{"status":"ok","message-type":"work-list","message-version":"1.0.0","message":{"facets":{},"total-results":4001621,"items":[{"indexed":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:39:52Z","timestamp":1715744392669},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780199270293","type":"print"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2012,3,15]]},"abstract":"

This chapter explores organic chemistry today and in the future. The most dramatic scientific developments involving organic chemistry at the beginning of the 21st century are new methods in medicine from collaborations between organic chemists and biologists. Progress is slow but secure across a whole range of diseases long thought impregnable to treatment. The chapter looks at two medical developments, both battles pitting chemists against viruses: the synthesis of indinavir and oseltamivir. Not all organic chemists can be involved in such exciting projects as the launching of a lifesaving antiviral drug. Some most certainly have to be: resistant bacteria are fast catching up with the current range of antibiotics, and it is teams of organic chemists, in conjunction with biologists, who will be able to erect the next line of defence against these infections.<\/p>","DOI":"10.1093\/hesc\/9780199270293.003.0043","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T06:56:17Z","timestamp":1694760977000},"source":"Crossref","is-referenced-by-count":0,"title":["Organic chemistry today"],"prefix":"10.1093","author":[{"given":"Jonathan","family":"Clayden","sequence":"first","affiliation":[]},{"given":"Nick","family":"Greeves","sequence":"additional","affiliation":[]},{"given":"Stuart","family":"Warren","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["Organic Chemistry"],"original-title":["Organic chemistry today"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-43","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:02:35Z","timestamp":1707210155000},"score":16.437216,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-43"}},"issued":{"date-parts":[[2012,3,15]]},"ISBN":["9780199270293"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780199270293.003.0043","published":{"date-parts":[[2012,3,15]]}},{"indexed":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:40:26Z","timestamp":1715744426699},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780199270293","type":"print"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2012,3,15]]},"abstract":"

This chapter provides an overview of organic chemistry. Organic chemistry started as the chemistry of life, which was once thought to be different from the chemistry in the laboratory. Then it became the chemistry of carbon compounds, especially those found in coal. But now, it is both. It is the chemistry of the compounds formed by carbon and other elements such as those found in living things, in the products of living things, and other places where carbon is found. The chapter then looks at organic compounds before considering the relationship between organic chemistry and industry. It also presents the periodic table.<\/p>","DOI":"10.1093\/hesc\/9780199270293.003.0001","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T13:33:24Z","timestamp":1694784804000},"source":"Crossref","is-referenced-by-count":0,"title":["What is organic chemistry?"],"prefix":"10.1093","author":[{"given":"Jonathan","family":"Clayden","sequence":"first","affiliation":[]},{"given":"Nick","family":"Greeves","sequence":"additional","affiliation":[]},{"given":"Stuart","family":"Warren","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["Organic Chemistry"],"original-title":["What is organic chemistry?"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:01:47Z","timestamp":1707210107000},"score":16.281527,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-1"}},"issued":{"date-parts":[[2012,3,15]]},"ISBN":["9780199270293"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780199270293.003.0001","published":{"date-parts":[[2012,3,15]]}},{"indexed":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:40:11Z","timestamp":1715744411809},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780199270293","type":"print"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2012,3,15]]},"abstract":"

This chapter assesses the organic chemistry of life. Life runs on chemistry, and the chemical side of biology is fascinating for that reason alone. Nucleic acids contain the genetic information of every organism, and they control the synthesis of proteins. Proteins are partly structural, as in connective tissue, and partly functional, as in enzymes, the catalysts for biological reactions. Meanwhile, sugars and lipids used to be thought of as the poor relations of the other two, storing energy and building membranes, but it is now clear that they also have a vital part to play in recognition and transport. The chemistry common to all living things is known as primary metabolism. The chapter also looks at mechanisms in biological chemistry.<\/p>","DOI":"10.1093\/hesc\/9780199270293.003.0042","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T12:51:57Z","timestamp":1694782317000},"source":"Crossref","is-referenced-by-count":0,"title":["Organic chemistry of life"],"prefix":"10.1093","author":[{"given":"Jonathan","family":"Clayden","sequence":"first","affiliation":[]},{"given":"Nick","family":"Greeves","sequence":"additional","affiliation":[]},{"given":"Stuart","family":"Warren","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["Organic Chemistry"],"original-title":["Organic chemistry of life"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-42","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:02:34Z","timestamp":1707210154000},"score":16.233725,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-42"}},"issued":{"date-parts":[[2012,3,15]]},"ISBN":["9780199270293"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780199270293.003.0042","published":{"date-parts":[[2012,3,15]]}},{"indexed":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T23:14:46Z","timestamp":1717110886048},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780199693276","type":"print"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2013,11,7]]},"abstract":"

This chapter looks at the reactions used in organic synthesis. It defines organic synthesis as the directed preparation of a sought compound usually, but not invariably, with some structural complexity from simple, readily available compounds. The chapter also develops the concept of retrosynthesis further and examines how to identify routes for syntheses of target compounds by applying organic reactions. Organic synthesis is one of the ultimate goals of organic chemistry and provides limitless opportunities to challenge the scientific imagination. The chapter then proceeds to discuss the synthons and the corresponding reagents as well as the reaction selectivity. Finally, the chapter elaborates on linear and convergent strategies, and presents some examples of organic synthesis.<\/p>","DOI":"10.1093\/hesc\/9780199693276.003.0023","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T07:24:35Z","timestamp":1694762675000},"source":"Crossref","is-referenced-by-count":1,"title":["Organic Synthesis"],"prefix":"10.1093","author":[{"given":"Tadashi","family":"Okuyama","sequence":"first","affiliation":[]},{"given":"Howard","family":"Maskill","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["Organic Chemistry"],"original-title":["Organic Synthesis"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780199693276.001.0001\/isbn-9780199693276-book-part-23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:08:22Z","timestamp":1707210502000},"score":16.010643,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780199693276.001.0001\/isbn-9780199693276-book-part-23"}},"issued":{"date-parts":[[2013,11,7]]},"ISBN":["9780199693276"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780199693276.003.0023","published":{"date-parts":[[2013,11,7]]}},{"indexed":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:40:03Z","timestamp":1715744403865},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780199270293","type":"print"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2012,3,15]]},"abstract":"

This chapter discusses three of the most important elements in the periodic table: sulfur, phosphorus, and silicon. They all form stable organic compounds and play nearly as important roles in organic chemistry as oxygen, nitrogen, and the halogens. Silicon forms tetrahedral silanes, rather like alkanes, but also forms stable five-valent anions. Phosphorus forms phosphines, rather like amines, but also tetrahedral phosphine oxides. Meanwhile, sulfur can have any coordination number from zero to seven, forming sulfides, like ethers, and tetrahedral sulfones with six bonds to sulfur. The chapter then looks at sulfur-stabilized anions, sulfur salts, and sulfonium ylids. It also considers allyl silanes as nucleophiles, before studying the selective synthesis of alkenes.<\/p>","DOI":"10.1093\/hesc\/9780199270293.003.0027","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T11:25:22Z","timestamp":1694777122000},"source":"Crossref","is-referenced-by-count":0,"title":["Sulfur, silicon, and phosphorus in organic chemistry"],"prefix":"10.1093","author":[{"given":"Jonathan","family":"Clayden","sequence":"first","affiliation":[]},{"given":"Nick","family":"Greeves","sequence":"additional","affiliation":[]},{"given":"Stuart","family":"Warren","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["Organic Chemistry"],"original-title":["Sulfur, silicon, and phosphorus in organic chemistry"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-27","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:02:19Z","timestamp":1707210139000},"score":15.939359,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-27"}},"issued":{"date-parts":[[2012,3,15]]},"ISBN":["9780199270293"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780199270293.003.0027","published":{"date-parts":[[2012,3,15]]}},{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T05:55:40Z","timestamp":1649051740342},"reference-count":0,"publisher":"Elsevier","content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[1990]]},"DOI":"10.1016\/b978-0-444-88345-2.50003-1","type":"book-chapter","created":{"date-parts":[[2013,9,26]],"date-time":"2013-09-26T08:41:36Z","timestamp":1380184896000},"page":"V-VI","source":"Crossref","is-referenced-by-count":0,"title":["Studies in Organic Chemistry"],"prefix":"10.1016","member":"78","container-title":["Studies in Organic Chemistry","Organic Chemistry in Action - The Design of Organic Synthesis"],"deposited":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T13:51:56Z","timestamp":1539352316000},"score":15.880572,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/B9780444883452500031"}},"issued":{"date-parts":[[1990]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1016\/b978-0-444-88345-2.50003-1","ISSN":["0165-3253"],"issn-type":[{"value":"0165-3253","type":"print"}],"published":{"date-parts":[[1990]]}},{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T21:57:44Z","timestamp":1773179864960,"version":"3.50.1"},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780199270293","type":"print"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2012,3,15]]},"abstract":"

This chapter discusses the process of interpreting organic structures and drawing organic molecules. Organic chemistry is the study of compounds that contain carbon. Nearly all organic compounds also contain hydrogen; most also contain oxygen, nitrogen, or other elements. Organic chemistry concerns itself with the way in which these atoms are bonded together into stable molecular structures, and the way in which these structures change in the course of chemical reactions. The chapter then looks at hydrocarbon frameworks and functional groups. It also considers how carbon atoms carrying functional groups can be classified based on oxidation levels, before explaining the process of naming compounds.<\/p>","DOI":"10.1093\/hesc\/9780199270293.003.0002","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T12:45:52Z","timestamp":1694781952000},"source":"Crossref","is-referenced-by-count":4,"title":["Organic structures"],"prefix":"10.1093","author":[{"given":"Jonathan","family":"Clayden","sequence":"first","affiliation":[]},{"given":"Nick","family":"Greeves","sequence":"additional","affiliation":[]},{"given":"Stuart","family":"Warren","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["Organic Chemistry"],"original-title":["Organic structures"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:01:47Z","timestamp":1707210107000},"score":15.791571,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-2"}},"issued":{"date-parts":[[2012,3,15]]},"ISBN":["9780199270293"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780199270293.003.0002","published":{"date-parts":[[2012,3,15]]}},{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T09:11:20Z","timestamp":1648717880121},"reference-count":0,"publisher":"Hindawi Limited","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.5402\/oc","type":"journal","created":{"date-parts":[[2012,10,25]],"date-time":"2012-10-25T08:32:34Z","timestamp":1351153954000},"source":"Crossref","is-referenced-by-count":0,"title":["ISRN Organic Chemistry"],"prefix":"10.5402","member":"98","language":"en","deposited":{"date-parts":[[2012,10,25]],"date-time":"2012-10-25T08:32:34Z","timestamp":1351153954000},"score":15.789845,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/isrn\/oc\/"}},"short-title":["ISRN Organic Chemistry"],"issued":{"date-parts":[[null]]},"references-count":0,"URL":"https:\/\/doi.org\/10.5402\/oc","ISSN":["2090-5157"],"issn-type":[{"value":"2090-5157","type":"electronic"}]},{"indexed":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:40:19Z","timestamp":1715744419964},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780199270293","type":"print"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2012,3,15]]},"abstract":"

This chapter evaluates organic reactions. It looks at the behaviour of organic molecules: why some react together and some do not, and how to understand reactivity in terms of charges, orbitals, and the movement of electrons. The chapter also introduces a device for representing the detailed movement of electrons\u2014the mechanism of the reaction\u2014called the curly arrow. The best reactions are ones in which the energies of the interacting orbitals are similar in energy. What does this mean for nucleophiles and electrophiles? In general, filled orbitals tend to be low in energy. Conversely, empty orbitals tend to be high in energy. As such, the best interaction is likely to be between the highest in energy of all the filled orbitals\u2014the \u2018highest occupied molecular orbital\u2019 or HOMO for short\u2014and the lowest in energy of all of the unfilled orbitals\u2014the \u2018lowest unoccupied molecular orbital\u2019 or LUMO.<\/p>","DOI":"10.1093\/hesc\/9780199270293.003.0005","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T13:28:35Z","timestamp":1694784515000},"source":"Crossref","is-referenced-by-count":0,"title":["Organic reactions"],"prefix":"10.1093","author":[{"given":"Jonathan","family":"Clayden","sequence":"first","affiliation":[]},{"given":"Nick","family":"Greeves","sequence":"additional","affiliation":[]},{"given":"Stuart","family":"Warren","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["Organic Chemistry"],"original-title":["Organic reactions"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:01:49Z","timestamp":1707210109000},"score":15.775276,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780199270293.001.0001\/isbn-9780199270293-book-part-5"}},"issued":{"date-parts":[[2012,3,15]]},"ISBN":["9780199270293"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780199270293.003.0005","published":{"date-parts":[[2012,3,15]]}},{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T19:18:59Z","timestamp":1648581539768},"reference-count":0,"publisher":"Hindawi Limited","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.1155\/5903","type":"journal","created":{"date-parts":[[2013,11,17]],"date-time":"2013-11-17T07:19:28Z","timestamp":1384672768000},"source":"Crossref","is-referenced-by-count":0,"title":["Organic Chemistry International"],"prefix":"10.1155","member":"98","language":"en","deposited":{"date-parts":[[2013,11,17]],"date-time":"2013-11-17T07:19:28Z","timestamp":1384672768000},"score":15.720015,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/oci\/"}},"short-title":["Organic Chemistry International"],"issued":{"date-parts":[[null]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1155\/5903","ISSN":["2090-2018"],"issn-type":[{"value":"2090-2018","type":"electronic"}]},{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T22:11:48Z","timestamp":1757628708298,"version":"3.44.0"},"reference-count":0,"publisher":"Elsevier","isbn-type":[{"type":"print","value":"9780080359410"}],"license":[{"start":{"date-parts":[[1994,1,1]],"date-time":"1994-01-01T00:00:00Z","timestamp":757382400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1994,1,1]],"date-time":"1994-01-01T00:00:00Z","timestamp":757382400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[1994]]},"DOI":"10.1016\/b978-0-08-035941-0.50001-x","type":"book-chapter","created":{"date-parts":[[2013,8,30]],"date-time":"2013-08-30T18:45:29Z","timestamp":1377888329000},"page":"i","source":"Crossref","is-referenced-by-count":0,"title":["Tetrahedron Organic Chemistry Series"],"prefix":"10.1016","member":"78","container-title":["Tetrahedron Organic Chemistry Series","Enzymes in Synthetic Organic Chemistry"],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:B978008035941050001X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:B978008035941050001X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T11:07:02Z","timestamp":1757502422000},"score":15.699892,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/B978008035941050001X"}},"issued":{"date-parts":[[1994]]},"ISBN":["9780080359410"],"references-count":0,"URL":"https:\/\/doi.org\/10.1016\/b978-0-08-035941-0.50001-x","ISSN":["1460-1567"],"issn-type":[{"type":"print","value":"1460-1567"}],"published":{"date-parts":[[1994]]}},{"indexed":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:35:58Z","timestamp":1715744158061},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780198851295","type":"print"},{"value":"9780191992506","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2020,3,3]]},"abstract":"

Regioselectivity<\/p>\n

A regioselective<\/bold> reaction produces more of one isomer than another. We haven\u2019t looked at the hydration (addition of water) of alkenes, but this doesn\u2019t matter. Each isomer is produced by the same<\/bold> reaction but at a different end of the...<\/p>","DOI":"10.1093\/hesc\/9780198851295.003.0065","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T07:55:01Z","timestamp":1694764501000},"source":"Crossref","is-referenced-by-count":0,"title":["Selectivity in Organic Chemistry\u2014Regioselectivity"],"prefix":"10.1093","author":[{"given":"Mark C.","family":"Elliott","sequence":"first","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["How to Succeed in Organic Chemistry"],"original-title":["Selectivity in Organic Chemistry\u2014Regioselectivity"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780198851295.001.0001\/isbn-9780198851295-book-part-65","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T08:58:46Z","timestamp":1707209926000},"score":15.695564,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780198851295.001.0001\/isbn-9780198851295-book-part-65"}},"issued":{"date-parts":[[2020,3,3]]},"ISBN":["9780198851295","9780191992506"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780198851295.003.0065","published":{"date-parts":[[2020,3,3]]}},{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T08:15:40Z","timestamp":1648628140588},"reference-count":0,"publisher":"Hindawi Limited","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.1155\/9141","type":"journal","created":{"date-parts":[[2017,12,10]],"date-time":"2017-12-10T11:53:29Z","timestamp":1512906809000},"source":"Crossref","is-referenced-by-count":0,"title":["ISRN Organic Chemistry"],"prefix":"10.1155","member":"98","language":"en","deposited":{"date-parts":[[2017,12,10]],"date-time":"2017-12-10T11:53:29Z","timestamp":1512906809000},"score":15.677399,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/archive\/"}},"short-title":["ISRN Organic Chemistry"],"issued":{"date-parts":[[null]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1155\/9141","ISSN":["2090-5157"],"issn-type":[{"value":"2090-5157","type":"electronic"}]},{"indexed":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:35:42Z","timestamp":1715744142369},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780198851295","type":"print"},{"value":"9780191992506","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2020,3,3]]},"abstract":"

Introduction<\/p>\n

Before we start, let\u2019s establish one thing. There is nothing<\/bold> special about stereoselectivity. It follows the same \u2018rules\u2019 as the other types of selectivity.<\/p>\n

We are going to do a lot more work in this chapter, because stereoselectivity often causes problems. In the early...<\/p>","DOI":"10.1093\/hesc\/9780198851295.003.0066","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T07:17:22Z","timestamp":1694762242000},"source":"Crossref","is-referenced-by-count":0,"title":["Selectivity in Organic Chemistry\u2014Stereoselectivity"],"prefix":"10.1093","author":[{"given":"Mark C.","family":"Elliott","sequence":"first","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["How to Succeed in Organic Chemistry"],"original-title":["Selectivity in Organic Chemistry\u2014Stereoselectivity"],"language":"en","link":[{"URL":"https:\/\/www.oxfordsciencetrove.com\/display\/10.1093\/hesc\/9780198851295.001.0001\/isbn-9780198851295-book-part-66","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T08:58:47Z","timestamp":1707209927000},"score":15.661949,"resource":{"primary":{"URL":"https:\/\/www.oxfordsciencetrove.com\/view\/10.1093\/hesc\/9780198851295.001.0001\/isbn-9780198851295-book-part-66"}},"issued":{"date-parts":[[2020,3,3]]},"ISBN":["9780198851295","9780191992506"],"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/hesc\/9780198851295.003.0066","published":{"date-parts":[[2020,3,3]]}},{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T19:58:35Z","timestamp":1648929515777},"reference-count":0,"publisher":"Elsevier","content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[1970]]},"DOI":"10.1016\/b978-0-12-676950-0.50001-8","type":"book-chapter","created":{"date-parts":[[2012,12,4]],"date-time":"2012-12-04T04:06:20Z","timestamp":1354593980000},"page":"ii","source":"Crossref","is-referenced-by-count":0,"title":["Organic Chemistry"],"prefix":"10.1016","member":"78","container-title":["Organic Chemistry","The Chemistry of Indoles"],"deposited":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T16:52:59Z","timestamp":1540054379000},"score":15.629467,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/B9780126769500500018"}},"issued":{"date-parts":[[1970]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1016\/b978-0-12-676950-0.50001-8","ISSN":["0078-611X"],"issn-type":[{"value":"0078-611X","type":"print"}],"published":{"date-parts":[[1970]]}},{"indexed":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:36:16Z","timestamp":1715744176412},"reference-count":0,"publisher":"Oxford University Press","isbn-type":[{"value":"9780198851295","type":"print"},{"value":"9780191992506","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2020,3,3]]},"abstract":"

Chemoselectivity<\/p>\n

Chemoselectivity is observed where one outcome is preferred in a reaction.<\/p>\n

There are actually two definitions that we need to consider.<\/p>\n

\n A chemoselective reaction is one in which one functional group reacts preferentially to another in a particular reaction.<\/italic>\n <\/p>\n

A chemoselective<\/bold> reaction...<\/p>","DOI":"10.1093\/hesc\/9780198851295.003.0064","type":"book-chapter","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T11:36:52Z","timestamp":1694777812000},"source":"Crossref","is-referenced-by-count":0,"title":["Selectivity in Organic Chemistry\u2014Chemoselectivity"],"prefix":"10.1093","author":[{"given":"Mark C.","family":"Elliott","sequence":"first","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2023,8,31]]},"container-title":["How to Succeed in Organic Chemistry"],"original-title":["Selectivity in Organic 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