This chapter focuses on quantitative genetics, which analyses the inheritance of complex traits. Complex traits are multifactorial: their expression is influenced by multiple genes and various environmental factors. Most complex traits exhibit continuous phenotypic variation and threshold traits exhibit just two phenotypes. Susceptibility to express a threshold trait is quantitative: it is determined by numerous genetic and environmental factors. The chapter also looks at the role of additive genes, the statistical analysis of continuous traits, heritability, human quantitative traits, and quantitative trait loci (QTL), which are genes that influence quantitative traits. Heritability values indicate the relative input of genetic and environmental factors in determining a phenotype.<\/p>","DOI":"10.1093\/hesc\/9780199694624.003.0005","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T11:19:23Z","timestamp":1694776763000},"source":"Crossref","is-referenced-by-count":0,"title":["Quantitative Genetics"],"prefix":"10.1093","author":[{"given":"Alison","family":"Thomas","sequence":"first","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["Thrive in Genetics"],"original-title":["Quantitative Genetics"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780199694624.001.0001\/isbn-9780199694624-book-part-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:08:41Z","timestamp":1707210521000},"score":10.576509,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780199694624.001.0001\/isbn-9780199694624-book-part-5"}},"issued":{"date-parts":[[2013,5,30]]},"ISBN":["9780199694624","9780191975851"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780199694624.003.0005","published":{"date-parts":[[2013,5,30]]}},{"indexed":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:37:05Z","timestamp":1715744225533},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780199694624","type":"print"},{"value":"9780191975851","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2013,5,30]]},"abstract":"
This chapter examines population genetics, which analyses the patterns of genetic variation shown by groups of individuals, i.e. by populations. This contrasts with the main concern of Mendelian genetics and, to a large extent, of quantitative genetics, as both focus on the genotype of individuals and the genotypes resulting from single mating. Population genetics explores the evolutionary processes that shape a population\u2019s genetic variation, i.e. mating systems, migration, mutation, population size, and selective forces. The chapter then considers how the analysis of genetic diversity in populations of endangered species helps formulate conservation policies. Ultimately, the genetic variation within and between different populations is described in terms of frequencies of alleles and resulting genotypes. The chapter looks at the Hardy\u2013Weinberg equilibrium, non-random mating, natural selection, and genetic drift.<\/p>","DOI":"10.1093\/hesc\/9780199694624.003.0013","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T07:19:59Z","timestamp":1694762399000},"source":"Crossref","is-referenced-by-count":0,"title":["Genetics of Populations"],"prefix":"10.1093","author":[{"given":"Alison","family":"Thomas","sequence":"first","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["Thrive in Genetics"],"original-title":["Genetics of Populations"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780199694624.001.0001\/isbn-9780199694624-book-part-13","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:08:46Z","timestamp":1707210526000},"score":10.549325,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780199694624.001.0001\/isbn-9780199694624-book-part-13"}},"issued":{"date-parts":[[2013,5,30]]},"ISBN":["9780199694624","9780191975851"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780199694624.003.0013","published":{"date-parts":[[2013,5,30]]}},{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T16:37:00Z","timestamp":1765384620157,"version":"3.46.0"},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780198834724","type":"print"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2025,6,20]]},"abstract":"
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\nAs we described in Chapter 4, eating disorders tend to run in families. One of the reasons for this is that the genes we inherit from our parents contribute to the risk of developing an eating disorder. Exactly how this works is...<\/p>","DOI":"10.1093\/wentk\/9780190926595.003.0018","type":"book-chapter","created":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T19:35:11Z","timestamp":1605209711000},"source":"Crossref","is-referenced-by-count":0,"title":["Genetics"],"prefix":"10.1093","author":[{"given":"B. Timothy","family":"Walsh","sequence":"first","affiliation":[]},{"given":"Evelyn","family":"Attia","sequence":"additional","affiliation":[]},{"given":"Deborah R.","family":"Glasofer","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2020,11,12]]},"container-title":["Eating Disorders"],"original-title":["Genetics"],"language":"en","deposited":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T23:40:46Z","timestamp":1657064446000},"score":10.126756,"resource":{"primary":{"URL":"https:\/\/whateveryoneneedstoknow.com\/view\/10.1093\/wentk\/9780190926595.001.0001\/isbn-9780190926595-book-part-18"}},"subtitle":["Emerging Knowledge About Genetics"],"issued":{"date-parts":[[2020,9,8]]},"ISBN":["9780190926595","9780197569757"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/wentk\/9780190926595.003.0018","published":{"date-parts":[[2020,9,8]]}},{"indexed":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:37:09Z","timestamp":1715744229441},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780199694624","type":"print"},{"value":"9780191975851","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2013,5,30]]},"abstract":"
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