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as compared to non-cancer individuals. An understanding of the mechanisms involved in diseasepathogenesis is paramount for prevention and treatment in cancer patients. Material and Methods: Total 120 blood samples were collected foranalysis randomly which were divided into two groups as A (leukemia patients) and B (normal individuals) having 60 in each. Both of thesegroups were further sub-divided (20 each) into three age groups (20-35, 36-50 and 51-70) A1, B1, A2, B2, A3, B3 respectively. Results: Asignificant (p&lt;0.05) increase in serum K+ level (hyperkalemia) was observed in cancer patients as compared to normal individuals having a nonsignificant (P&gt;0.05) interaction with the age limits. However a significant decrease (P&lt;0.05) in the levels of Mg2+, PO43- and Cl- (hypomagnesia,h pophosphatemia and hypochloridemia respectively) was recorded in group B as compared to group A having independency of age limits.Conclusion: Low serum Na+ (hyponatremia) was observed in Group B3 as compared to Group A3 (51-70) except the age limits (20-35 and 36-50) which showed a non significant interaction with this decreased level of sodium. 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