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Organisms and the environment may be exposed to mixtures rather than a single substance. Conducting toxicity tests for all possible combinations is impractical due to the enormous combinatorial complexity. This study highlights the development and application case studies of Mixture Risk Assessment Toolbox, a novel web-based platform that supports mixture risk assessment through the use of different prediction models and public databases. This integrated framework provides new functional values for assessors to easily screen and compare the toxicity of mixture products using different computational techniques and find strategic solutions to reduce the mixture toxicity in the product development process. The toolbox (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.mratoolbox.org\">https:\/\/www.mratoolbox.org<\/jats:ext-link>) includes four additive toxicity models: two conventional (Concentration Addition; and Independent Action) and two advanced (Generalized Concentration Addition; and Quantitative Structure\u2013Activity Relationship-based Two-Stage Prediction) models. 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As a result, they are widely utilized in the food industry as stabilizers and thickeners. Among galactomannan producing species, guar gum and locust bean gum are particularly important due to their economical relevance. Guar gum and locust bean gum are often adulterated with cellulose gums like xanthan gum and carboxymethyl cellulose (CMC). Adulteration of galactomannans with other gums may introduce uncertainties regarding functionality and complicate quality control, posing a potential problem for the food industry. Among the different techniques which have been used for determining and characterizing galactomannans, Fourier Transform Infrared Spectroscopy stands out. Especially when coupled to Attenuated Total Reflection (ATR), analyses are performed rapidly, with a minimum sample preparation, and without the need for solvent or previous extraction mechanisms. However, food is a very complex matrix that contains a high number of components which generate a multitude of spectral information and large data sets. Consequently, additional data processing tools such as chemometrics are needed to be able to draw useful information from spectra. Our goal in this work is to show how to optimize conditions for instrumental analysis by infrared spectroscopy of galactomannans and its constituent monomers and create a chemometric model where galactomannans could be differentiated as a single group. We successfully optimized the PCA model obtained after chemometric processing of infrared data through reducing dimensions by loadings selection.<\/jats:p>","DOI":"10.22616\/rrd.30.2024.013","type":"proceedings-article","created":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T20:54:27Z","timestamp":1734296067000},"page":"79-84","source":"Crossref","is-referenced-by-count":0,"title":["Chemometrics as an aid to quickly evaluate galactomannans through infrared spectroscopy"],"prefix":"10.22616","volume":"39","author":[{"name":"Tashkent Institute of Chemical Technology, Uzbekistan","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7284-518X","authenticated-orcid":false,"given":"Octavio","family":"Calvo-Gomez","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5369-7345","authenticated-orcid":false,"given":"Akbarali","family":"Ruzibayev","sequence":"additional","affiliation":[]},{"name":"Tashkent Institute of Chemical Technology, Uzbekistan","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0788-0165","authenticated-orcid":false,"given":"Shakhnozakhon","family":"Salijonova","sequence":"additional","affiliation":[]},{"name":"Tashkent Institute of Chemical Technology, Uzbekistan","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6954-9622","authenticated-orcid":false,"given":"Shakhnozakhon","family":"Gaipova","sequence":"additional","affiliation":[]},{"name":"Tashkent Institute of Chemical Technology, Uzbekistan","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3377-3483","authenticated-orcid":false,"given":"Sarvar","family":"Khodjaev","sequence":"additional","affiliation":[]},{"name":"Tashkent Institute of Chemical Technology, Uzbekistan","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7674-0393","authenticated-orcid":false,"given":"Zulfiyakhon","family":"Khakimova","sequence":"additional","affiliation":[]},{"name":"Tashkent Institute of Chemical Technology, Uzbekistan","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7442-3645","authenticated-orcid":false,"given":"Dilshod","family":"Rakhimov","sequence":"additional","affiliation":[]},{"name":"Tashkent Institute of Chemical Technology, Uzbekistan","sequence":"additional","affiliation":[]}],"member":"9905","published-online":{"date-parts":[[2024,11,27]]},"event":{"name":"Research for Rural Development 2024 : annual 30th international scientific conference","acronym":"RRD"},"container-title":["Research for Rural Development","Research for Rural Development 2024 : annual 30th international scientific conference proceedings"],"link":[{"URL":"https:\/\/lbtufb.lbtu.lv\/conference\/Research-for-Rural-Development\/2024\/LBTU_LatviaResRuralDev_30th_2024-79-84.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T20:54:31Z","timestamp":1734296071000},"score":12.118118,"resource":{"primary":{"URL":"https:\/\/lbtufb.lbtu.lv\/conference\/Research-for-Rural-Development\/2024\/LBTU_LatviaResRuralDev_30th_2024-79-84.pdf"}},"issued":{"date-parts":[[2024,11,27]]},"references-count":0,"URL":"https:\/\/doi.org\/10.22616\/rrd.30.2024.013","ISSN":["2255-923X"],"issn-type":[{"value":"2255-923X","type":"print"}],"published":{"date-parts":[[2024,11,27]]}},{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T11:40:59Z","timestamp":1723030859093},"reference-count":0,"publisher":"Science & Technology","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CE"],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:p>A technological process for low-temperature hydrolytic polymerization of caprolactam in a melt is being developed, which includes two stages: 1) prepolymer synthesis; 2) continuous combined drying\u2013demonomerization of the granulate. The first stage of the process was carried out at a temperature of 210-220\u00b0C. The synthesized prepolymer samples were investigated for the content of low molecular weight compounds and relative viscosity.<\/jats:p>","DOI":"10.31044\/1684-5811-2024-25-1-15-17","type":"journal-article","created":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T08:41:27Z","timestamp":1705653687000},"page":"15-17","source":"Crossref","is-referenced-by-count":0,"title":["Investigation of the properties of polyamide-6 prepolymer granulate"],"prefix":"10.31044","volume":"25","author":[{"name":"Ivanovo State University of Chemical Technology","sequence":"first","affiliation":[]},{"given":"M.V.","family":"Barannikov","sequence":"first","affiliation":[]},{"given":"V.S.","family":"Polyakov","sequence":"additional","affiliation":[]},{"name":"Ivanovo State University of Chemical Technology","sequence":"additional","affiliation":[]},{"given":"Yu.M.","family":"Bazarov","sequence":"additional","affiliation":[]},{"name":"Ivanovo State University of Chemical Technology","sequence":"additional","affiliation":[]},{"given":"G.V.","family":"Osipova","sequence":"additional","affiliation":[]},{"name":"Ivanovo State University of Chemical Technology","sequence":"additional","affiliation":[]},{"given":"K.A.","family":"Krivenko","sequence":"additional","affiliation":[]},{"name":"Ivanovo State University of Chemical Technology","sequence":"additional","affiliation":[]}],"member":"16041","published-online":{"date-parts":[[2024]]},"container-title":["Chemical Engineering"],"original-title":["\u0418\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u0441\u0432\u043e\u0439\u0441\u0442\u0432 \u0433\u0440\u0430\u043d\u0443\u043b\u044f\u0442\u0430 \u0444\u043e\u0440\u043f\u043e\u043b\u0438\u043c\u0435\u0440\u0430 \u043f\u043e\u043b\u0438\u0430\u043c\u0438\u0434\u0430-6"],"deposited":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T08:41:28Z","timestamp":1705653688000},"score":12.104631,"resource":{"primary":{"URL":"http:\/\/www.nait.ru\/journals\/number.php?p_number_id=3577"}},"issued":{"date-parts":[[2024]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024]]},"published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.31044\/1684-5811-2024-25-1-15-17","ISSN":["1684-5811"],"issn-type":[{"type":"print","value":"1684-5811"}],"published":{"date-parts":[[2024]]}},{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T23:30:00Z","timestamp":1723073400929},"reference-count":0,"publisher":"International Association for Statistical Education","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.52041\/srap.93210","type":"proceedings-article","created":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T22:40:39Z","timestamp":1655332839000},"source":"Crossref","is-referenced-by-count":0,"title":["Education in Statistics at the Higher Institute of Chemical Technology- Sofia"],"prefix":"10.52041","author":[{"name":"Higher Institute of Chemical Technology","sequence":"first","affiliation":[]},{"given":"Kamen","family":"Velev","sequence":"first","affiliation":[]},{"given":"Iunchev","family":"Vuchkov","sequence":"additional","affiliation":[]},{"name":"Higher Institute of Chemical Technology","sequence":"additional","affiliation":[]},{"given":"Hristos","family":"Iontchev","sequence":"additional","affiliation":[]},{"name":"Higher Institute of Chemical Technology","sequence":"additional","affiliation":[]}],"member":"28999","published-online":{"date-parts":[[1993,12,30]]},"event":{"name":"Proceedings of the First Scientific Meeting of the IASE"},"container-title":["Proceedings of the First Scientific Meeting of the IASE Satellite Conference"],"deposited":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T22:40:43Z","timestamp":1655332843000},"score":12.100573,"resource":{"primary":{"URL":"http:\/\/iase-web.org\/documents\/papers\/proc1993\/155-158rec.pdf?1402524982"}},"issued":{"date-parts":[[1993,12,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.52041\/srap.93210","published":{"date-parts":[[1993,12,30]]}},{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T12:12:59Z","timestamp":1648728779725},"reference-count":0,"publisher":"Wiley","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.1002\/(issn)1935-1836","type":"journal","created":{"date-parts":[[2018,8,5]],"date-time":"2018-08-05T11:40:24Z","timestamp":1533469224000},"source":"Crossref","is-referenced-by-count":0,"title":["Journal of Chemical Technology and Biotechnology. 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