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Research"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Dementia and cardiovascular disease (CVD) are frequently comorbid. The presence of dementia may have an effect on how CVD is treated.<jats:italic>Objective<\/jats:italic>. To examine the effect of dementia on the use of four medications recommended for secondary prevention of ischemic heart disease (IHD): angiotensin-converting enzyme inhibitors, beta-blockers, lipid-lowering medications, and antiplatelet medications.<jats:italic>Design<\/jats:italic>. Retrospective analysis of data from the Cardiovascular Health Study: Cognition Study.<jats:italic>Setting and Subjects<\/jats:italic>. 1,087 older adults in four US states who had or developed IHD between 1989 and 1998.<jats:italic>Methods<\/jats:italic>. Generalized estimating equations to explore the association between dementia and the use of guideline-recommended medications for the secondary prevention of IHD.<jats:italic>Results<\/jats:italic>. The length of follow-up for the cohort was 8.7 years and 265 (24%) had or developed dementia during the study. Use of medications for the secondary prevention of IHD for patients with and without dementia increased during the study period. In models, subjects with dementia were not less likely to use any one particular class of medication but were less likely to use two or more classes of medications as a group (OR, 0.60; 95% CI, 0.36\u20130.99).<jats:italic>Conclusions<\/jats:italic>. Subjects with dementia used fewer guideline-recommended medications for the secondary prevention of IHD than those without dementia.<\/jats:p>","DOI":"10.1155\/2014\/897671","type":"journal-article","created":{"date-parts":[[2014,2,26]],"date-time":"2014-02-26T01:14:18Z","timestamp":1393377258000},"page":"1-8","source":"Crossref","is-referenced-by-count":7,"title":["Effect of Dementia on the Use of Drugs for Secondary Prevention of Ischemic Heart Disease"],"prefix":"10.1155","volume":"2014","author":[{"given":"Nicole R.","family":"Fowler","sequence":"first","affiliation":[{"name":"Division of General Internal Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA"}]},{"given":"Amber E.","family":"Barnato","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA"},{"name":"Department of Health Policy and 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Recent studies report that acute stroke patients who present to the hospital on weekends have higher rates of 28-day mortality than similar patients who arrive during the week. However, how this association is related to clinical presentation and stroke type has not been systematically investigated.<jats:italic>Methods and Results<\/jats:italic>. We examined the association between day of arrival and 28-day mortality in 929 validated stroke events in the ARIC cohort from 1987\u20132004. Weekend arrival was defined as any arrival time from midnight Friday until midnight Sunday. Mortality was defined as all-cause fatal events from the day of arrival through the 28th day of followup. The presence or absence of thirteen stroke signs and symptoms were obtained through medical record review for each event. Binomial logistic regression was used to estimate odds ratios and 95% confidence intervals (OR; 95% CI) for the association between weekend arrival and 28-day mortality for all stroke events and for stroke subtypes. The overall risk of 28-day mortality was 9.6% for weekday strokes and 10.1% for weekend strokes. In models controlling for patient demographics, clinical risk factors, and event year, weekend arrival was not associated with 28-day mortality (0.87; 0.51, 1.50). When stratified by stroke type, weekend arrival was not associated with increased odds of mortality for ischemic (1.17, 0.62, 2.23) or hemorrhagic (0.37; 0.11, 1.26) stroke patients.<jats:italic>Conclusions<\/jats:italic>. Presence or absence of thirteen signs and symptoms was similar for weekday patients and weekend patients when stratified by stroke type. 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The traditional definitions of overweight and obesity are not age specific, even though the relationship of weight to mortality is different for older adults. Effects of adiposity on aspects of health beside mortality have not been well investigated.<jats:italic>Methods<\/jats:italic>. We calculated the number of years of healthy life (YHL) in the 10 years after baseline, for 5,747 older adults. YHL was defined in 16 different ways. We compared Normal and Overweight persons, classified either by body mass index (BMI) or by waist circumference (WC).<jats:italic>Findings<\/jats:italic>. YHL for Normal and Overweight persons differed significantly in 25% of the comparisons, of which half favored the Overweight. Measures of physical health favored Normal weight, while measures of mental health and quality of life favored Overweight. Overweight was less favorable when defined by WC than by BMI. Obese persons usually had worse outcomes.<jats:italic>Discussion<\/jats:italic>. Overweight older adults averaged as many years of life and years of healthy life as those of Normal weight. There may be no outcome based reason to distinguish Normal from Overweight for older adults.<jats:italic>Conclusion<\/jats:italic>. The \u201cOverweight paradox\u201d appears to hold for nonmortality outcomes. New adiposity standards are needed for older adults, possibly different by race and sex.<\/jats:p>","DOI":"10.1155\/2012\/894894","type":"journal-article","created":{"date-parts":[[2012,6,21]],"date-time":"2012-06-21T08:07:49Z","timestamp":1340266069000},"page":"1-13","source":"Crossref","is-referenced-by-count":7,"title":["Comparing Years of Healthy Life, Measured in 16 Ways, for Normal Weight and Overweight Older Adults"],"prefix":"10.1155","volume":"2012","author":[{"given":"Paula","family":"Diehr","sequence":"first","affiliation":[{"name":"Department of Biostatistics, University of Washington, Seattle, WA 98195, USA"},{"name":"Department of Health Services, University of Washington, Seattle, WA 98195, USA"}]},{"given":"Stephen","family":"Thielke","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Washington, Seattle, WA 98195, USA"},{"name":"Geriatric Research, Education, and Clinical Center, Puget Sound VA Medical Center, Seattle, WA 98195, 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acid binding protein 4 (FABP4) may increase risk of diabetes and exert negative cardiac inotropy, it is unknown whether plasma concentrations of FABP4 are associated with incidence of sudden cardiac death (SCD). We prospectively analyzed data on 4,560 participants of the Cardiovascular Health Study. FABP4 was measured at baseline using ELISA, and SCD events were adjudicated through review of medical records. We used Cox proportional hazards to estimate effect measures. During a median followup of 11.8 years, 146 SCD cases occurred. In a multivariable model adjusting for demographic, lifestyle, and metabolic factors, relative risk of SCD associated with each higher standard deviation (SD) of plasma FABP4 was 1.15 (95% CI: 0.95\u20131.38),<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.15<\/mml:mn><\/mml:math>. In a secondary analysis stratified by prevalent diabetes status, FABP4 was associated with higher risk of SCD in nondiabetic participants, (RR per SD higher FABP4: 1.33 (95% CI: 1.07\u20131.65),<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.009<\/mml:mn><\/mml:math>) but not in diabetic participants (RR per SD higher FABP4: 0.88 (95% CI: 0.62\u20131.27),<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.50<\/mml:mn><\/mml:math>),<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mi>P<\/mml:mi><\/mml:mrow><\/mml:math>for diabetes-FABP4 interaction 0.049. In summary, a single measure of plasma FABP4 obtained later in life was not associated with the risk of SCD in older adults overall. Confirmation of our post-hoc results in nondiabetic people in other studies is warranted.<\/jats:p>","DOI":"10.1155\/2013\/181054","type":"journal-article","created":{"date-parts":[[2013,12,28]],"date-time":"2013-12-28T21:00:32Z","timestamp":1388264432000},"page":"1-7","source":"Crossref","is-referenced-by-count":2,"title":["Plasma Fatty Acid Binding Protein 4 and Risk of Sudden Cardiac Death in Older Adults"],"prefix":"10.1155","volume":"2013","author":[{"given":"Luc","family":"Djouss\u00e9","sequence":"first","affiliation":[{"name":"Division of Aging, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, 1620 Tremont Street, 3rd Floor, Boston, MA 02120, USA"},{"name":"Boston Veterans Affairs Healthcare System, Boston, MA 02130, USA"}]},{"given":"Marlena","family":"Maziarz","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Washington, Seattle, WA 98195, USA"}]},{"given":"Mary L.","family":"Biggs","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Washington, Seattle, WA 98195, USA"}]},{"given":"Joachim H.","family":"Ix","sequence":"additional","affiliation":[{"name":"Nephrology Section, Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA"},{"name":"Divisions of Nephrology and Preventive Medicine, University of California San Diego, San Diego, CA 92093, USA"}]},{"given":"Susan J.","family":"Zieman","sequence":"additional","affiliation":[{"name":"National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA"}]},{"given":"Jorge R.","family":"Kizer","sequence":"additional","affiliation":[{"name":"Cardiology Division, Albert Einstein College of Medicine, New York, NY 10461, USA"}]},{"given":"Rozenn N.","family":"Lemaitre","sequence":"additional","affiliation":[{"name":"Cardiovascular Health Research Unit, Departments of Medicine, University of Washington, Seattle, WA 98195, USA"}]},{"given":"Dariush","family":"Mozaffarian","sequence":"additional","affiliation":[{"name":"Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA 02120, USA"}]},{"given":"Russell P.","family":"Tracy","sequence":"additional","affiliation":[{"name":"Department of Pathology and Biochemistry, University of Vermont College of Medicine, Burlington, VT 05401, USA"}]},{"given":"Kenneth J.","family":"Mukamal","sequence":"additional","affiliation":[{"name":"Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02120, USA"}]},{"given":"David S.","family":"Siscovick","sequence":"additional","affiliation":[{"name":"Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, WA 98195, USA"}]},{"given":"Nona","family":"Sotoodehnia","sequence":"additional","affiliation":[{"name":"Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, WA 98195, USA"}]}],"member":"311","reference":[{"issue":"18","key":"1","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1161\/hc4301.098254","volume":"104","year":"2001","journal-title":"Circulation"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.06.029"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.807289"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020245"},{"key":"5","doi-asserted-by":"crossref","first-page":"33","DOI":"10.7326\/0003-4819-55-1-33","volume":"55","year":"1961","journal-title":"Annals of Internal 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Pepper Older American Independence Centers","award":["HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"],"award-info":[{"award-number":["HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"]}]},{"name":"NCATS","award":["HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"],"award-info":[{"award-number":["HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"]}]},{"name":"MESA study","award":["HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"],"award-info":[{"award-number":["HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["GUCDD"],"abstract":"<jats:p>(1) The Multi-Ethnic Study of Atherosclerosis (MESA) is a multi-center longitudinal cohort study designed to investigate the risk factors associated with the incidence of CVD. The purpose of this study is to examine the impact of gout on incident CVD. (2) Participants reporting the use of gout-specific medications (urate lowering drugs or colchicine) were compared with non-users. Kaplan\u2013Meier survival curves and multivariable models to control for known CV risk factors evaluated hazard ratios (HR) between participants taking gout medications versus those not taking gout medications. (3) For the 6734 participants, analyses were stratified by gender owing to a gout-gender interaction. For the 164 male and 59 female participants taking gout medications, Kaplan\u2013Meier (unadjusted) survival curves demonstrate that participants taking gout medications have higher rates of CVD than participants not taking gout medications, particularly for women. After controlling for known CV risk factors, the adjusted HR for female participants taking gout medications was 1.79 (0.99, 3.23), p = 0.05; the adjusted HR for male participants on gout medications was 1.20 (0.81, 1.77), p = 0.36; (4) Participants treated for gout in this study have many comorbid conditions with known CVD risk factors, making it difficult to confirm the independent effect of gout on CVD. There are a paucity of data on women with gout. These findings suggest that there is a clinically meaningful and potentially greater risk of CVD among women with gout as compared to men.<\/jats:p>","DOI":"10.3390\/gucdd1020009","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T03:49:06Z","timestamp":1683690546000},"page":"89-98","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The Risk of Cardiovascular Disease among Male and Female Participants Treated for Gout in the Multi-Ethnic Study of Atherosclerosis (MESA)"],"prefix":"10.3390","volume":"1","author":[{"given":"Surbhi","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA"}]},{"given":"Elizabeth","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA"}]},{"given":"Sharon Stein","family":"Merkin","sequence":"additional","affiliation":[{"name":"Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA"}]},{"given":"Maureen","family":"McMahon","sequence":"additional","affiliation":[{"name":"Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA"}]},{"given":"Karol E.","family":"Watson","sequence":"additional","affiliation":[{"name":"Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8419-7538","authenticated-orcid":false,"given":"John D.","family":"FitzGerald","sequence":"additional","affiliation":[{"name":"Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3136","DOI":"10.1002\/art.30520","article-title":"Prevalence of gout and hyperuricemia in the US general population: The National Health and Nutrition Examination Survey 2007\u20132008","volume":"63","author":"Zhu","year":"2011","journal-title":"Arthritis Rheum."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0895-4356(88)90127-8","article-title":"Gout and coronary heart disease: The Framingham Study","volume":"41","author":"Abbott","year":"1988","journal-title":"J. Clin. Epidemiol."},{"key":"ref_3","first-page":"1","article-title":"Coronary infarction and gout","volume":"139","author":"Adner","year":"1951","journal-title":"Acta Med. Scand."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1001\/archinte.168.10.1104","article-title":"Long-term cardiovascular mortality among middle-aged men with gout","volume":"168","author":"Krishnan","year":"2008","journal-title":"Arch. Intern. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"R10","DOI":"10.1186\/ar3684","article-title":"Hyperuricemia and untreated gout are poor prognostic markers among those with a recent acute myocardial infarction","volume":"14","author":"Krishnan","year":"2012","journal-title":"Arthritis Res. Ther."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e000282","DOI":"10.1136\/bmjopen-2011-000282","article-title":"Gout and the risk for incident heart failure and systolic dysfunction","volume":"2","author":"Krishnan","year":"2012","journal-title":"BMJ Open"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1001\/archinte.165.7.742","article-title":"Obesity, weight change, hypertension, diuretic use, and risk of gout in men: The health professionals follow-up study","volume":"165","author":"Choi","year":"2005","journal-title":"Arch. Intern. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"R66","DOI":"10.1186\/ar3322","article-title":"Hyperuricemia and the risk for subclinical coronary atherosclerosis--data from a prospective observational cohort study","volume":"13","author":"Krishnan","year":"2011","journal-title":"Arthritis Res. Ther."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1136\/ard.38.2.101","article-title":"Prevalence and incidence of the diagnosis of gout in Great Britain","volume":"38","author":"Currie","year":"1979","journal-title":"Ann. Rheum. Dis."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Harrold, L.R., Etzel, C.J., Gibofsky, A., Kremer, J.M., Pillinger, M.H., Saag, K.G., Schlesinger, N., Terkeltaub, R., Cox, V., and Greenberg, J.D. (2017). Sex differences in gout characteristics: Tailoring care for women and men. BMC Musculoskelet. Disord., 18.","DOI":"10.1186\/s12891-017-1465-9"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1136\/ard.2009.122770","article-title":"Independent impact of gout on the risk of acute myocardial infarction among elderly women: A population-based study","volume":"69","author":"Rahman","year":"2010","journal-title":"Ann. Rheum. Dis."},{"key":"ref_12","first-page":"663","article-title":"Gender-specific associations between coronary heart disease and other chronic diseases: Cross-sectional evaluation of national survey data from adult residents of Germany","volume":"16","author":"Murray","year":"2019","journal-title":"J. Geriatr. Cardiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/ard.2011.200523","article-title":"Mortality due to coronary heart disease and kidney disease among middle-aged and elderly men and women with gout in the Singapore Chinese Health Study","volume":"71","author":"Teng","year":"2012","journal-title":"Ann. Rheum. Dis."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1093\/aje\/kwf113","article-title":"Multi-Ethnic Study of Atherosclerosis: Objectives and design","volume":"156","author":"Bild","year":"2002","journal-title":"Am. J. Epidemiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/art.22474","article-title":"Validity of gout diagnoses in administrative data","volume":"57","author":"Harrold","year":"2007","journal-title":"Arthritis Rheum."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1093\/rheumatology\/kes147","article-title":"Potential unmet need for gout diagnosis and treatment: Capture-recapture analysis of a national administrative dataset","volume":"51","author":"Jackson","year":"2012","journal-title":"Rheumatology"},{"key":"ref_17","first-page":"2403","article-title":"Epidemiology of gout: Is the incidence rising?","volume":"29","author":"Arromdee","year":"2002","journal-title":"J. Rheumatol."},{"key":"ref_18","first-page":"1582","article-title":"Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population","volume":"31","author":"Wallace","year":"2004","journal-title":"J. Rheumatol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1093\/rheumatology\/ker361","article-title":"National prevalence of gout derived from administrative health data in Aotearoa New Zealand","volume":"51","author":"Winnard","year":"2012","journal-title":"Rheumatology"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/BOR.0000000000000141","article-title":"Overcoming adherence issues and other barriers to optimal care in gout","volume":"27","author":"Harrold","year":"2015","journal-title":"Curr. Opin. Rheumatol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1016\/j.numecd.2021.09.011","article-title":"Inequalities in enrollment of women and racial minorities in trials testing uric acid lowering drugs","volume":"31","author":"Fogacci","year":"2021","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"ref_22","first-page":"293","article-title":"Cardiovascular disease in women","volume":"70","author":"Duvall","year":"2003","journal-title":"Mt. Sinai. J. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1161\/01.CIR.97.21.2110","article-title":"Effect of risk factors on the mechanism of acute thrombosis and sudden coronary death in women","volume":"97","author":"Burke","year":"1998","journal-title":"Circulation"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.atherosclerosis.2015.01.017","article-title":"Sex differences in coronary artery disease: Pathological observations","volume":"239","author":"Yahagi","year":"2015","journal-title":"Atherosclerosis"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.maturitas.2021.08.002","article-title":"Should we be more aware of gender aspects in hyperuricemia? Analysis of the population-based German health interview and examination survey for adults (DEGS1)","volume":"153","author":"Engel","year":"2021","journal-title":"Maturitas"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"2615147","DOI":"10.1155\/2020\/2615147","article-title":"Hyperuricemia is a Risk Factor for One-Year Overall Survival in Elderly Female Patients with Acute Coronary Syndrome","volume":"2020","author":"Tai","year":"2020","journal-title":"Cardiovasc. Ther."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/rheumatology\/kes169","article-title":"Risk of myocardial infarction among patients with gout: A nationwide population-based study","volume":"52","author":"Kuo","year":"2013","journal-title":"Rheumatology"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1161\/CIRCULATIONAHA.107.703389","article-title":"Independent impact of gout on mortality and risk for coronary heart disease","volume":"116","author":"Choi","year":"2007","journal-title":"Circulation"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1002\/art.22014","article-title":"Gout and the risk of acute myocardial infarction","volume":"54","author":"Krishnan","year":"2006","journal-title":"Arthritis Rheum."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"265","DOI":"10.2147\/VHRM.S4265","article-title":"Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress","volume":"5","author":"George","year":"2009","journal-title":"Vasc. Health Risk Manag."},{"key":"ref_31","first-page":"A12843","article-title":"Abstract 12843: A Novel Approach For Uric Acid Crystal Detection in Human Coronary Plaques Ex-Vivo With Cross-Polarized Micro-OCT","volume":"140","author":"Nishimiya","year":"2019","journal-title":"Circulation"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1056\/NEJMoa1707914","article-title":"Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease","volume":"377","author":"Ridker","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"ref_33","first-page":"24832","article-title":"Causal mediation analysis of the relationship of canakinumab\u2019s effect against subsequent gout flares and high-sensitivity C-reactive protein in CANTOS","volume":"75","author":"Yoshida","year":"2021","journal-title":"Arthritis Care Res."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1056\/NEJMoa1912388","article-title":"Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction","volume":"381","author":"Tardif","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s40801-015-0016-7","article-title":"Role of Community Pharmacies for the Detection of Potentially Inappropriate Xanthine Oxidase Inhibitor Prescriptions","volume":"2","author":"Pasina","year":"2015","journal-title":"Drugs Real. World Outcomes"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1136\/annrheumdis-2022-222387","article-title":"Risk of cardiovascular events in patients having had acute calcium pyrophosphate crystal arthritis","volume":"81","author":"Tedeschi","year":"2022","journal-title":"Ann. Rheum. Dis."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1002\/acr.22469","article-title":"Gout, urate-lowering therapy, and uric acid levels among adults in the United States","volume":"67","author":"Juraschek","year":"2015","journal-title":"Arthritis Care Res."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1002\/art.40807","article-title":"Contemporary Prevalence of Gout and Hyperuricemia in the United States and Decadal Trends: The National Health and Nutrition Examination Survey, 2007\u20132016","volume":"71","author":"Yokose","year":"2019","journal-title":"Arthritis Rheumatol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10067-014-2783-z","article-title":"Management of gout in general practice\u2014A systematic review","volume":"34","author":"Jeyaruban","year":"2015","journal-title":"Clin. Rheumatol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1056\/NEJMoa1710895","article-title":"Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout","volume":"378","author":"White","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1161\/CIRCRESAHA.116.309115","article-title":"Decline in Cardiovascular Mortality: Possible Causes and Implications","volume":"120","author":"Mensah","year":"2017","journal-title":"Circ. Res."}],"container-title":["Gout, Urate, and Crystal Deposition Disease"],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2813-4583\/1\/2\/9\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:32:07Z","timestamp":1760124727000},"score":17.216955,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2813-4583\/1\/2\/9"}},"issued":{"date-parts":[[2023,5,9]]},"references-count":41,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,6]]}},"alternative-id":["gucdd1020009"],"URL":"https:\/\/doi.org\/10.3390\/gucdd1020009","ISSN":["2813-4583"],"issn-type":[{"type":"electronic","value":"2813-4583"}],"published":{"date-parts":[[2023,5,9]]}},{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:42:17Z","timestamp":1760114537602,"version":"build-2065373602"},"reference-count":28,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T00:00:00Z","timestamp":1726704000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-19-P3IA-0001","RO1 HL098433","HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","R24 HL114473","75N92019R002","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"],"award-info":[{"award-number":["ANR-19-P3IA-0001","RO1 HL098433","HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","R24 HL114473","75N92019R002","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NIH-NHLBI Association of Sleep Disorders with Cardiovascular Health across Ethnic Groups","award":["ANR-19-P3IA-0001","RO1 HL098433","HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","R24 HL114473","75N92019R002","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"],"award-info":[{"award-number":["ANR-19-P3IA-0001","RO1 HL098433","HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","R24 HL114473","75N92019R002","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"]}]},{"name":"National Heart, Lung, and Blood Institute","award":["ANR-19-P3IA-0001","RO1 HL098433","HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","R24 HL114473","75N92019R002","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"],"award-info":[{"award-number":["ANR-19-P3IA-0001","RO1 HL098433","HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","R24 HL114473","75N92019R002","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"]}]},{"name":"NCATS","award":["ANR-19-P3IA-0001","RO1 HL098433","HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","R24 HL114473","75N92019R002","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"],"award-info":[{"award-number":["ANR-19-P3IA-0001","RO1 HL098433","HHSN268201500003I","N01-HC-95159","N01-HC-95160","N01-HC-95161","N01-HC-95162","N01-HC-95163","N01-HC-95164","N01-HC-95165","N01-HC-95166","N01-HC-95167","N01-HC-95168","N01-HC-95169","R24 HL114473","75N92019R002","UL1-TR-000040","UL1-TR-001079","UL1-TR-001420"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Introduction: Accurately detecting arousal events during sleep is essential for evaluating sleep quality and diagnosing sleep disorders, such as sleep apnea\/hypopnea syndrome. While the American Academy of Sleep Medicine guidelines associate arousal events with electroencephalogram (EEG) signal variations, EEGs are often not recorded during home sleep testing (HST) using wearable devices or smartphone applications. Objectives: The primary objective of this study was to explore the potential of alternatively relying on combinations of easily measurable physiological signals during HST for arousal detection where EEGs are not recorded. Methods: We conducted a data-driven retrospective study following an incremental device-agnostic analysis approach, where we simulated a limited-channel setting using polysomnography data and used deep learning to automate the detection task. During the analysis, we tested multiple signal combinations to evaluate their potential effectiveness. We trained and evaluated the model on the Multi-Ethnic Study of Atherosclerosis dataset. Results: The results demonstrated that combining multiple signals significantly improved performance compared with single-input signal models. Notably, combining thoracic effort, heart rate, and a wake\/sleep indicator signal achieved competitive performance compared with the state-of-the-art DeepCAD model using electrocardiogram as input with an average precision of 61.59% and an average recall of 56.46% across the test records. Conclusions: This study demonstrated the potential of combining easy-to-record HST signals to characterize the autonomic markers of arousal better. It provides valuable insights to HST device designers on signals that improve EEG-free arousal detection.<\/jats:p>","DOI":"10.3390\/diagnostics14182077","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T11:51:46Z","timestamp":1726746706000},"page":"2077","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Combining Signals for EEG-Free Arousal Detection during Home Sleep Testing: A Retrospective Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3090-417X","authenticated-orcid":false,"given":"Safa","family":"Boudabous","sequence":"first","affiliation":[{"name":"CEREMADE, CNRS-UMR 7534, Universit\u00e9 Paris-Dauphine PSL, 75016 Paris, France"}]},{"given":"Juliette","family":"Millet","sequence":"additional","affiliation":[{"name":"Mitral, Apneal, 75013 Paris, France"}]},{"given":"Emmanuel","family":"Bacry","sequence":"additional","affiliation":[{"name":"CEREMADE, CNRS-UMR 7534, Universit\u00e9 Paris-Dauphine PSL, 75016 Paris, France"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1093\/sleep\/24.8.895","article-title":"Acute cardiovascular responses to arousal from non-REM sleep during normoxia and hypoxia","volume":"24","author":"Catcheside","year":"2001","journal-title":"Sleep"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1093\/sleep\/22.8.1059","article-title":"Respiratory paradox as an indicator of arousal from non-REM sleep","volume":"22","author":"Eaton","year":"1999","journal-title":"Sleep"},{"key":"ref_3","unstructured":"Shneerson, J. (2005). Sleep Medicine: A Guide to Sleep and Its Disorders, Wiley."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Yeh, E., Wong, E., Tsai, C.W., Gu, W., Chen, P.L., Leung, L., Wu, I.C., Strohl, K.P., Folz, R.J., and Yar, W. (2021). Detection of obstructive sleep apnea using Belun Sleep Platform wearable with neural network-based algorithm and its combined use with STOP-Bang questionnaire. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0258040"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.1183\/20734735.008817","article-title":"The use of tracheal sounds for the diagnosis of sleep apnoea","volume":"13","author":"Penzel","year":"2017","journal-title":"Breathe"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Kukwa, W., Lis, T., \u0141aba, J., Mitchell, R.B., and M\u0142y\u0144czak, M. (2022). Sleep position detection with a wireless audio-motion sensor\u2014A validation study. Diagnostics, 12.","DOI":"10.3390\/diagnostics12051195"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Rofouei, M., Sinclair, M., Bittner, R., Blank, T., Saw, N., DeJean, G., and Heffron, J. (2011, January 23\u201325). A non-invasive wearable neck-cuff system for real-time sleep monitoring. Proceedings of the 2011 International Conference on Body Sensor Networks, Dallas, TX, USA.","DOI":"10.1109\/BSN.2011.38"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s11325-022-02599-x","article-title":"Comparative study of a wearable intelligent sleep monitor and polysomnography monitor for the diagnosis of obstructive sleep apnea","volume":"27","author":"Xu","year":"2023","journal-title":"Sleep Breath."},{"key":"ref_9","unstructured":"Frija, J., Millet, J., Bequignon, E., Covali, A., Cathelain, G., Houenou, J., Benzaquen, H., Geoffroy, P.A., Bacry, E., and Grajoszex, M. (2024). Validation of a new, minimally-invasive, software smartphone device to predict sleep apnea and its severity: Transversal study. arXiv."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0013-4694(64)90109-9","article-title":"Responses to auditory stimulation, sleep loss and the EEG stages of sleep","volume":"16","author":"Williams","year":"1964","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1164\/ajrccm.152.3.7663777","article-title":"Arousal responses from apneic events during non-rapid-eye-movement sleep","volume":"152","author":"Rees","year":"1995","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"S189","DOI":"10.1093\/sleep\/19.suppl_10.189","article-title":"Respiratory and electrocortical responses to acoustic stimulation","volume":"19","author":"Carley","year":"1996","journal-title":"Sleep"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1136\/thx.48.12.1242","article-title":"Identification of sleep disruption and sleep disordered breathing from the systolic blood pressure profile","volume":"48","author":"Davies","year":"1993","journal-title":"Thorax"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1365-2869.2008.00720.x","article-title":"Arousal in obstructive sleep apnoea patients is associated with ECG RR and QT interval shortening and PR interval lengthening","volume":"18","author":"Smith","year":"2009","journal-title":"J. Sleep Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1152\/japplphysiol.01095.2002","article-title":"Cardiovascular variability after arousal from sleep: Time-varying spectral analysis","volume":"95","author":"Blasi","year":"2003","journal-title":"J. Appl. Physiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1093\/sleep\/25.5.541","article-title":"Autonomic arousal index: An automated detection based on peripheral arterial tonometry","volume":"25","author":"Pillar","year":"2002","journal-title":"Sleep"},{"key":"ref_17","unstructured":"Foussier, J., Fonseca, P., Long, X., Misgeld, B., and Leonhardt, S. (2013, January 22\u201325). Combining HRV features for automatic arousal detection. Proceedings of the Computing in Cardiology 2013, Zaragoza, Spain."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1093\/sleep\/30.10.1349","article-title":"An ECG-based algorithm for the automatic identification of autonomic activations associated with cortical arousal","volume":"30","author":"Basner","year":"2007","journal-title":"Sleep"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"zsy006","DOI":"10.1093\/sleep\/zsy006","article-title":"Automatic, electrocardiographic-based detection of autonomic arousals and their association with cortical arousals, leg movements, and respiratory events in sleep","volume":"41","author":"Olsen","year":"2018","journal-title":"Sleep"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Ehrlich, F., Bender, J., Malberg, H., and Goldammer, M. (2022, January 4\u20137). Automatic Sleep Arousal Detection Using Heart Rate From a Single-Lead Electrocardiogram. Proceedings of the 2022 Computing in Cardiology (CinC), Tampere, Finland.","DOI":"10.22489\/CinC.2022.080"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"zsaa120","DOI":"10.1093\/sleep\/zsaa120","article-title":"A deep learning-based algorithm for detection of cortical arousal during sleep","volume":"43","author":"Li","year":"2020","journal-title":"Sleep"},{"key":"ref_22","first-page":"877","article-title":"Racial\/ethnic differences in sleep disturbances: The Multi-Ethnic Study of Atherosclerosis (MESA)","volume":"38","author":"Chen","year":"2015","journal-title":"Sleep"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1093\/jamia\/ocy064","article-title":"The National Sleep Research Resource: Towards a sleep data commons","volume":"25","author":"Zhang","year":"2018","journal-title":"J. Am. Med. Inform. Assoc."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1162\/neco.1997.9.8.1735","article-title":"Long Short-Term Memory","volume":"9","author":"Hochreiter","year":"1997","journal-title":"Neural Comput."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1109\/5.58337","article-title":"Backpropagation through time: What it does and how to do it","volume":"78","author":"Werbos","year":"1990","journal-title":"Proc. IEEE"},{"key":"ref_26","unstructured":"Kingma, D.P., and Ba, J. (2014). Adam: A method for stochastic optimization. arXiv."},{"key":"ref_27","unstructured":"Berg-Kirkpatrick, T., Burkett, D., and Klein, D. (2012, January 12\u201314). An empirical investigation of statistical significance in NLP. Proceedings of the 2012 Joint Conference on Empirical Methods in Natural Language Processing and Computational Natural Language Learning, Jeju Island, Republic of Korea."},{"key":"ref_28","first-page":"65","article-title":"A simple sequentially rejective multiple test procedure","volume":"6","author":"Holm","year":"1979","journal-title":"Scand. J. 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UL1-TR-001420"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100007880","name":"Johns Hopkins University","doi-asserted-by":"crossref","award":["Blumenthal Scholars Award in Preventive Cardiology"],"award-info":[{"award-number":["Blumenthal Scholars Award in Preventive Cardiology"]}],"id":[{"id":"10.13039\/100007880","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100007880","name":"Johns Hopkins University","doi-asserted-by":"publisher","award":["Blumenthal Scholars Award in Preventive Cardiology"],"award-info":[{"award-number":["Blumenthal Scholars Award in Preventive Cardiology"]}],"id":[{"id":"10.13039\/100007880","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Johns Hopkins University School of Medicine","award":["Dean\u2019s Research Fund"],"award-info":[{"award-number":["Dean\u2019s Research Fund"]}]},{"name":"Laboratory Corporation of America Holdings"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Emerging evidence has implicated that inflammation contributes to the pathogenesis of atrial fibrillation (AF). GlycA is a novel marker of systemic inflammation with low intra-individual variability and high analytic precision. GlycA has been associated with incident cardiovascular disease (CVD) independent of other inflammatory markers. However, whether GlycA is associated with AF, specifically, has yet to be established. We examined the association between GlycA and AF in a multi-ethnic cohort.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>We studied 6,602 MESA participants aged 45\u201385, with no clinical CVD at baseline, with data on GlycA and incident AF. We used multivariable-adjusted Cox models to evaluate the association between GlycA and incident AF. We also examined other inflammatory markers [high-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL6) and fibrinogen] and incident AF for comparison.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The mean (SD) age was 62 (10) years, 53% women. The mean plasma GlycA was 381 (62) \u03bcmol\/L. Over median follow-up of 12.9 years, 869 participants experienced AF. There was no statistically significant association between GlycA and incident AF after adjusting for sociodemographics, CVD risk factors, and other inflammatory markers [Hazard Ratio (95% CI) per 1 SD increment in GlycA: 0.97 (0.88\u20131.06)]. Neither hsCRP nor fibrinogen was associated with incident AF in same model. In contrast, IL-6 was independently associated with incident AF [HR 1.12 per 1 SD increment (1.05\u20131.19)].<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Although GlycA has been associated with other CVD types, we found that GlycA was not associated with AF. More research will be required to understand why IL-6 was associated with AF but not GlycA.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec005\">\n<jats:title>Clinical trial registration<\/jats:title>\n<jats:p>MESA is not a clinical trial. However, the cohort is registered at: URL: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT00005487\" xlink:type=\"simple\">https:\/\/clinicaltrials.gov\/ct2\/show\/NCT00005487<\/jats:ext-link> Unique identifier: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT00005487\" xlink:type=\"simple\">NCT00005487<\/jats:ext-link>.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0248644","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T15:20:58Z","timestamp":1616685658000},"page":"e0248644","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["The association of novel inflammatory marker GlycA and incident atrial fibrillation in the Multi-Ethnic Study of Atherosclerosis 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However, the evidence is lacking on the role of family dysfunction during sensitive developmental periods in both boys and girls from racial and ethnic minority groups. This study aimed to determine the effect of family dysfunction on the timing of pubertal maturation among US Hispanic\/Latino children and adolescents. Participants were 1466 youths (50% female; ages 8\u201316 years) from the Hispanic Community Children\u2019s Health Study\/Study of Latino Youth (SOL Youth). Pubertal maturation was measured using self-administered Pubertal Development Scale (PDS) items for boys and girls. Family dysfunction included measures of single-parent family structure, unhealthy family functioning, low parental closeness, and neglectful parenting style. We used multivariable ordinal logistic and linear regression analyses to examine the associations between family dysfunction and pubertal maturation (individual and cumulative measures), with adjustment for childhood BMI and socioeconomic factors, design effects (strata and clustering), and sample weights. Multivariable models of individual PDS items showed that family dysfunction was negatively associated with growth in height (OR = 0.66, 95% CI: 0.44, 0.99) in girls; no associations were found in boys. In the assessment of cumulative PDS scores, family dysfunction was associated with a lower average pubertal maturation score (b = \u22120.63, 95% CI: \u22121.21, \u22120.05) in boys, while no associations were found in girls. Pubertal timing lies at the intersection of associations between childhood adversity and adult health and warrants further investigation to understand the factors affecting timing and differences across sex and sociocultural background.<\/jats:p>","DOI":"10.3390\/ijerph22040576","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T07:41:51Z","timestamp":1744270911000},"page":"576","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Family Functioning and Pubertal Maturation in Hispanic\/Latino Children from the HCHS\/SOL Youth"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3341-4464","authenticated-orcid":false,"given":"Ayana K.","family":"April-Sanders","sequence":"first","affiliation":[{"name":"Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ 08854, USA"}]},{"given":"Parisa","family":"Tehranifar","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY 10032, USA"},{"name":"Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA"}]},{"given":"Mary Beth","family":"Terry","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY 10032, USA"},{"name":"Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA"}]},{"given":"Danielle M.","family":"Crookes","sequence":"additional","affiliation":[{"name":"Department of Health Sciences and College of Social Sciences and Humanities, Department of Anthropology and Sociology, Bouv\u00e9 College of Health Sciences, Northeastern University, Boston, MA 02115, USA"}]},{"given":"Carmen R.","family":"Isasi","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY 10461, USA"},{"name":"Department of Pediatrics, Albert Einstein College of Medicine, New York, NY 10461, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3678-5888","authenticated-orcid":false,"given":"Linda C.","family":"Gallo","sequence":"additional","affiliation":[{"name":"Department of Psychology, San Diego State University, San Diego, CA 92182, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6985-423X","authenticated-orcid":false,"given":"Lindsay","family":"Fernandez-Rhodes","sequence":"additional","affiliation":[{"name":"Department of Biobehavioral Health, College of Health and Human Development, Pennsylvania State University, University Park, PA 16802, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2906-0261","authenticated-orcid":false,"given":"Krista M.","family":"Perreira","sequence":"additional","affiliation":[{"name":"Department of Social Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA"}]},{"given":"Martha L.","family":"Daviglus","sequence":"additional","affiliation":[{"name":"Institute of Minority Health Research, University of Illinois College of Medicine, Chicago, IL 60612, USA"}]},{"given":"Shakira F.","family":"Suglia","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.dr.2018.05.001","article-title":"Neither antecedent nor consequence: Developmental integration of chronic stress, pubertal timing, and conditionally adapted stress response","volume":"48","author":"Joos","year":"2018","journal-title":"Dev. 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Cancer"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1037\/dev0000017","article-title":"Early adversity, elevated stress physiology, accelerated sexual maturation, and poor health in females","volume":"51","author":"Belsky","year":"2015","journal-title":"Dev. Psychol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1146\/annurev-psych-122216-011732","article-title":"Developmental Adaptation to Stress: An Evolutionary Perspective","volume":"70","author":"Ellis","year":"2019","journal-title":"Annu. Rev. Psychol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1097\/00004583-199712000-00026","article-title":"Is psychopathology associated with the timing of pubertal development?","volume":"36","author":"Graber","year":"1997","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"647","DOI":"10.2307\/1131166","article-title":"Childhood experience, interpersonal development, and reproductive strategy: And evolutionary theory of socialization","volume":"62","author":"Belsky","year":"1991","journal-title":"Child Dev."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Day, F.R., Elks, C.E., Murray, A., Ong, K.K., and Perry, J.R. (2015). Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: The UK Biobank study. Sci. Rep., 5.","DOI":"10.1038\/srep11208"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1037\/0033-2909.130.6.920","article-title":"Timing of pubertal maturation in girls: An integrated life history approach","volume":"130","author":"Ellis","year":"2004","journal-title":"Psychol. Bull."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1037\/0022-3514.61.1.157","article-title":"Individual differences are accentuated during periods of social change: The sample case of girls at puberty","volume":"61","author":"Caspi","year":"1991","journal-title":"J. Pers. Soc. Psychol."},{"key":"ref_15","unstructured":"Adelson, J. (1980). Perspectives on adolescence from longitudinal research. Handbook of Adolescent Psychology, John Wiley & Sons."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"S7.e1-6","DOI":"10.1016\/j.jpeds.2009.04.050","article-title":"Prolonged juvenile States and delay of cardiovascular and metabolic risk factors: The Fels Longitudinal study","volume":"155","author":"Sun","year":"2009","journal-title":"J. Pediatr."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1016\/j.neubiorev.2010.11.007","article-title":"The Adaptive Calibration Model of stress responsivity","volume":"35","author":"Ellis","year":"2011","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Godoy, L.D., Rossignoli, M.T., Delfino-Pereira, P., Garcia-Cairasco, N., and de Lima Umeoka, E.H. (2018). A Comprehensive Overview on Stress Neurobiology: Basic Concepts and Clinical Implications. Front. Behav. Neurosci., 12.","DOI":"10.3389\/fnbeh.2018.00127"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.biopsycho.2013.02.005","article-title":"Childhood adversity and pubertal timing: Understanding the origins of adulthood cardiovascular risk","volume":"93","author":"Bleil","year":"2013","journal-title":"Biol. Psychol."},{"key":"ref_20","first-page":"49","article-title":"Factors affecting onset of puberty in Denizli province in Turkey","volume":"51","author":"Semiz","year":"2009","journal-title":"Turk. J. Pediatr."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s10578-004-3489-2","article-title":"Precocious puberty in adolescent girls: A biomarker of later psychosocial adjustment problems","volume":"36","author":"Tremblay","year":"2005","journal-title":"Child Psychiatry Hum. Dev."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1007\/s10964-011-9638-6","article-title":"The family antecedents and the subsequent outcomes of early puberty","volume":"40","author":"Arim","year":"2011","journal-title":"J. Youth Adolesc."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1038\/ijo.2012.177","article-title":"Pubertal timing and adult obesity and cardiometabolic risk in women and men: A systematic review and meta-analysis","volume":"37","author":"Prentice","year":"2013","journal-title":"Int. J. Obes."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1542\/peds.2012-3773","article-title":"Onset of breast development in a longitudinal cohort","volume":"132","author":"Biro","year":"2013","journal-title":"Pediatrics"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1111\/obr.12587","article-title":"Birth weight, early life weight gain and age at menarche: A systematic review of longitudinal studies","volume":"18","author":"Juul","year":"2017","journal-title":"Obes. Rev."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1365-2605.2005.00602.x","article-title":"Influence of obesity on timing of puberty","volume":"29","author":"Biro","year":"2006","journal-title":"Int. J. Androl."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1038\/ijo.2014.116","article-title":"Association between obesity and sexual maturation in Chinese children: A muticenter study","volume":"38","author":"Dai","year":"2014","journal-title":"Int. J. Obes."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1080\/00207390500434135","article-title":"Association between overweight and early sexual maturation in Portuguese boys and girls","volume":"33","author":"Ribeiro","year":"2006","journal-title":"Ann. Hum. Biol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1542\/peds.110.5.903","article-title":"Is obesity associated with early sexual maturation? A comparison of the association in American boys versus girls","volume":"110","author":"Wang","year":"2002","journal-title":"Pediatrics"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"e1173","DOI":"10.1542\/peds.2011-2456","article-title":"Cumulative social risk and obesity in early childhood","volume":"129","author":"Suglia","year":"2012","journal-title":"Pediatrics"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1093\/jpepsy\/jsaa082","article-title":"Early Life Adversity and Pubertal Timing: Implications for Cardiometabolic Health","volume":"46","author":"Bleil","year":"2020","journal-title":"J. Pediatr. Psychol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/ijo.2013.213","article-title":"The relationship between family functioning and child and adolescent overweight and obesity: A systematic review","volume":"38","author":"Halliday","year":"2014","journal-title":"Int. J. Obes."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.adolescence.2004.10.008","article-title":"Age at puberty and father absence in a national probability sample","volume":"28","author":"Bogaert","year":"2005","journal-title":"J. Adolesc."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1111\/j.1467-8624.2007.01092.x","article-title":"Family environments, adrenarche, and sexual maturation: A longitudinal test of a life history model","volume":"78","author":"Ellis","year":"2007","journal-title":"Child Dev."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"47","DOI":"10.2307\/1130900","article-title":"Childhood experience and the onset of menarche: A test of a sociobiological model","volume":"63","author":"Moffitt","year":"1992","journal-title":"Child Dev."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jadohealth.2010.07.032","article-title":"Father absence, body mass index, and pubertal timing in girls: Differential effects by family income and ethnicity","volume":"48","author":"Deardorff","year":"2011","journal-title":"J. Adolesc. Health"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Zhang, L., Zhang, D., and Sun, Y. (2019). Adverse Childhood Experiences and Early Pubertal Timing Among Girls: A Meta-Analysis. Int. J. Environ. Res. Public Health, 16.","DOI":"10.3390\/ijerph16162887"},{"key":"ref_38","unstructured":"Hales, C.M., Carroll, M.D., Fryar, C.D., and Ogden, C.L. (2017). Prevalence of Obesity Among Adults and Youth: United States, 2015\u20132016, National Center for Health Statistics. NCHS data brief, no 288."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1037\/lat0000054","article-title":"Health issues in Hispanic\/Latino youth","volume":"4","author":"Isasi","year":"2016","journal-title":"J. Lat.\/O Psychol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"3793","DOI":"10.1080\/00036846.2011.581219","article-title":"Poverty among minorities in the United States: Explaining the racial poverty gap for Blacks and Latinos","volume":"44","year":"2012","journal-title":"Appl. Econ."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1158\/1055-9965.EPI-17-0496","article-title":"Childhood Socioeconomic Position and Pubertal Onset in a Cohort of Multiethnic Girls: Implications for Breast Cancer","volume":"26","author":"Hiatt","year":"2017","journal-title":"Cancer Epidemiol. Biomark. Prev."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.annepidem.2010.08.006","article-title":"The Impact of Socioeconomic Status across Early Life on Age at Menarche Among a Racially Diverse Population of Girls","volume":"20","author":"Tehranifar","year":"2010","journal-title":"Ann. Epidemiol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1177\/0192513X13477379","article-title":"Measuring Acculturation Gap Conflicts among Hispanics: Implications for Psychosocial and Academic Adjustment","volume":"35","author":"Dennis","year":"2014","journal-title":"J. Fam. Issues"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Houghton, L.C., Paniagua-Avila, A., Hua, S., Terry, M.B., McDonald, J.A., Ulanday, K.T., van Horn, L., Carnethon, M.R., and Isasi, C.R. (2023). Immigrant generation status and its association with pubertal timing and tempo among Hispanic girls and boys. Am. J. Hum. Biol., 35.","DOI":"10.1002\/ajhb.23940"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1037\/lat0000084","article-title":"The role of acculturation differences and acculturation conflict in Latino family mental health","volume":"6","author":"Lawton","year":"2018","journal-title":"J. Lat.\/O Psychol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"e583","DOI":"10.1542\/peds.2009-3079","article-title":"Pubertal Assessment Method and Baseline Characteristics in a Mixed Longitudinal Study of Girls","volume":"126","author":"Biro","year":"2010","journal-title":"Pediatrics"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"100549","DOI":"10.1016\/j.ssmph.2020.100549","article-title":"Timing of puberty in boys and girls: Implications for population health","volume":"10","author":"Hoyt","year":"2020","journal-title":"SSM\u2014Popul. Health"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.yhbeh.2013.03.014","article-title":"Influences on the onset and tempo of puberty in human beings and implications for adolescent psychological development","volume":"64","author":"Lee","year":"2013","journal-title":"Horm. Behav."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/s41390-020-01264-x","article-title":"The social ecology of childhood and early life adversity","volume":"89","author":"Lopez","year":"2021","journal-title":"Pediatr. Res."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"105101","DOI":"10.1016\/j.yhbeh.2021.105101","article-title":"Family environmental antecedents of pubertal timing in girls and boys: A review and open questions","volume":"138","author":"Pham","year":"2022","journal-title":"Horm. Behav."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jadohealth.2014.10.002","article-title":"Childhood abuse and early menarche among Peruvian women","volume":"56","author":"Barrios","year":"2015","journal-title":"J. Adolesc. Health"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1097\/PSY.0000000000000817","article-title":"Childhood Adversity and Pubertal Development Among Puerto Rican Boys and Girls","volume":"82","author":"Suglia","year":"2020","journal-title":"Psychosom. Med."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1093\/aje\/kwab100","article-title":"Childhood Overweight and Obesity and Pubertal Onset Among Mexican-American Boys and Girls in the CHAMACOS Longitudinal Study","volume":"191","author":"Deardorff","year":"2021","journal-title":"Am. J. Epidemiol."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Birman, D. (2006). Measurement of the \u201cAcculturation Gap\u201d in Immigrant Families and Implications for Parent-Child Relationships. Acculturation and Parent-Child Relationships: Measurement and Development, Lawrence Erlbaum Associates Publishers.","DOI":"10.4324\/9780415963589-7"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1037\/0003-066X.48.4.400","article-title":"Family psychology and cultural diversity: Opportunities for theory, research, and application","volume":"48","author":"Szapocznik","year":"1993","journal-title":"Am. Psychol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.annepidem.2010.05.006","article-title":"Sample design and cohort selection in the Hispanic Community Health Study\/Study of Latinos","volume":"20","author":"Lavange","year":"2010","journal-title":"Ann. Epidemiol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.annepidem.2010.03.015","article-title":"Design and implementation of the Hispanic Community Health Study\/Study of Latinos","volume":"20","author":"Sorlie","year":"2010","journal-title":"Ann. Epidemiol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.annepidem.2013.08.008","article-title":"The Hispanic Community Children\u2019s Health Study\/Study of Latino Youth (SOL Youth): Design, objectives, and procedures","volume":"24","author":"Isasi","year":"2014","journal-title":"Ann. Epidemiol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/PSY.0000000000000668","article-title":"Socioeconomic Adversity, Social Resources, and Allostatic Load Among Hispanic\/Latino Youth: The Study of Latino Youth","volume":"81","author":"Gallo","year":"2019","journal-title":"Psychosom. Med."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1111\/j.1752-0606.1983.tb01497.x","article-title":"The McMASTER Family Assessment Device*","volume":"9","author":"Epstein","year":"1983","journal-title":"J. Marital. Fam. Ther."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1037\/h0080547","article-title":"A psychometric study of the McMaster Family Assessment Device in psychiatric, medical, and nonclinical samples","volume":"3","author":"Kabacoff","year":"1990","journal-title":"J. Fam. Psychol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1752-0606.1985.tb00028.x","article-title":"The McMASTER Family Assessment Device: Reliablity and Validity*","volume":"11","author":"Miller","year":"1985","journal-title":"J. Marital. Fam. Ther."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1177\/109019819802500307","article-title":"The Authoritative Parenting Index: Predicting health risk behaviors among children and adolescents","volume":"25","author":"Jackson","year":"1998","journal-title":"Health Educ. Behav."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.appet.2011.08.014","article-title":"Parent- and child-reported parenting. Associations with child weight-related outcomes","volume":"57","author":"Taylor","year":"2011","journal-title":"Appetite"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF01537962","article-title":"A self-report measure of pubertal status: Reliability, validity, and initial norms","volume":"17","author":"Petersen","year":"1988","journal-title":"J. Youth Adolesc."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1136\/adc.44.235.291","article-title":"Variations in pattern of pubertal changes in girls","volume":"44","author":"Marshall","year":"1969","journal-title":"Arch. Dis. Child."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1136\/adc.45.239.13","article-title":"Variations in the pattern of pubertal changes in boys","volume":"45","author":"Marshall","year":"1970","journal-title":"Arch. Dis. Child."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.adolescence.2005.10.001","article-title":"A comparison of self-reported puberty using the Pubertal Development Scale and the Sexual Maturation Scale in a school-based epidemiologic survey","volume":"29","author":"Bond","year":"2006","journal-title":"J. Adolesc."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"829","DOI":"10.2307\/1130220","article-title":"Validity of self-report measures of girls\u2019 pubertal status","volume":"58","author":"Warren","year":"1987","journal-title":"Child Dev."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.jadohealth.2006.05.014","article-title":"Measuring puberty","volume":"39","author":"Dorn","year":"2006","journal-title":"J. Adolesc. Health"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jadohealth.2009.02.013","article-title":"Determination of Relative Timing of Pubertal Maturation through Ordinal Logistic Modeling: Evaluation of Growth and Timing Parameters","volume":"45","author":"Huang","year":"2009","journal-title":"J. Adolesc. Health"},{"key":"ref_72","first-page":"205","article-title":"Partial Proportional Odds Models for Ordinal Response Variables","volume":"39","author":"Peterson","year":"1990","journal-title":"J. R. Stat. Soc. Ser. C (Appl. Stat.)"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jadohealth.2012.06.006","article-title":"Childhood abuse and age at menarche","volume":"52","author":"Wright","year":"2013","journal-title":"J. Adolesc. Health"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jadohealth.2016.09.008","article-title":"Childhood Sexual Abuse and Early Timing of Puberty","volume":"60","author":"Noll","year":"2017","journal-title":"J. Adolesc. Health"},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"April-Sanders, A.K., Tehranifar, P., Argov, E.L., Suglia, S.F., Rodriguez, C.B., and McDonald, J.A. (2021). Influence of Childhood Adversity and Infection on Timing of Menarche in a Multiethnic Sample of Women. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18084080"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1017\/S0954579421001838","article-title":"Why and how does early adversity influence development? Toward an integrated model of dimensions of environmental experience","volume":"34","author":"Ellis","year":"2022","journal-title":"Dev. Psychopathol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1177\/0963721416655883","article-title":"Beyond Cumulative Risk:A Dimensional Approach to Childhood Adversity","volume":"25","author":"McLaughlin","year":"2016","journal-title":"Curr. Dir. Psychol. Sci."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1177\/1745691621992346","article-title":"The Value of Dimensional Models of Early Experience: Thinking Clearly About Concepts and Categories","volume":"16","author":"McLaughlin","year":"2021","journal-title":"Perspect. Psychol. Sci."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1007\/s10802-023-01114-4","article-title":"Challenges with Latent Variable Approaches to Operationalizing Dimensions of Childhood adversity\u2014A Commentary on Sisitsky et al. (2023)","volume":"51","author":"McLaughlin","year":"2023","journal-title":"Res. Child Adolesc. Psychopathol."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000521074","article-title":"Stress and Growth in Children and Adolescents","volume":"96","author":"Mousikou","year":"2023","journal-title":"Horm. Res. Paediatr."},{"key":"ref_81","doi-asserted-by":"crossref","unstructured":"Zhong, D., Reid, B.M., Donzella, B., Miller, B.S., and Gunnar, M.R. (2022). Early-life stress and current stress predict BMI and height growth trajectories in puberty. Dev. Psychobiol., 64.","DOI":"10.1002\/dev.22342"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1136\/adc.77.4.326","article-title":"Family conflict and slow growth","volume":"77","author":"Montgomery","year":"1997","journal-title":"Arch. Dis. Child."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.chiabu.2016.12.010","article-title":"Height deficit in early adulthood following substantiated childhood maltreatment: A birth cohort study","volume":"64","author":"Abajobir","year":"2017","journal-title":"Child Abus. Negl."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"7","DOI":"10.14310\/horm.2002.1217","article-title":"Psychological and metabolic stress: A recipe for accelerated cellular aging?","volume":"8","author":"Epel","year":"2009","journal-title":"Hormones"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1136\/bmj.330.7486.301","article-title":"Adolescent development","volume":"330","author":"Christie","year":"2005","journal-title":"BMJ"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1002\/ajhb.1123","article-title":"Effect of familial distress on growth and maturation of girls: A longitudinal study","volume":"13","author":"Hulanicka","year":"2001","journal-title":"Am. J. Hum. Biol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1007\/s11113-017-9441-5","article-title":"Race Disparities in Pubertal Timing: Implications for Cardiovascular Disease Risk Among African American Women","volume":"36","author":"Bleil","year":"2017","journal-title":"Popul. Res. Policy Rev."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1093\/ije\/dyu071","article-title":"Child maltreatment and household dysfunction: Associations with pubertal development in a British birth cohort","volume":"43","author":"Li","year":"2014","journal-title":"Int. J. Epidemiol."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.anbehav.2008.12.014","article-title":"Male dominance rank and reproductive success in chimpanzees, Pan troglodytes schweinfurthii","volume":"77","author":"Wroblewski","year":"2009","journal-title":"Anim. Behav."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.yhbeh.2013.05.003","article-title":"Environmental and social influences on neuroendocrine puberty and behavior in macaques and other nonhuman primates","volume":"64","author":"Stephens","year":"2013","journal-title":"Horm. Behav."},{"key":"ref_91","doi-asserted-by":"crossref","unstructured":"Mushannen, T., Cortez, P., Stanford, F.C., and Singhal, V. (2019). Obesity and Hypogonadism-A Narrative Review Highlighting the Need for High-Quality Data in Adolescents. Children, 6.","DOI":"10.3390\/children6050063"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1097\/PSY.0000000000000430","article-title":"Measuring Childhood Adversity in Life Course Cardiovascular Research: A Systematic Review","volume":"79","author":"Appleton","year":"2017","journal-title":"Psychosom. Med."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1467-8624.2009.01263.x","article-title":"Pubertal development: Correspondence between hormonal and physical development","volume":"80","author":"Shirtcliff","year":"2009","journal-title":"Child Dev."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1210\/jc.2016-1073","article-title":"Pubertal Onset in Boys and Girls Is Influenced by Pubertal Timing of Both Parents","volume":"101","author":"Mouritsen","year":"2016","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S1054-139X(96)00087-0","article-title":"Ethnicity and body dissatisfaction: Are Hispanic and Asian girls at increased risk for eating disorders?","volume":"19","author":"Robinson","year":"1996","journal-title":"J. Adolesc. Health"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S1054-139X(98)00160-8","article-title":"Body image, perceived pubertal timing, and adolescent mental health","volume":"25","author":"Siegel","year":"1999","journal-title":"J. Adolesc. Health"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/pr.2015.129","article-title":"Predicting pubertal development by infantile and childhood height, BMI, and adiposity rebound","volume":"78","author":"German","year":"2015","journal-title":"Pediatr. Res."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.jadohealth.2011.10.006","article-title":"Contextual Amplification or Attenuation of Pubertal Timing Effects on Depressive Symptoms Among Mexican American Girls","volume":"50","author":"White","year":"2012","journal-title":"J. Adolesc. 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