{"status":"ok","message-type":"work-list","message-version":"1.0.0","message":{"facets":{},"total-results":116218,"items":[{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T08:22:24Z","timestamp":1772266944000,"version":"3.50.1"},"reference-count":0,"publisher":"eLife Sciences Publications, Ltd","content-domain":{"domain":[],"crossmark-restriction":false},"DOI":"10.7554\/elife.45590.017","type":"component","created":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T08:00:28Z","timestamp":1568016028000},"source":"Crossref","is-referenced-by-count":0,"title":["Figure 5\u2014figure supplement 1. In vivo extracellular recordings of PC complex spike activity in TRPC3Mwk\/-, pcp2Cre;TRPC3fl\/fl mice, pcp2Cre;TRPC3fl\/fl;EAAT4GFP\/- and pcp2CreERT2;TRPC3fl\/fl mice."],"prefix":"10.7554","member":"4374","deposited":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T08:00:40Z","timestamp":1568016040000},"score":19.141575,"resource":{"primary":{"URL":"https:\/\/elifesciences.org\/articles\/45590\/figures#fig5s1"}},"subtitle":["(A\u2013C) CV for complex spikes (CS-CV) of PCs recorded in TRPC3Mwk\/- mice, were significantly increased in both Z\u2013 and Z+ PCs.\u00a0CS-CV2 and CF-pause in both Z\u2013 and Z+ PCs of TRPC3Mwk\/- mice were unaffected, compared with those of littermate controls. (D\u2013F), In pcp2Cre;TRPC3fl\/fl mice, CS-CV, CS-CV2 in both Z\u2013 and Z+ PCs do not differ from littermate controls. However, CF-pause was significant longer Z\u2013 PC (F), left), but unaffected in Z+ PCs. (G\u2013I) In pcp2Cre;TRPC3fl\/fl;EAAT4GFP\/- mice, all parameters for Z\u2013 PCs, including CS-CV, CS-CV2 and CF-pause, were significantly increased compared to those of littermate controls. However, there was no change in those features of the Z+ PCs. (J\u2013L), After tamoxifen-induced TRPC3 ablation, PCs in pcp2CreERT2;TRPC3fl\/fl mice showed no significant differences in CS-CV, CS-CV2 and CF-pause in Z\u2013 or Z+ PCs, as compared with those of littermate controls that were also injected with tamoxifen. Error bars denote s.d.. * equals p&lt;0.05, **p&lt;0.01 and ***p&lt;0.001."],"issued":{"date-parts":[[null]]},"references-count":0,"URL":"https:\/\/doi.org\/10.7554\/elife.45590.017","relation":{"is-component-of":[{"id-type":"doi","id":"10.7554\/eLife.45590","asserted-by":"object"}]}},{"indexed":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T09:41:21Z","timestamp":1729676481064,"version":"3.28.0"},"reference-count":7,"publisher":"IEEE","content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2006,10]]},"DOI":"10.1109\/icr.2006.343184","type":"proceedings-article","created":{"date-parts":[[2007,4,24]],"date-time":"2007-04-24T18:10:34Z","timestamp":1177438234000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["A Full-Rate Tracking Algorithm of Maneuvering Target Based on Multi-Rate CS and CV Models"],"prefix":"10.1109","author":[{"given":"Ting","family":"Cheng","sequence":"first","affiliation":[]},{"given":"Zishu","family":"He","sequence":"additional","affiliation":[]},{"given":"Huiyong","family":"Li","sequence":"additional","affiliation":[]},{"given":"Benyong","family":"Liu","sequence":"additional","affiliation":[]}],"member":"263","reference":[{"key":"3","doi-asserted-by":"publisher","DOI":"10.1109\/ACC.1994.751909"},{"key":"2","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1109\/7.272274","article-title":"Multiresolutional multiple-model target tracking","volume":"30","author":"hong","year":"1994","journal-title":"IEEE Trans Aerospace Electron Syst"},{"key":"1","doi-asserted-by":"publisher","DOI":"10.1109\/9.286269"},{"key":"7","first-page":"92","author":"wanhai","year":"2004","journal-title":"Multi-sensor data confusion and its application"},{"key":"6","first-page":"134","author":"hongren","year":"1991","journal-title":"Tracking of maneuvering targets"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1109\/9.1299"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/0167-6911(93)90093-L"}],"event":{"name":"2006 CIE International Conference on Radar","start":{"date-parts":[[2006,10,16]]},"location":"Shanghai, China","end":{"date-parts":[[2006,10,19]]}},"container-title":["2006 CIE International Conference on Radar"],"link":[{"URL":"http:\/\/xplorestaging.ieee.org\/ielx5\/4148130\/4118064\/04148290.pdf?arnumber=4148290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,17]],"date-time":"2017-06-17T16:40:27Z","timestamp":1497717627000},"score":16.771904,"resource":{"primary":{"URL":"http:\/\/ieeexplore.ieee.org\/document\/4148290\/"}},"issued":{"date-parts":[[2006,10]]},"references-count":7,"URL":"https:\/\/doi.org\/10.1109\/icr.2006.343184","published":{"date-parts":[[2006,10]]}},{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T13:10:26Z","timestamp":1770469826722,"version":"3.49.0"},"reference-count":0,"publisher":"Current Science Association","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CS"],"DOI":"10.18520\/cs\/v128\/i4\/368-372","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T07:26:49Z","timestamp":1741678009000},"page":"368-372","source":"Crossref","is-referenced-by-count":1,"title":["Climatic influences on flowering dynamics, reproductive development and fruit set in litchi cv. Dehradun"],"prefix":"10.18520","volume":"128","author":[{"given":"Shiv Kumar","family":"Shivandu","sequence":"first","affiliation":[]},{"given":"Gaurav","family":"Kumar","sequence":"additional","affiliation":[]},{"given":"Ishani","family":"Sharma","sequence":"additional","affiliation":[]},{"given":"Jayesh","family":"Garg","sequence":"additional","affiliation":[]}],"member":"7781","published-online":{"date-parts":[[2025,2,25]]},"container-title":["Current Science"],"link":[{"URL":"https:\/\/www.currentscience.ac.in\/Volumes\/128\/04\/0368.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T11:06:53Z","timestamp":1758193613000},"score":16.688316,"resource":{"primary":{"URL":"https:\/\/www.currentscience.ac.in\/Volumes\/128\/04\/0368.pdf"}},"issued":{"date-parts":[[2025,2,25]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,2,25]]}},"URL":"https:\/\/doi.org\/10.18520\/cs\/v128\/i4\/368-372","ISSN":["0011-3891"],"issn-type":[{"value":"0011-3891","type":"print"}],"published":{"date-parts":[[2025,2,25]]}},{"indexed":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T05:38:17Z","timestamp":1725428297613},"reference-count":0,"publisher":"Academy & Industry Research Collaboration Center (AIRCC)","content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2012,1,4]]},"DOI":"10.5121\/csit.2012.2127","type":"proceedings-article","created":{"date-parts":[[2012,3,5]],"date-time":"2012-03-05T18:00:09Z","timestamp":1330970409000},"page":"291-302","source":"Crossref","is-referenced-by-count":0,"title":["State Space Point Distribution Parameter for Support Vector Machine Based CV Unit Classification"],"prefix":"10.5121","volume":"4","author":[{"given":"Narayanan","family":"N K","sequence":"first","affiliation":[]}],"member":"3062","event":{"name":"The First International Conference on Information Technology Convergence and Services","acronym":"ITCS - 2012"},"container-title":["Computer Science &amp; Information Technology(CS&amp;IT)","Computer Science Conference Proceedings"],"deposited":{"date-parts":[[2012,3,5]],"date-time":"2012-03-05T18:00:41Z","timestamp":1330970441000},"score":16.39389,"resource":{"primary":{"URL":"http:\/\/www.airccj.org\/CSCP\/vol2\/csit2127.pdf"}},"issued":{"date-parts":[[2012,1,4]]},"references-count":0,"URL":"https:\/\/doi.org\/10.5121\/csit.2012.2127","ISSN":["2231-5403"],"issn-type":[{"type":"print","value":"2231-5403"}],"published":{"date-parts":[[2012,1,4]]}},{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T02:29:04Z","timestamp":1771381744131,"version":"3.50.1"},"reference-count":24,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Otago Polytechnic and the Manhattan Institute"}],"content-domain":{"domain":[],"crossmark-restriction":false},"abstract":"<jats:p>\n                    This study examines the choices made by Large Language Models (LLMs) when selecting professional candidates for a job based on their r\u00e9sum\u00e9s or curricula vitae (CVs). In an experiment involving 22 leading LLMs, each model was systematically given a job description along with a pair of profession-matched CVs\u2014one bearing a male first name, the other a female first name\u2014and asked to select the more suitable candidate for the job. Each CV pair was presented twice, with names swapped to ensure that any observed preferences in candidate selection stemmed from gendered names cues. Despite equalized professional qualifications between genders, all LLMs consistently favored female-named candidates across 70 different professions. Adding an explicit gender field (male\/female) to the CVs further increased the preference for female applicants. When gendered names were replaced with gender-neutral identifiers (\n                    <jats:italic>i.e<\/jats:italic>\n                    ., Candidate A\/B), several models displayed a slight preference for selecting \u201cCandidate A\u201d. Counterbalancing gender assignment between these gender-neutral identifiers resulted in gender parity in candidate selection. When asked to rate CVs in isolation rather than compare pairs, LLMs assigned slightly higher average scores to female CVs overall, but the effect size was negligible. Including preferred pronouns (he\/him or she\/her) next to a candidate\u2019s name slightly increased the odds of the candidate being selected. Finally, most models exhibited a substantial positional bias to select the candidate listed first in the prompt. These findings underscore the need for caution when deploying LLMs in high-stakes autonomous decision-making contexts and raise doubts about whether LLMs consistently apply principled reasoning.\n                  <\/jats:p>","DOI":"10.7717\/peerj-cs.3628","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T08:54:51Z","timestamp":1771318491000},"page":"e3628","source":"Crossref","is-referenced-by-count":1,"title":["Gender and positional biases in LLM-based hiring decisions: evidence from comparative CV\/r\u00e9sum\u00e9 evaluations"],"prefix":"10.7717","volume":"12","author":[{"given":"David","family":"Rozado","sequence":"first","affiliation":[]}],"member":"4443","published-online":{"date-parts":[[2026,2,17]]},"reference":[{"issue":"3","key":"10.7717\/peerj-cs.3628\/ref-1","doi-asserted-by":"publisher","first-page":"pgaf089","DOI":"10.1093\/pnasnexus\/pgaf089","article-title":"Measuring gender and racial biases in large language models: intersectional evidence from automated resume evaluation","volume":"4","author":"An","year":"2025","journal-title":"PNAS Nexus"},{"issue":"3","key":"10.7717\/peerj-cs.3628\/ref-2","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1093\/esr\/jcab043","article-title":"Gender discrimination in hiring: evidence from a cross-national harmonized field experiment","volume":"38","author":"Birkelund","year":"2022","journal-title":"European Sociological Review"},{"key":"10.7717\/peerj-cs.3628\/ref-3","article-title":"Employed persons by detailed occupation, sex, race, and Hispanic or Latino ethnicity","author":"Bureau of Labor Statistics","year":"2024"},{"issue":"6334","key":"10.7717\/peerj-cs.3628\/ref-4","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1126\/science.aal4230","article-title":"Semantics derived automatically from language corpora contain human-like biases","volume":"356","author":"Caliskan","year":"2017","journal-title":"Science"},{"key":"10.7717\/peerj-cs.3628\/ref-5","article-title":"CV Screening: AI inside your ATS","author":"CiiVSOFT","year":"2025"},{"key":"10.7717\/peerj-cs.3628\/ref-6","first-page":"797","article-title":"Algorithmic decision making and the cost of fairness","author":"Corbett-Davies","year":"2017"},{"issue":"16","key":"10.7717\/peerj-cs.3628\/ref-7","doi-asserted-by":"publisher","first-page":"E3635-44","DOI":"10.1073\/pnas.1720347115","article-title":"Word embeddings quantify 100 years of gender and ethnic stereotypes","volume":"115","author":"Garg","year":"2018","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.7717\/peerj-cs.3628\/ref-8","doi-asserted-by":"crossref","first-page":"5777","DOI":"10.18653\/v1\/2024.findings-emnlp.331","article-title":"Gender bias in decision-making with large language models: a study of relationship conflicts","volume-title":"Findings of the Association for Computational Linguistics: EMNLP, 2024","author":"Levy","year":"2024"},{"issue":"1","key":"10.7717\/peerj-cs.3628\/ref-9","doi-asserted-by":"publisher","first-page":"100054","DOI":"10.1016\/j.chbah.2024.100054","article-title":"Computer says \u2018no\u2019: exploring systemic bias in ChatGPT using an audit approach","volume":"2","author":"Lippens","year":"2024","journal-title":"Computers in Human Behavior: Artificial Humans"},{"issue":"6178","key":"10.7717\/peerj-cs.3628\/ref-10","doi-asserted-by":"publisher","first-page":"104315","DOI":"10.1016\/j.euroecorev.2022.104315","article-title":"The state of hiring discrimination: a meta-analysis of (almost) all recent correspondence experiments","volume":"151","author":"Lippens","year":"2023","journal-title":"European Economic Review"},{"key":"10.7717\/peerj-cs.3628\/ref-11","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.2307.03172","article-title":"Lost in the middle: how language models use long contexts","author":"Liu","year":"2023"},{"issue":"5","key":"10.7717\/peerj-cs.3628\/ref-12","doi-asserted-by":"publisher","first-page":"358","DOI":"10.3390\/info16050358","article-title":"Quantifying gender bias in large language models using information-theoretic and statistical analysis","volume":"16","author":"Mirza","year":"2025","journal-title":"Information"},{"key":"10.7717\/peerj-cs.3628\/ref-13","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.2406.16275","article-title":"Investigating the influence of prompt-specific shortcuts in AI generated text detection","author":"Park","year":"2024"},{"key":"10.7717\/peerj-cs.3628\/ref-14","doi-asserted-by":"publisher","first-page":"26","DOI":"10.15195\/v12.a2","article-title":"Getting a foot in the door: a meta-analysis of U.S. audit studies of gender bias in hiring","volume":"12","author":"Park","year":"2025","journal-title":"Sociological Science"},{"key":"10.7717\/peerj-cs.3628\/ref-15","article-title":"First come, first hired? ChatGPT\u2019s bias for the first resume it sees and the cost for candidates to overcome bias in AI hiring tools","author":"Puutio","year":"2025"},{"issue":"41","key":"10.7717\/peerj-cs.3628\/ref-16","doi-asserted-by":"publisher","first-page":"10870","DOI":"10.1073\/pnas.1706255114","article-title":"Meta-analysis of field experiments shows no change in racial discrimination in hiring over time","volume":"114","author":"Quillian","year":"2017","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"4","key":"10.7717\/peerj-cs.3628\/ref-17","doi-asserted-by":"publisher","first-page":"e0231189","DOI":"10.1371\/journal.pone.0231189","article-title":"Wide range screening of algorithmic bias in word embedding models using large sentiment lexicons reveals underreported bias types","volume":"15","author":"Rozado","year":"2020","journal-title":"PLOS ONE"},{"key":"10.7717\/peerj-cs.3628\/ref-18","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.2505.17049","article-title":"Gender and positional biases in LLM-based hiring decisions: evidence from comparative CV\/R\u00e9sum\u00e9 evaluations","author":"Rozado","year":"2025"},{"key":"10.7717\/peerj-cs.3628\/ref-19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1145\/3617694.3623257","article-title":"The unequal opportunities of large language models: examining demographic biases in job recommendations by ChatGPT and LLaMA","author":"Salinas","year":"2023"},{"key":"10.7717\/peerj-cs.3628\/ref-20","article-title":"Ubidy: validating skills beyond the resume","author":"Shellshear","year":"2024"},{"key":"10.7717\/peerj-cs.3628\/ref-21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1109\/SCES61914.2024.10652548","article-title":"ProspectCV: LLM-based advanced CV-JD evaluation platform","author":"Vagale","year":"2024"},{"key":"10.7717\/peerj-cs.3628\/ref-22","first-page":"1578","article-title":"Race, and intersectional bias in resume screening via language model retrieval","author":"Wilson","year":"2025"},{"key":"10.7717\/peerj-cs.3628\/ref-23","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.2506.14092","article-title":"Fragile preferences: a deep dive into order effects in large language models","author":"Yin","year":"2025"},{"key":"10.7717\/peerj-cs.3628\/ref-24","article-title":"Boosting recruitment efficiency with multimodal LLMs and GenAI","author":"Zoolatech","year":"2025"}],"container-title":["PeerJ Computer Science"],"language":"en","link":[{"URL":"https:\/\/peerj.com\/articles\/cs-3628.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/articles\/cs-3628.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/articles\/cs-3628.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/articles\/cs-3628.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T08:54:53Z","timestamp":1771318493000},"score":16.270157,"resource":{"primary":{"URL":"https:\/\/peerj.com\/articles\/cs-3628"}},"issued":{"date-parts":[[2026,2,17]]},"references-count":24,"alternative-id":["10.7717\/peerj-cs.3628"],"URL":"https:\/\/doi.org\/10.7717\/peerj-cs.3628","archive":["CLOCKSS","LOCKSS","Portico"],"ISSN":["2376-5992"],"issn-type":[{"value":"2376-5992","type":"electronic"}],"published":{"date-parts":[[2026,2,17]]},"article-number":"e3628"},{"indexed":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T14:15:07Z","timestamp":1656512107851},"reference-count":0,"publisher":"American Association for Cancer Research (AACR)","issue":"24_Supplement","content-domain":{"domain":["aacrjournals.org"],"crossmark-restriction":true},"published-print":{"date-parts":[[2011,12,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The circadian clock is a molecular mechanism that synchronizes environment variations with physiological changes. Disruption of the circadian clock has been linked to increased risk in diseases and a number of disorders (e.g. jet lag, insomnia, coronary heart disease and cancer). Period 2 (PER2), a circadian protein, is at the center of the clock's function. The complete loss of per2 has been shown to be common in several types of cancer including breast and ovarian. Epidemiological studies established a correlation between circadian disruption and the development of estrogen dependent tumors. The expression of estrogen receptor alpha (ERa) mRNA oscillates in a 24-hour period and, unlike PER2, ERa peaks during the light phase of the day. Because up regulation of ER relates to tumor development, defining the mechanisms of ERa expression will contribute to our comprehension of cellular proliferation and regulation of normal developmental processes. The overall goal of this project is to investigate the molecular basis for circadian control of estrogen receptor alpha (ERa) transcription.<\/jats:p>\n               <jats:p>Transcriptional activation of ERa was measured using a reporter system in Chinese Hamster Ovary and MCF-7 cell lines. Data show that PER2 influence ERa transcription through a non-canonical mechanism independent of its circadian counterparts. Promoter analysis using the Alibaba 2.0 suite revealed the presence of various putative novel partners. Among them, OCT-1 was found to directly interact with Per2, in vitro, and with corresponding response element within the ERa promoter. The predicted binding site of OCT-1 is 267 bps upstream of the promoter. Pull-down assays were used to map direct interaction of various PER2 recombinant proteins and the DNA-binding domain of OCT-1. Radiolabeled OCT-1 was found to bind to the C-terminal end of PER2. Electrophoretic mobility shift assays were used to determine direct binding of OCT-1 to the promoter. ChIP assay confirmed the recruitment of PER2 to the estrogen promoter by OCT-1. Fluorescence anisotropy and surface plasmon resonance were employed to establish the binding affinity of OCT-1 to the ERa promoter and PER2. OCT-1 was found to have a high affinity for the ERa promoter (\u223c10 nM). Furthermore, OCT-1 recruits PER2 to the estrogen promoter. Preliminary data suggests that the transcription factor PER2 might play a role in the regulation of the estrogen promoter.<\/jats:p>\n               <jats:p>Citation Information: Cancer Res 2011;71(24 Suppl):Abstract nr P5-03-04.<\/jats:p>","DOI":"10.1158\/0008-5472.sabcs11-p5-03-04","type":"journal-article","created":{"date-parts":[[2012,6,27]],"date-time":"2012-06-27T14:33:36Z","timestamp":1340807616000},"page":"P5-03-04-P5-03-04","update-policy":"http:\/\/dx.doi.org\/10.1158\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["P5-03-04: Circadian Modulation of Estrogen Receptor alpha Promoter Activity."],"prefix":"10.1158","volume":"71","author":[{"given":"LM","family":"Villa","sequence":"first","affiliation":[{"name":"1Virginia Polytechnic Institute and State University, Blacksburg, VA"}]},{"given":"CS","family":"Santos","sequence":"additional","affiliation":[{"name":"1Virginia Polytechnic Institute and State University, Blacksburg, VA"}]},{"given":"S","family":"Cousins","sequence":"additional","affiliation":[{"name":"1Virginia Polytechnic Institute and State University, Blacksburg, VA"}]},{"given":"CV","family":"Finkielstein","sequence":"additional","affiliation":[{"name":"1Virginia Polytechnic Institute and State University, Blacksburg, VA"}]}],"member":"1086","container-title":["Cancer 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In addition to improving the crop, using nanomaterials in agriculture can reduce the harmful effects of environmental stresses, particularly salinity. A factorial experiment was conducted in the form of a completely randomized design with two factors including salt stress at three levels (0, 50, and 100\u00a0mM NaCl) and chitosan-salicylic acid nanocomposite at three levels (0, 0.1, and 0.5\u00a0mM). The results showed reductions in chlorophylls (a, b, and total), carotenoids, and nutrient elements (excluding sodium) while proline, hydrogen peroxide, malondialdehyde, total soluble protein, soluble carbohydrate, total antioxidant, and antioxidant enzymes activity increased with treatment chitosan-salicylic acid nanocomposite (CS-SA NCs) under different level NaCl. Salinity stress reduced Fm', Fm, and Fv\/Fm by damage to photosynthetic systems, but treatment with CS-SA NCs improved these indices during salinity stress. In stress-free conditions, applying the CS-SA NCs improved the grapes' physiological, biochemical, and nutrient elemental balance traits. CS-SA NCs at 0.5\u00a0mM had a better effect on the studied traits of grapes under salinity stress. The CS-SA nanoparticle is a biostimulant that can be effectively used to improve the grape plant yield under salinity stress.<\/jats:p>","DOI":"10.1038\/s41598-023-27618-z","type":"journal-article","created":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T11:05:23Z","timestamp":1673953523000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":76,"title":["Protective effects of chitosan based salicylic acid nanocomposite (CS-SA NCs) in grape (Vitis vinifera cv. \u2018Sultana\u2019) under salinity stress"],"prefix":"10.1038","volume":"13","author":[{"given":"Mohammad Ali","family":"Aazami","sequence":"first","affiliation":[]},{"given":"Maryam","family":"Maleki","sequence":"additional","affiliation":[]},{"given":"Farzad","family":"Rasouli","sequence":"additional","affiliation":[]},{"given":"Gholamreza","family":"Gohari","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2023,1,17]]},"reference":[{"key":"27618_CR1","volume-title":"Plant Phenolics in Sustainable Agriculture","author":"TS Hoque","year":"2020","unstructured":"Hoque, T. 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This study aimed to determine the effect of partially purified fractions of extracellular proteins secreted by\n                  <jats:italic>C. septicum<\/jats:italic>\n                  on the death of mouse peritoneal macrophages. Elicited mouse peritoneal macrophages were incubated with partially purified fractions of proteins secreted by\n                  <jats:italic>C. septicum<\/jats:italic>\n                  into the culture medium. After incubation, we found that the protein fraction with a molecular weight \u2265 100 kDa caused significant cell death in macrophages, changed cell morphology, increased markers of apoptosis and autophagy, and increased the expression (protein and mRNA) of IL-10 and TNF\u03b1 Our data suggest that the proteins secreted by\n                  <jats:italic>C. septicum<\/jats:italic>\n                  (MW, \u2265 kDa) induce cell death in macrophages by promoting autophagy- triggered apoptosis. This study may contribute to our understanding of the molecular mechanism of immune evasion by\n                  <jats:italic>C. septicum<\/jats:italic>\n                  at the infection site.\n                <\/jats:p>","DOI":"10.1101\/2024.06.18.599648","type":"posted-content","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T23:55:13Z","timestamp":1718841313000},"source":"Crossref","is-referenced-by-count":0,"title":["Exotoxins secreted by\n                  <i>Clostridium septicum<\/i>\n                  induce macrophage death:\n                  <i>implications for bacterial immune evasion mechanisms at infection sites<\/i>"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4509-0161","authenticated-orcid":false,"given":"RM","family":"Ortiz 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Plant Sci."],"abstract":"<jats:p>The cotton chromosome substitution line, CS-B15sh, exhibits 41% lower injury from 2,4-D when applied at the field recommended rate of 1.12 kg ae ha<jats:sup>\u22121<\/jats:sup> (1\u00d7) than does Texas Marker-1 (TM-1). CS-B15sh was developed in the genetic background of <jats:italic>Gossypium hirsutum<\/jats:italic> L. cv TM-1 and has chromosome introgression on the short arm of chromosome 15 from <jats:italic>Gossypium barbadense<\/jats:italic> L. cv. Pima 379. In a previous experiment, we observed reduced translocation of [<jats:sup>14<\/jats:sup>C]2,4-D outside the treated leaf tissue in CS-B15sh, which contrasted with an increased translocation of the herbicide in the tissues above and below the treated leaf in TM-1. Our results indicate a potential 2,4-D tolerance mechanism in CS-B15sh involving altered movement of 2,4-D. Here, we used RNA sequencing (RNA-seq) to determine the differential expression of genes between 2,4-D-challenged and control plants of the tolerant (CS-B15sh) and susceptible lines (TM-1 and Pima 379). Several components of the 2,4-D\/auxin-response pathway\u2014including ubiquitin E3 ligase, PB1|AUX\/IAA, ARF transcription factors, and F-box proteins of the SCF<jats:sup>TIR1\/AFB<\/jats:sup> complex\u2014were upregulated with at least threefold higher expression in TM-1 compared with CS-B15sh, while both Pima 379 and TM-1 showed the same fold change expression for PB1|AUX\/IAA mRNA. Some genes associated with herbicide metabolism, including flavin monooxygenase (Gohir.A01G174100) and FAD-linked oxidase (Gohir.D06G002600), exhibited at least a twofold increase in CS-B15sh than in TM-1 (the gene was not expressed in Pima 379), suggesting a potential relationship between the gene\u2019s expression and 2,4-D tolerance. It is interesting to note that glutathione S-transferase was differentially expressed in both CS-B15sh and Pima 379 but not in TM-1, while cytochrome P450 and other genes involved in the oxidation\u2013reduction process were significantly expressed only in CS-B15sh in response to 2,4-D. Gene set enrichment analysis on the union DEGs of the three cotton genotypes revealed the depletion of transcripts involved in photosynthesis and enrichment of transcripts involved in ABA response and signaling.<\/jats:p>","DOI":"10.3389\/fpls.2022.910369","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T08:27:22Z","timestamp":1661156842000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Transcriptome analysis of the 2,4-dichlorophenoxyacetic acid (2,4-D)-tolerant cotton chromosome substitution line CS-B15sh and its susceptible parental lines G. hirsutum L. cv. 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For this purpose, abaca fiber was added according to the dry mass of the soil, in lengths (5, 10, and 15 mm) and concentrations (0.5, 1.0, and 1.5%) subjected to a curing process with sodium hydroxide (NaOH). The virgin and fiber-added soil samples were reconstituted as slurry, and one-dimensional consolidation tests were performed in accordance with ASTM D2435. The results showed a reduction in void ratio (compared to the soil without fiber) and an increase in the coefficient of consolidation (Cv) as a function of fiber concentration and length, with values corresponding to 1.5% and 15 mm increasing from 75.16 to 144.51 cm2\/s. Although no significant values were obtained for the compression and expansion coefficients, it was assumed that the soil maintained its compressibility. The statistical analysis employed hierarchical linear models to assess the significance of the effects of incorporating fibers of varying lengths and percentages on the coefficients, comparing them with the control samples. Concurrently, mixed linear models were utilized to evaluate the influence of the methods for obtaining the Cv, revealing that Taylor\u2019s method yielded more conservative values, whereas the Casagrande method produced higher values.<\/jats:p>","DOI":"10.3390\/fib12100089","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T11:28:51Z","timestamp":1729078131000},"page":"89","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Influence of Abaca Fiber Treated with Sodium Hydroxide on the Deformation Coefficients Cc, Cs, and Cv of Organic Soils"],"prefix":"10.3390","volume":"12","author":[{"given":"Carlos","family":"Contreras","sequence":"first","affiliation":[{"name":"Facultad de Ciencias, Ingenier\u00eda y Construcci\u00f3n, Ingenier\u00eda Civil, Universidad UTE, Quito 170527, Ecuador"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3981-2201","authenticated-orcid":false,"given":"Jorge","family":"Albuja-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Laboratory of Materials Resistance, Soil Mechanics, Pavements and Geotechnics, Faculty of Engineering, Pontificia Universidad Cat\u00f3lica del Ecuador (PUCE), Quito 170143, Ecuador"},{"name":"International Faculty of Innovation PUCE-Icam, Pontificia Universidad Cat\u00f3lica del Ecuador (PUCE), Quito 170143, Ecuador"}]},{"given":"Oswaldo","family":"Proa\u00f1o","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias, Ingenier\u00eda y Construcci\u00f3n, Ingenier\u00eda Civil, Universidad UTE, Quito 170527, Ecuador"},{"name":"Grupo de Investigaci\u00f3n de Energ\u00eda, Minas y Agua (GIEMA), Facultad de Ciencias, Ingenier\u00eda y Construcci\u00f3n, Universidad UTE, Quito 170527, Ecuador"}]},{"given":"Carlos","family":"\u00c1vila","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias, Ingenier\u00eda y Construcci\u00f3n, Ingenier\u00eda Civil, Universidad UTE, Quito 170527, Ecuador"},{"name":"Grupo de Investigaci\u00f3n de Energ\u00eda, Minas y Agua (GIEMA), Facultad de Ciencias, Ingenier\u00eda y Construcci\u00f3n, Universidad UTE, Quito 170527, Ecuador"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5707-8199","authenticated-orcid":false,"given":"Andreina","family":"Dami\u00e1n-Chal\u00e1n","sequence":"additional","affiliation":[{"name":"Laboratory of Materials Resistance, Soil Mechanics, Pavements and Geotechnics, Faculty of Engineering, Pontificia Universidad Cat\u00f3lica del Ecuador (PUCE), Quito 170143, Ecuador"}]},{"given":"Mateo","family":"Pe\u00f1aherrera-Aguirre","sequence":"additional","affiliation":[{"name":"School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ 85721, USA"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,15]]},"reference":[{"key":"ref_1","first-page":"27","article-title":"Suelos Reforzados con Fibras: Estado del Arte y Aplicaciones","volume":"1","author":"Vettorelo","year":"2014","journal-title":"Rev. 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En este trabajo, se describe una mortandad debido a esta afecci\u00f3n, en vacas de cr\u00eda en el Noroeste argentino. La pastura donde los animales permanec\u00edan correspond\u00eda a Megathyrsus maximus cv. Gatton, vulgarmente m\u00e1s conocido como \u201cGatton Panic\u201d. Los signos cl\u00ednicos fueron anorexia, p\u00e9rdida de estado hasta que los animales cayeron sin posibilidades de incorporarse y posteriormente mor\u00edan. El diagn\u00f3stico se confirm\u00f3 por los antecedentes cl\u00ednicos, patol\u00f3gicos y epidemiol\u00f3gicos sumados al an\u00e1lisis de la pastura. El cuadro de impactaci\u00f3n ruminal y abomasal est\u00e1 bien descripto en la bibliograf\u00eda, pero ha sido poco reportado en Argentina.<\/jats:p>","DOI":"10.14409\/favecv.v18i1.8234","type":"journal-article","created":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T17:55:04Z","timestamp":1558461304000},"page":"12-16","source":"Crossref","is-referenced-by-count":0,"title":["Impactaci\u00f3n ruminal y abomasal en vacas de cr\u00eda asociada al consumo de una pastura diferida de Megathyrsus maximus cv. 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