Pharm"}],"container-title":["Cureus"],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/297876-combination-of-intravenous-ondansetron-and-intravenous-glycopyrrolate-versus-intravenous-ondansetron-and-intramuscular-glycopyrrolate-for-reduction-of-post-spinal-hypotension-in-cesaraen-section-a-randomized-double-blinded-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,26]],"date-time":"2024-10-26T18:03:28Z","timestamp":1729965808000},"score":16.500362,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/297876-combination-of-intravenous-ondansetron-and-intravenous-glycopyrrolate-versus-intravenous-ondansetron-and-intramuscular-glycopyrrolate-for-reduction-of-post-spinal-hypotension-in-cesaraen-section-a-randomized-double-blinded-study"}},"issued":{"date-parts":[[2024,10,26]]},"references-count":30,"URL":"https:\/\/doi.org\/10.7759\/cureus.72436","ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"published":{"date-parts":[[2024,10,26]]}},{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T18:06:54Z","timestamp":1767982014236,"version":"3.49.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Results in Chemistry"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.rechem.2025.102872","type":"journal-article","created":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T04:04:44Z","timestamp":1762574684000},"page":"102872","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Identification of degradation products formed by the interaction of glycopyrrolate and methylparaben in glycopyrrolate oral solution using spectral and chromatographic techniques"],"prefix":"10.1016","volume":"18","author":[{"given":"Sandeep","family":"Zokande","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavita","family":"Inamdar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Gosar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pramod","family":"Borade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tabrez","family":"Sheikh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rechem.2025.102872_bb0005","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.taap.2019.03.016","article-title":"Pharmacology, toxicology and clinical safety of glycopyrrolate","volume":"370","author":"Chabicovsky","year":"2019","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.rechem.2025.102872_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2024.116021","article-title":"A stability indicating RP-HPLC-UV assay method for the simultaneous determination of hydroquinone, tretinoin, hydrocortisone, butylated hydroxytoluene and parabens in pharmaceutical creams","volume":"242","author":"Khairy","year":"2024","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"3","key":"10.1016\/j.rechem.2025.102872_bb0015","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.jpba.2010.05.018","article-title":"LC-determination of five paraben preservatives in saliva and toothpaste samples using UV detection and a short monolithic column","volume":"53","author":"Zotou","year":"2010","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"4","key":"10.1016\/j.rechem.2025.102872_bb0020","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.jpba.2005.02.022","article-title":"A novel gradient HPLC method for simultaneous determination of ranitidine, methylparaben and propylparaben in oral liquid pharmaceutical formulation","volume":"38","author":"Kokoletsi","year":"2005","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"1","key":"10.1016\/j.rechem.2025.102872_bb0025","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jpba.2005.07.001","article-title":"Separation and determination of clotrimazole, methylparaben and propylparaben in pharmaceutical preparation by micellar electrokinetic chromatography","volume":"40","author":"Hamoudova","year":"2006","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"2","key":"10.1016\/j.rechem.2025.102872_bb0030","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jpba.2005.07.032","article-title":"Determination of ambroxol hydrochloride, methylparaben and benzoic acid in pharmaceutical preparations based on sequential injection technique coupled with monolithic column","volume":"40","author":"Satinsky","year":"2006","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"5","key":"10.1016\/j.rechem.2025.102872_bb0035","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S0731-7085(98)00297-0","article-title":"Howard, Dominic Ip, Determination of indinavir, potassium sorbate, methylparaben, and propylparaben in aqueous paediatric suspensions","volume":"19","author":"Dawn","year":"1999","journal-title":"J. Pharmaceutical Biomed. Anal."},{"issue":"2","key":"10.1016\/j.rechem.2025.102872_bb0040","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.jpba.2008.01.030","article-title":"Separation and determination of ketoprofen, methylparaben and propylparaben in pharmaceutical preparation by micellar electrokinetic chromatography","volume":"48","author":"Safra","year":"2008","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"2","key":"10.1016\/j.rechem.2025.102872_bb0045","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.jpba.2005.12.026","article-title":"Stability indicating simultaneous determination of domperidone (DP), methylparaben (MP) and propylparaben by high performance liquid chromatography (HPLC)","volume":"41","author":"Ali","year":"2006","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"2","key":"10.1016\/j.rechem.2025.102872_bb0050","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/jps.2600720227","article-title":"Simultaneous determination of acetaminophen, guaifenesin, pseudoephedrine, Pholcodine, and paraben preservatives in cough mixture by high-performance liquid chromatography","volume":"72","author":"Carnevale","year":"1983","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.rechem.2025.102872_bb0055","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.3390\/pharmaceutics16081018","article-title":"Long-term stability of glycopyrrolate oral solution galenic compound at different storage conditions","volume":"16","author":"Bellich","year":"2024","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.rechem.2025.102872_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2024.116256","article-title":"A drug\u2013excipient interaction impurity of bromhexine hydrochloride injection: structure and formation mechanism elucidation","volume":"247","author":"Zhou","year":"2024","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.rechem.2025.102872_bb0065","article-title":"Drug-excipient compatibility studies in formulation development: A case study with benznidazole and monoglycerides","volume":"235","author":"Saatkamp","year":"2023","journal-title":"J. Pharmaceutical Biomed. Analy."},{"issue":"3","key":"10.1016\/j.rechem.2025.102872_bb0070","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0731-7085(93)80202-C","article-title":"LC studies on the potential interaction of paraben preservatives with sorbitol and glycerol","volume":"11","author":"Thompson","year":"1993","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"3","key":"10.1016\/j.rechem.2025.102872_bb0075","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.jpba.2010.05.001","article-title":"Steen Honore Hansen, reaction between drug substances and pharmaceutical excipients: formation of esters between cetirizine and polyols","volume":"53","author":"He","year":"2010","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"7","key":"10.1016\/j.rechem.2025.102872_bb0080","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1002\/jps.10167","article-title":"Interaction of methylparaben preservative with selected sugars and sugar alcohols","volume":"91","author":"Ma","year":"2002","journal-title":"J. Pharm. Sci."},{"issue":"3","key":"10.1016\/j.rechem.2025.102872_bb0085","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1093\/chromsci\/40.3.170","article-title":"HPLC and LC-MS studies of the transesterification reaction of Methylparaben with twelve 3- to 6-carbon sugar alcohols and propylene glycol and the isomerization of the reaction products by acyl migration","volume":"40","author":"Ma","year":"2002","journal-title":"J. Chromatogr. Sci."},{"issue":"3","key":"10.1016\/j.rechem.2025.102872_bib96","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0731-7085(93)80202-C","article-title":"LC Studies on the Potential Interaction of Paraben Preservatives with Sorbitol and Glycerol","volume":"11","author":"Thompson","year":"1993","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"1","key":"10.1016\/j.rechem.2025.102872_bb0090","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/jps.2600840126","article-title":"Transesterification reactions of parabens (alkyl 4-Hydroxy benzoates) with polyols in aqueous solutions","volume":"84","author":"Hensel","year":"1995","journal-title":"J. Pharm. Sci."},{"issue":"2","key":"10.1016\/j.rechem.2025.102872_bb0095","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/jps.2600690214","article-title":"Effect of polyols on interaction of paraben preservatives with Polysorbate 80","volume":"69","author":"Blanchard","year":"1980","journal-title":"J. Pharm. Sci."}],"container-title":["Results in Chemistry"],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211715625008562?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211715625008562?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T21:00:16Z","timestamp":1767906016000},"score":16.423801,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211715625008562"}},"issued":{"date-parts":[[2025,11]]},"references-count":20,"alternative-id":["S2211715625008562"],"URL":"https:\/\/doi.org\/10.1016\/j.rechem.2025.102872","ISSN":["2211-7156"],"issn-type":[{"value":"2211-7156","type":"print"}],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of degradation products formed by the interaction of glycopyrrolate and methylparaben in glycopyrrolate oral solution using spectral and chromatographic techniques","name":"articletitle","label":"Article Title"},{"value":"Results in Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rechem.2025.102872","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"102872"},{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T17:28:38Z","timestamp":1755797318681,"version":"3.44.0"},"posted":{"date-parts":[[2025]]},"group-title":"SSRN","reference-count":20,"publisher":"Elsevier BV","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.2139\/ssrn.5396186","type":"posted-content","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T17:44:41Z","timestamp":1755539081000},"source":"Crossref","is-referenced-by-count":0,"title":["Identification of Degradation Products Formed by the Interaction of Glycopyrrolate and Methylparaben in Glycopyrrolate Oral Solution Using Spectral and Chromatographic Techniques"],"prefix":"10.2139","author":[{"given":"Sandeep  Shidu","family":"Zokande","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dr. Kavita","family":"Inamdar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dr. Amit","family":"Gosar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pramod","family":"Borade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tabrez","family":"Sheikh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"author":"References","key":"ref1"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.taap.2019.03.016","article-title":"Christoph Abels, Pharmacology, toxicology and clinical safety of glycopyrrolate","volume":"370","author":"Monika Chabicovsky","year":"2019","journal-title":"Toxicology and Applied Pharmacology"},{"key":"ref3","article-title":"A stability indicating RP-HPLC-UV assay method for the simultaneous determination of hydroquinone, tretinoin, hydrocortisone, butylated hydroxytoluene and parabens in pharmaceutical creams","volume":"242","author":"A Mostafa","year":"2024","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"3","key":"ref4","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.jpba.2010.05.018","article-title":"LC-determination of five paraben preservatives in saliva and toothpaste samples using UV detection and a short monolithic column","volume":"53","author":"Anastasia Zotou","year":"2010","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"4","key":"ref5","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.jpba.2005.02.022","article-title":"A novel gradient HPLC method for simultaneous determination of ranitidine, methylparaben and propylparaben in oral liquid pharmaceutical formulation","volume":"38","author":"Magdalene Xenou Kokoletsi","year":"2005","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jpba.2005.07.001","article-title":"Separation and determination of clotrimazole, methylparaben and propylparaben in pharmaceutical preparation by micellar electrokinetic chromatography","volume":"40","author":"Raf\ufffdfa Hamoudova","year":"2006","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"2","key":"ref7","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jpba.2005.07.032","article-title":"Determination of ambroxol hydrochloride, methylparaben and benzoic acid in pharmaceutical preparations based on sequential injection technique coupled with monolithic column","volume":"40","author":"Dalibor Satinsky","year":"2006","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"5","key":"ref8","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S0731-7085(98)00297-0","article-title":"Determination of indinavir, potassium sorbate, methylparaben, and propylparaben in aqueous paediatric suspensions","volume":"19","author":"Dawn M Kreuz","year":"1999","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"2","key":"ref9","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.jpba.2008.01.030","article-title":"Separation and determination of ketoprofen, methylparaben and propylparaben in pharmaceutical preparation by micellar electrokinetic chromatography","volume":"48","author":"Jiri Safra","year":"2008","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.jpba.2005.12.026","article-title":"Stability indicating simultaneous determination of domperidone (DP), methylparaben (MP) and propylparaben by high performance liquid chromatography (HPLC)","volume":"41","author":"Mohammed Shahid","year":"2006","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"2","key":"ref11","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/jps.2600720227","article-title":"Simultaneous Determination of Acetaminophen, Guaifenesin, Pseudoephedrine, Pholcodine, and Paraben Preservatives in Cough Mixture by High-Performance Liquid Chromatography","volume":"72","author":"Laura Carnevale","year":"1983","journal-title":"Journal of Pharmaceutical Sciences"},{"key":"ref12","article-title":"A drug-excipient interaction impurity of bromhexine hydrochloride injection: Structure and formation mechanism elucidation","volume":"247","author":"Min Zhou","year":"2024","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"key":"ref13","article-title":"Drug-excipient compatibility studies in formulation development: A case study with benznidazole and monoglycerides","volume":"235","author":"Rodrigo Henrique Saatkamp","year":"2023","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"3","key":"ref14","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0731-7085(93)80202-C","article-title":"LC studies on the potential interaction of paraben preservatives with sorbitol and glycerol","volume":"11","author":"Melanie J Thompson","year":"1993","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.jpba.2010.05.001","article-title":"Reaction between drug substances and pharmaceutical excipients: Formation of esters between cetirizine and polyols","volume":"53","author":"He Yu","year":"2010","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"7","key":"ref16","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1002\/jps.10167","article-title":"Interaction of methylparaben preservative with selected sugars and sugar alcohols","volume":"91","author":"Minhui Ma","year":"2002","journal-title":"Journal of Pharmaceutical Sciences"},{"issue":"3","key":"ref17","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1093\/chromsci\/40.3.170","article-title":"HPLC and LC-MS Studies of the Transesterification Reaction of Methylparaben with Twelve 3-to 6-carbon Sugar Alcohols and Propylene Glycol and the Isomerization of the Reaction Products by Acyl Migration","volume":"40","author":"Minhui Ma","year":"2002","journal-title":"Journal of Chromatographic Science"},{"issue":"3","key":"ref18","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0731-7085(93)80202-C","article-title":"LC Studies on the Potential Interaction of Paraben Preservatives with Sorbitol and Glycerol","volume":"11","author":"Melanie J Thompson","year":"1993","journal-title":"Journal of Pharmaceutical and Biomedical Analysis"},{"issue":"1","key":"ref19","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/jps.2600840126","article-title":"Transesterification Reactions of Parabens (alkyl 4-Hydroxy Benzoates) with Polyols in Aqueous Solutions","volume":"84","author":"A Hensel","year":"1995","journal-title":"Journal of Pharmaceutical Sciences"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/jps.2600690214","article-title":"Effect of Polyols on Interaction of Paraben Preservatives with Polysorbate 80","volume":"69","author":"James Blanchard","year":"1980","journal-title":"Journal of Pharmaceutical Sciences"}],"deposited":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T17:46:18Z","timestamp":1755539178000},"score":16.316326,"resource":{"primary":{"URL":"https:\/\/www.ssrn.com\/abstract=5396186"}},"issued":{"date-parts":[[2025]]},"references-count":20,"URL":"https:\/\/doi.org\/10.2139\/ssrn.5396186","published":{"date-parts":[[2025]]},"subtype":"preprint"},{"indexed":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T00:24:22Z","timestamp":1719966262291},"reference-count":1,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T00:00:00Z","timestamp":1719619200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T00:00:00Z","timestamp":1719619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reactions Weekly"],"DOI":"10.1007\/s40278-024-61720-3","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T15:26:40Z","timestamp":1719934000000},"page":"292-292","source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate"],"prefix":"10.1007","volume":"2014","member":"297","published-online":{"date-parts":[[2024,6,29]]},"reference":[{"key":"61720_CR1","doi-asserted-by":"crossref","unstructured":"Holbert K. Multiorgan Failure From Heat Stroke in a Person Taking Glycopyrrolate. American Journal of Respiratory and Critical Care Medicine 209:  abstr. A7329, Jan 2024 [abstract]","DOI":"10.1164\/ajrccm-conference.2024.209.1_MeetingAbstracts.A7329"}],"container-title":["Reactions Weekly"],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40278-024-61720-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40278-024-61720-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40278-024-61720-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T15:47:55Z","timestamp":1719935275000},"score":16.230217,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40278-024-61720-3"}},"subtitle":["Heat stroke"],"issued":{"date-parts":[[2024,6,29]]},"references-count":1,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["61720"],"URL":"https:\/\/doi.org\/10.1007\/s40278-024-61720-3","ISSN":["1179-2051"],"issn-type":[{"value":"1179-2051","type":"electronic"}],"published":{"date-parts":[[2024,6,29]]}},{"indexed":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T07:10:20Z","timestamp":1720163420663},"reference-count":1,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T00:00:00Z","timestamp":1720224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T00:00:00Z","timestamp":1720224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reactions Weekly"],"DOI":"10.1007\/s40278-024-62274-5","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T06:02:01Z","timestamp":1720159321000},"page":"191-191","source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate\/sugammadex"],"prefix":"10.1007","volume":"2015","member":"297","published-online":{"date-parts":[[2024,7,6]]},"reference":[{"key":"62274_CR1","doi-asserted-by":"crossref","unstructured":"Mignone D, et al. A RUDE AWAKENING: A CASE OF SUGAMMADEX CAUSING TRANSIENT CARDIOMYOPATHY MIMICKING STEMI. Journal of the American College of Cardiology 83 (Suppl.): 3618, No. 13, Apr 2024 [abstract]","DOI":"10.1016\/S0735-1097(24)05608-0"}],"container-title":["Reactions Weekly"],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40278-024-62274-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40278-024-62274-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40278-024-62274-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T06:46:19Z","timestamp":1720161979000},"score":16.118217,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40278-024-62274-5"}},"subtitle":["Transient cardiomyopathy"],"issued":{"date-parts":[[2024,7,6]]},"references-count":1,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,7]]}},"alternative-id":["62274"],"URL":"https:\/\/doi.org\/10.1007\/s40278-024-62274-5","ISSN":["1179-2051"],"issn-type":[{"value":"1179-2051","type":"electronic"}],"published":{"date-parts":[[2024,7,6]]}},{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T17:11:16Z","timestamp":1758042676921,"version":"3.44.0"},"reference-count":7,"publisher":"Elsevier","isbn-type":[{"type":"print","value":"9780080552323"}],"license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2007]]},"DOI":"10.1016\/b978-008055232-3.61835-5","type":"book-chapter","created":{"date-parts":[[2008,1,10]],"date-time":"2008-01-10T15:30:31Z","timestamp":1199979031000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate"],"prefix":"10.1016","author":[{"given":"John A.","family":"Davies","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/B978-008055232-3.61835-5_bb1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/j.1399-6576.1989.tb02956.x","article-title":"Glycopyrrolate: pharmacokinetics and some pharmacodynamic findings","volume":"33","author":"Ali-Melkkila","year":"1989","journal-title":"Acta Anaesthesiol. Scand."},{"key":"10.1016\/B978-008055232-3.61835-5_bb2","first-page":"131","article-title":"Pharmacodynamic evaluation of glycopyrrolate in animals","volume":"99","author":"Franko","year":"1962","journal-title":"Ann. New York Acad. Sci."},{"issue":"5","key":"10.1016\/B978-008055232-3.61835-5_bb3","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/bja\/74.5.549","article-title":"Atropine and glycopyrronium show similar binding patterns to M2 (cardiac) and M3 (submandibular gland) muscarinic receptor subtypes in the rat","volume":"74","author":"Gomez","year":"1995","journal-title":"Br. J. Anaesthes."},{"key":"10.1016\/B978-008055232-3.61835-5_bb11","series-title":"Therapeutic Drugs","first-page":"69","author":"Dollery","year":"1999"},{"key":"10.1016\/B978-008055232-3.61835-5_bb12","series-title":"The Merck Index","first-page":"802","author":"The Merck Index","year":"2001"},{"key":"10.1016\/B978-008055232-3.61835-5_bb13","series-title":"British National Formulary","first-page":"606","author":"British National Formulary","year":"2003"},{"key":"10.1016\/B978-008055232-3.61835-5_bb14","doi-asserted-by":"crossref","unstructured":"Mirakhur, Dundee, Glycopyrrolate: pharmacology and clinical use, Anaesthesia, 38 (1983) 1195\u20131294.","DOI":"10.1111\/j.1365-2044.1983.tb12525.x"}],"container-title":["xPharm: The Comprehensive Pharmacology Reference"],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:B9780080552323618355?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:B9780080552323618355?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T18:34:49Z","timestamp":1757615689000},"score":16.099237,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/B9780080552323618355"}},"issued":{"date-parts":[[2007]]},"ISBN":["9780080552323"],"references-count":7,"URL":"https:\/\/doi.org\/10.1016\/b978-008055232-3.61835-5","published":{"date-parts":[[2007]]}},{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T17:45:54Z","timestamp":1757612754224,"version":"3.44.0"},"reference-count":0,"publisher":"Elsevier","isbn-type":[{"type":"print","value":"9780323244855"}],"license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2016]]},"DOI":"10.1016\/b978-0-323-24485-5.00285-0","type":"book-chapter","created":{"date-parts":[[2016,9,4]],"date-time":"2016-09-04T06:16:26Z","timestamp":1472969786000},"page":"361-362","source":"Crossref","is-referenced-by-count":0,"title":["Glycopyrrolate"],"prefix":"10.1016","author":[{"given":"Mark G.","family":"Papich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","container-title":["Saunders Handbook of Veterinary Drugs"],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:B9780323244855002850?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:B9780323244855002850?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T15:44:58Z","timestamp":1757000698000},"score":16.02806,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/B9780323244855002850"}},"issued":{"date-parts":[[2016]]},"ISBN":["9780323244855"],"references-count":0,"URL":"https:\/\/doi.org\/10.1016\/b978-0-323-24485-5.00285-0","published":{"date-parts":[[2016]]}}],"items-per-page":20,"query":{"start-index":0,"search-terms":null}}}