{"status":"ok","message-type":"work-list","message-version":"1.0.0","message":{"facets":{},"total-results":90541,"items":[{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:39:29Z","timestamp":1760060369501,"version":"build-2065373602"},"reference-count":65,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T00:00:00Z","timestamp":1756166400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Languages"],"abstract":"<jats:p>Taking the domain of polar questions in Bosnian\/Croatian\/Montenegrin\/Serbian (BCMS) as the empirical background, the paper probes into the syntax\u2013phonology (CS-PF) interface and discusses insertion and movement as PF-repair strategies mitigating against the lack of convergence at PF. Contra previous accounts, the analysis treats li (lexicalization of Q) as a \u2018run-of-the-mill\u2019 2P clitic in BCMS, whose host cannot always be provided by syntax. I provide evidence against Prosodic Inversion\u2014\u2018the usual suspect\u2019 for post-syntactic movement in Slavic\u2014thus adding to the body of evidence that Prosodic Inversion does not take place in BCMS. I argue that the PF Movement in such cases has to be raising and adopt Local Dislocation to account for them. Probing into the interaction between Future I and polar questions provides further insights into the ordering of PF Movement operations in BCMS.<\/jats:p>","DOI":"10.3390\/languages10090210","type":"journal-article","created":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T14:18:49Z","timestamp":1756217929000},"page":"210","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mismatches and Mitigation at CS-PF Interface: The Curious Case of li"],"prefix":"10.3390","volume":"10","author":[{"given":"Marijana","family":"Marelj","sequence":"first","affiliation":[{"name":"Linguistics, Department of Languages, Literature, and Communication, Institute of Language Sciences, Faculty of Humanities, Utrecht University, 3512 JK Utrecht, The Netherlands"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.2307\/416416","article-title":"Wackernagel\u2019s revenge: Clitics, morphology, and the syntax of second position","volume":"69","author":"Anderson","year":"1993","journal-title":"Language"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Anderson, S. 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Although Detection Transformer (DETR)-based methods have made progress, they still face significant limitations in small object detection, primarily due to their reliance on global features, which fail to capture fine-grained details and are sensitive to background noise and bounding box variations. This study proposes Progressive Fusion (PF)-DETR, a model specifically designed to refine small object detection through progressive feature fusion techniques. Central to our approach is the Cross-Scale Feature Fusion with S2 (S2-CCFF) module, which integrates multi-level features with an S2 layer to preserve small object details. Coupled with SPace-to-Depth convolution (SPDConv) downsampling, this module reduces computational cost while maintaining critical information. Additionally, Cross Stage Partial Omni-Kernel Fusion (CSPOK-Fusion) Module achieves progressive fusion by gradually integrating multi-scale features from local, large, and global branches through successive convolutional layers, effectively refining the feature representation at each stage, mitigating background interference and occlusion effects to enhance cross-scale spatial representation. We further introduce a Parallelized Patch-Aware (PPA) attention module in the Backbone network to prioritize small object features, significantly addressing information loss. Finally, Normalized Wasserstein Distance (NWD) loss function is incorporated to heighten robustness against minor localization errors by aligning bounding box positioning and shape, thus boosting detection accuracy. 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We examined the relationship between fibrin D-dimer levels and the occurrence of complications in patients with sickle cell disease, using a commercially available latex bead agglutination assay. The patients were either asymptomatic, hospitalized for vaso-occlusive crisis, or had other complications of sickle cell disease including leg ulcers, chronic cholecystitis, aseptic necrosis, joint pain and infection. Fifty-seven percent of 187 samples on 96 patients had elevated levels of fibrin D-dimer. Ninety percent of 75 samples from asymptomatic patients were negative for fibrin D-dimer (less than 1 microgram\/ml) but 97% of 29 samples from patients with vaso-occlusive crisis and 85% of 83 samples from patients with other complications of sickle cell disease were positive. In serial studies, worsening or amelioration in clinical complications were reflected in increasing or decreasing levels of fibrin D-dimer, respectively. The molecular species of fibrin identified by the latex agglutination test was shown to be fragment D-dimer by successive immunoprecipitation and protein blot analysis. We conclude that the complications of sickle cell disease, including vaso-occlusive crisis, result in the production of fibrin D-dimer, and its detection may be used as a marker for the presence of the complication.<\/jats:p>","DOI":"10.1182\/blood.v68.1.317.bloodjournal681317","type":"journal-article","created":{"date-parts":[[2019,10,10]],"date-time":"2019-10-10T16:25:31Z","timestamp":1570724731000},"page":"317-319","update-policy":"http:\/\/dx.doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":2,"title":["Fragment D-dimer levels: an objective marker of vaso-occlusive crisis and other complications of sickle cell disease"],"prefix":"10.1182","volume":"68","author":[{"given":"DV","family":"Devine","sequence":"first","affiliation":[]},{"given":"TR","family":"Kinney","sequence":"additional","affiliation":[]},{"given":"PF","family":"Thomas","sequence":"additional","affiliation":[]},{"given":"WF","family":"Rosse","sequence":"additional","affiliation":[]},{"given":"CS","family":"Greenberg","sequence":"additional","affiliation":[]}],"member":"234","container-title":["Blood"],"language":"en","link":[{"URL":"http:\/\/ashpublications.org\/blood\/article-pdf\/68\/1\/317\/214041\/317.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/ashpublications.org\/blood\/article-pdf\/68\/1\/317\/214041\/317.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,16]],"date-time":"2019-11-16T00:21:25Z","timestamp":1573863685000},"score":16.370356,"resource":{"primary":{"URL":"https:\/\/ashpublications.org\/blood\/article\/68\/1\/317\/11085\/Fragment-Ddimer-levels-an-objective-marker-of"}},"issued":{"date-parts":[[1986,7,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1986,7,1]]}},"URL":"https:\/\/doi.org\/10.1182\/blood.v68.1.317.bloodjournal681317","ISSN":["0006-4971","1528-0020"],"issn-type":[{"value":"0006-4971","type":"print"},{"value":"1528-0020","type":"electronic"}],"published":{"date-parts":[[1986,7,1]]}},{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:08:53Z","timestamp":1770822533544,"version":"3.50.1"},"reference-count":0,"publisher":"American Society of Hematology","issue":"1","content-domain":{"domain":["ashpublications.org"],"crossmark-restriction":true},"published-print":{"date-parts":[[1986,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Although abnormalities in coagulation tests have been reported during vaso-occlusive crises in patients with sickle cell disease, objective, readily performed laboratory tests that document the occurrence of this complication have not been available. We examined the relationship between fibrin D-dimer levels and the occurrence of complications in patients with sickle cell disease, using a commercially available latex bead agglutination assay. The patients were either asymptomatic, hospitalized for vaso-occlusive crisis, or had other complications of sickle cell disease including leg ulcers, chronic cholecystitis, aseptic necrosis, joint pain and infection. Fifty-seven percent of 187 samples on 96 patients had elevated levels of fibrin D-dimer. Ninety percent of 75 samples from asymptomatic patients were negative for fibrin D-dimer (less than 1 microgram\/ml) but 97% of 29 samples from patients with vaso-occlusive crisis and 85% of 83 samples from patients with other complications of sickle cell disease were positive. In serial studies, worsening or amelioration in clinical complications were reflected in increasing or decreasing levels of fibrin D-dimer, respectively. The molecular species of fibrin identified by the latex agglutination test was shown to be fragment D-dimer by successive immunoprecipitation and protein blot analysis. We conclude that the complications of sickle cell disease, including vaso-occlusive crisis, result in the production of fibrin D-dimer, and its detection may be used as a marker for the presence of the complication.<\/jats:p>","DOI":"10.1182\/blood.v68.1.317.317","type":"journal-article","created":{"date-parts":[[2019,10,13]],"date-time":"2019-10-13T11:57:47Z","timestamp":1570967867000},"page":"317-319","update-policy":"https:\/\/doi.org\/10.1182\/blood.2019cm0000","source":"Crossref","is-referenced-by-count":48,"title":["Fragment D-dimer levels: an objective marker of vaso-occlusive crisis and other complications of sickle cell disease"],"prefix":"10.1182","volume":"68","author":[{"given":"DV","family":"Devine","sequence":"first","affiliation":[]},{"given":"TR","family":"Kinney","sequence":"additional","affiliation":[]},{"given":"PF","family":"Thomas","sequence":"additional","affiliation":[]},{"given":"WF","family":"Rosse","sequence":"additional","affiliation":[]},{"given":"CS","family":"Greenberg","sequence":"additional","affiliation":[]}],"member":"234","container-title":["Blood"],"language":"en","link":[{"URL":"http:\/\/ashpublications.org\/blood\/article-pdf\/68\/1\/317\/595266\/317.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/ashpublications.org\/blood\/article-pdf\/68\/1\/317\/595266\/317.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T02:08:05Z","timestamp":1574215685000},"score":16.268799,"resource":{"primary":{"URL":"https:\/\/ashpublications.org\/blood\/article\/68\/1\/317\/165154\/Fragment-Ddimer-levels-an-objective-marker-of"}},"issued":{"date-parts":[[1986,7,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1986,7,1]]}},"URL":"https:\/\/doi.org\/10.1182\/blood.v68.1.317.317","ISSN":["0006-4971","1528-0020"],"issn-type":[{"value":"0006-4971","type":"print"},{"value":"1528-0020","type":"electronic"}],"published":{"date-parts":[[1986,7,1]]}},{"indexed":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T19:40:11Z","timestamp":1740685211688,"version":"3.38.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1995,11,1]],"date-time":"1995-11-01T00:00:00Z","timestamp":815184000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mult Scler"],"published-print":{"date-parts":[[1995,11]]},"abstract":"<jats:p> We report the occurrence of clinically definite multiple sclerosis in an offspring of a couple with conjugal multiple sclerosis. Extensive investigation of all members of this family, which includes two additional asymptomatic children, eliminated the possibility of alternative neurological diagnoses. All family members were studied with magnetic resonance imaging (MRI), evoked potentials, and human leukocyte antigen (HLA) typing. An asymptomatic child had subtle white matter abnormalities on MRI, suggesting subclinical neurological involvement This study documents the third case of multiple sclerosis in the child of conjugal multiple sclerosis patients and provides the first report of MRI lesions in an asymptomatic offspring of the same parents. Neurodiagnostic and immunogenetic investigations of such rare family clusters may contribute to the elucidation of the pathogenesis of multiple sclerosis. <\/jats:p>","DOI":"10.1177\/135245859500100307","type":"journal-article","created":{"date-parts":[[2017,7,6]],"date-time":"2017-07-06T07:36:48Z","timestamp":1499326608000},"page":"170-172","source":"Crossref","is-referenced-by-count":4,"title":["Clinical and subclinical neurological involvement in children of conjugal multiple sclerosis patients"],"prefix":"10.1177","volume":"1","author":[{"given":"CS","family":"Constantinescu","sequence":"first","affiliation":[{"name":"Departments of Neurology"}]},{"given":"RI","family":"Grossman","sequence":"additional","affiliation":[{"name":"Departments of Radiology"}]},{"given":"PF","family":"Finelli","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hartford Hospital, Hartford, CT"}]},{"given":"M","family":"Kamoun","sequence":"additional","affiliation":[{"name":"Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA"}]},{"given":"C","family":"Zmijewski","sequence":"additional","affiliation":[{"name":"Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA"}]},{"given":"JA","family":"Cohen","sequence":"additional","affiliation":[{"name":"Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic Foundation, Cleveland, OH, USA"}]}],"member":"179","published-online":{"date-parts":[[1995,11,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(66)90012-8"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.5.727"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198612253152603"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.8.1320-a"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.3.577"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.21.11.1169"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1983.04050080033003"},{"key":"atypb8","first-page":"581","volume":"9","author":"Girones L","year":"1928","journal-title":"Rev Med Barcelona"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.8.1644-b"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.6.900"},{"key":"atypb11","first-page":"3","volume-title":"McAlpine's Multiple Sclerosis.","author":"Martyn CN","year":"1991"},{"key":"atypb12","first-page":"137","volume":"35","author":"McFarland HF","year":"1985","journal-title":"Neurology"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.18.7113"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.46.5.414"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.6.990"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320290310"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100030936"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410330309"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410360806"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/86.2.315"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-193807000-00005"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.55.10.883"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.9.1354"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.6.769"}],"container-title":["Multiple Sclerosis Journal"],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/135245859500100307","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/135245859500100307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T19:09:54Z","timestamp":1740683394000},"score":16.153435,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/135245859500100307"}},"issued":{"date-parts":[[1995,11]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,11]]}},"alternative-id":["10.1177\/135245859500100307"],"URL":"https:\/\/doi.org\/10.1177\/135245859500100307","ISSN":["1352-4585","1477-0970"],"issn-type":[{"type":"print","value":"1352-4585"},{"type":"electronic","value":"1477-0970"}],"published":{"date-parts":[[1995,11]]}},{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T22:06:15Z","timestamp":1648850775621},"reference-count":0,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"15_suppl","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCO"],"published-print":{"date-parts":[[2012,5,20]]},"abstract":"<jats:p> 6085 <\/jats:p><jats:p> Background: The longevity of CS is increasing, underscoring the importance of lifestyle modifications and preventive care, consisting of regular PA and maintenance of PF. Our aims were to 1) compare PA and PF among short-term CS, long-term CS and non-cancer controls (NCC) and 2) identify other clinical factors associated with decreased PA and PF. Methods: We identified CS and NCC from the US National Health and Nutrition Examination Survey (NHANES). CS were categorized into &lt;\/=5 (short-term) and &gt;5 years (long-term) based on date of diagnosis. Multivariate weighted regression models were constructed to examine for differences in 28 and 26 measures of PA and PF, respectively, while controlling for age, gender, ethnicity, education, income, and other confounders. We explored specific and general PA domains such as aerobic activity and decline from past activity level as well as PF areas including ADLs, IADLs and mobility. Results: In total, 26,185 subjects were identified: 968 short-term CS, 1,367 long-term CS, and 23,832 NCC. For the entire cohort, the mean age was 50 years, 52% were men, and 50% were white. Comparing across the 3 patient groups, CS were generally older than NCC (60 vs 45 years, p&lt;0.01). In terms of PA, short-term CS reported less general activity compared to 1 year ago (OR 0.58, 95%, CI 0.46-0.73, p&lt;0.01) than long-term CS and NCC. In comparison to NCC, both groups of CS also described less current activity than their baseline from 10 years ago (OR 0.63, 95% CI 0.48-0.82, P=0.001 and OR 0.67, 95% CI 0.55-0.83, P=&lt;0.01). There were significant differences among patient groups in several areas of PF (Table). Other factors that were associated with lower PA and PF included advanced age, low education, and low income. Conclusions: PA between CS and NCC were similar, although current activity as compared to that of the preceding year or past decade appears lower in CS, which may reflect their older age. Impairments in several measures of PF were observed among CS, which could impact their quality and quantity of life. [Table: see text] <\/jats:p>","DOI":"10.1200\/jco.2012.30.15_suppl.6085","type":"journal-article","created":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T15:18:18Z","timestamp":1583939898000},"page":"6085-6085","source":"Crossref","is-referenced-by-count":0,"title":["Physical activity (PA) and physical function (PF) in adult cancer survivors (CS)."],"prefix":"10.1200","volume":"30","author":[{"given":"Peter Crawford","family":"Birks","sequence":"first","affiliation":[{"name":"British Columbia Cancer Agency, Vancouver, BC, Canada"}]},{"given":"Amir Yashar","family":"Tashakkor","sequence":"additional","affiliation":[{"name":"British Columbia Cancer Agency, Vancouver, BC, Canada"}]},{"given":"Ali","family":"Moghaddamjou","sequence":"additional","affiliation":[{"name":"British Columbia Cancer Agency, Vancouver, BC, Canada"}]},{"given":"Winson Y.","family":"Cheung","sequence":"additional","affiliation":[{"name":"British Columbia Cancer Agency, Vancouver, BC, 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Supercond."},{"issue":"1","key":"10.1016\/j.fusengdes.2021.112836_bib0020","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1109\/77.828413","article-title":"A Practical Fit for the Critical Surface of NbTi","volume":"10","author":"Bottura","year":"2000","journal-title":"IEEE Trans. Appl. Supercond."},{"key":"10.1016\/j.fusengdes.2021.112836_bib0021","unstructured":"N. Pompeo and L. Muzzi, \u201cThe superconducting proposal for the CS magnet system of FAST: a preliminary analysis of the heat load due to AC losses\u201d, arXiv, 1101.5825, 2011."},{"key":"10.1016\/j.fusengdes.2021.112836_bib0022","series-title":"presented at DTT Design Review Meeting 03","article-title":"Thermal Shield","author":"Barone","year":"2019"},{"key":"10.1016\/j.fusengdes.2021.112836_bib0023","series-title":"presented at DTT Design Review Meeting 03","article-title":"Nuclear loads for SC magnets design","author":"Villari","year":"2019"}],"container-title":["Fusion Engineering and Design"],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920379621006128?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920379621006128?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T14:09:17Z","timestamp":1760278157000},"score":15.806622,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920379621006128"}},"issued":{"date-parts":[[2021,12]]},"references-count":23,"alternative-id":["S0920379621006128"],"URL":"https:\/\/doi.org\/10.1016\/j.fusengdes.2021.112836","ISSN":["0920-3796"],"issn-type":[{"value":"0920-3796","type":"print"}],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Thermal-hydraulic analysis of the DTT CS and PF pulsed coil performance during AC operation","name":"articletitle","label":"Article Title"},{"value":"Fusion Engineering and Design","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fusengdes.2021.112836","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112836"},{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:32:35Z","timestamp":1760232755865,"version":"build-2065373602"},"reference-count":41,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T00:00:00Z","timestamp":1669766400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001288","name":"Parkinson\u2019s Foundation","doi-asserted-by":"publisher","award":["PF-FBS-1898","PF-CRA-2073"],"award-info":[{"award-number":["PF-FBS-1898","PF-CRA-2073"]}],"id":[{"id":"10.13039\/100001288","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001288","name":"Parkinson\u2019s Foundation","doi-asserted-by":"publisher","award":["PF-FBS-1898","PF-CRA-2073"],"award-info":[{"award-number":["PF-FBS-1898","PF-CRA-2073"]}],"id":[{"id":"10.13039\/100001288","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Northumbria University PhD studentship","award":["PF-FBS-1898","PF-CRA-2073"],"award-info":[{"award-number":["PF-FBS-1898","PF-CRA-2073"]}]},{"name":"Private Physiotherapy Educational Foundation","award":["PF-FBS-1898","PF-CRA-2073"],"award-info":[{"award-number":["PF-FBS-1898","PF-CRA-2073"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Background: Turning is a complex measure of gait that accounts for over 50% of daily steps. Traditionally, turning has been measured in a research grade laboratory setting, however, there is demand for a low-cost and portable solution to measure turning using wearable technology. This study aimed to determine the suitability of a low-cost inertial sensor-based device (AX6, Axivity) to assess turning, by simultaneously capturing and comparing to a turn algorithm output from a previously validated reference inertial sensor-based device (Opal), in healthy young adults. Methodology: Thirty participants (aged 23.9 \u00b1 4.89 years) completed the following turning protocol wearing the AX6 and reference device: a turn course, a two-minute walk (including 180\u00b0 turns) and turning in place, alternating 360\u00b0 turn right and left. Both devices were attached at the lumbar spine, one Opal via a belt, and the AX6 via double sided tape attached directly to the skin. Turning measures included number of turns, average turn duration, angle, velocity, and jerk. Results: Agreement between the outcomes from the AX6 and reference device was good to excellent for all turn characteristics (all ICCs &gt; 0.850) during the turning 360\u00b0 task. There was good agreement for all turn characteristics (all ICCs &gt; 0.800) during the two-minute walk task, except for moderate agreement for turn angle (ICC 0.683). Agreement for turn outcomes was moderate to good during the turns course (ICCs range; 0.580 to 0.870). Conclusions: A low-cost wearable sensor, AX6, can be a suitable and fit-for-purpose device when used with validated algorithms for assessment of turning outcomes, particularly during continuous turning tasks. Future work needs to determine the suitability and validity of turning in aging and clinical cohorts within low-resource settings.<\/jats:p>","DOI":"10.3390\/s22239322","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T08:46:41Z","timestamp":1669798001000},"page":"9322","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Suitability of a Low-Cost Wearable Sensor to Assess Turning in Healthy Adults"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5087-1969","authenticated-orcid":false,"given":"Rachel","family":"Mason","sequence":"first","affiliation":[{"name":"Department Sport, Exercise and Rehabilitation, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"given":"Joe","family":"Byerley","sequence":"additional","affiliation":[{"name":"Department Sport, Exercise and Rehabilitation, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"given":"Andrea","family":"Baker","sequence":"additional","affiliation":[{"name":"Department Sport, Exercise and Rehabilitation, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1233-5468","authenticated-orcid":false,"given":"Dylan","family":"Powell","sequence":"additional","affiliation":[{"name":"Department Computer Science, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8011-8601","authenticated-orcid":false,"given":"Liam T.","family":"Pearson","sequence":"additional","affiliation":[{"name":"Department Sport, Exercise and Rehabilitation, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"given":"Gill","family":"Barry","sequence":"additional","affiliation":[{"name":"Department Sport, Exercise and Rehabilitation, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4049-9291","authenticated-orcid":false,"given":"Alan","family":"Godfrey","sequence":"additional","affiliation":[{"name":"Department Computer Science, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"given":"Martina","family":"Mancini","sequence":"additional","affiliation":[{"name":"Department of Neurology, Oregon Health and Science University, Portland, OR 97239-3098, USA"}]},{"given":"Samuel","family":"Stuart","sequence":"additional","affiliation":[{"name":"Department Sport, Exercise and Rehabilitation, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"},{"name":"Northumbria Healthcare NHS Foundation Trust, North Shields NE29 8NH, UK"}]},{"given":"Rosie","family":"Morris","sequence":"additional","affiliation":[{"name":"Department Sport, Exercise and Rehabilitation, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"},{"name":"Northumbria Healthcare NHS Foundation Trust, North Shields NE29 8NH, UK"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.gaitpost.2006.04.003","article-title":"Video task analysis of turning during activities of daily living","volume":"25","author":"Glaister","year":"2007","journal-title":"Gait Posture"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1089\/neu.2019.6450","article-title":"Analysis of Free-Living Mobility in People with Mild Traumatic Brain Injury and Healthy Controls: Quality over Quantity","volume":"37","author":"Stuart","year":"2020","journal-title":"J. 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Sci."}],"container-title":["Sensors"],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/22\/23\/9322\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:30:03Z","timestamp":1760146203000},"score":15.72457,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/22\/23\/9322"}},"issued":{"date-parts":[[2022,11,30]]},"references-count":41,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["s22239322"],"URL":"https:\/\/doi.org\/10.3390\/s22239322","ISSN":["1424-8220"],"issn-type":[{"type":"electronic","value":"1424-8220"}],"published":{"date-parts":[[2022,11,30]]}},{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T12:11:59Z","timestamp":1648987919473},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Planta Med"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1055\/s-0032-1321050","type":"journal-article","created":{"date-parts":[[2012,8,30]],"date-time":"2012-08-30T09:04:01Z","timestamp":1346317441000},"source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the schistosomicidal activity of nor-neolignans from Styrax pohlii"],"prefix":"10.1055","volume":"78","author":[{"given":"E","family":"Soares","sequence":"first","affiliation":[]},{"given":"CS","family":"Bertanha","sequence":"additional","affiliation":[]},{"given":"PF","family":"de Oliveira","sequence":"additional","affiliation":[]},{"given":"UO","family":"Gon\u00e7alves","sequence":"additional","affiliation":[]},{"given":"LG","family":"Magalh\u00e3es","sequence":"additional","affiliation":[]},{"given":"V","family":"Rodrigues","sequence":"additional","affiliation":[]},{"given":"MLA","family":"Silva","sequence":"additional","affiliation":[]},{"given":"DC","family":"Tavares","sequence":"additional","affiliation":[]},{"given":"AH","family":"Janu\u00e1rio","sequence":"additional","affiliation":[]},{"given":"PM","family":"Pauletti","sequence":"additional","affiliation":[]}],"member":"194","published-online":{"date-parts":[[2012,7,19]]},"container-title":["Planta Medica"],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0032-1321050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,22]],"date-time":"2017-05-22T18:05:18Z","timestamp":1495476318000},"score":15.527099,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0032-1321050"}},"issued":{"date-parts":[[2012,7]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0032-1321050","ISSN":["0032-0943","1439-0221"],"issn-type":[{"value":"0032-0943","type":"print"},{"value":"1439-0221","type":"electronic"}],"published":{"date-parts":[[2012,7]]}},{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T16:48:12Z","timestamp":1765039692802,"version":"build-2065373602"},"reference-count":190,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T00:00:00Z","timestamp":1681862400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Regional Development Intensive Industrial Innovation Programme","award":["25R17P01847","PF-FBS-1898","PF-CRA-2073"],"award-info":[{"award-number":["25R17P01847","PF-FBS-1898","PF-CRA-2073"]}]},{"name":"Northumbria University","award":["25R17P01847","PF-FBS-1898","PF-CRA-2073"],"award-info":[{"award-number":["25R17P01847","PF-FBS-1898","PF-CRA-2073"]}]},{"name":"Parkinson\u2019s Foundation","award":["25R17P01847","PF-FBS-1898","PF-CRA-2073"],"award-info":[{"award-number":["25R17P01847","PF-FBS-1898","PF-CRA-2073"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Walking\/gait quality is a useful clinical tool to assess general health and is now broadly described as the sixth vital sign. This has been mediated by advances in sensing technology, including instrumented walkways and three-dimensional motion capture. However, it is wearable technology innovation that has spawned the highest growth in instrumented gait assessment due to the capabilities for monitoring within and beyond the laboratory. Specifically, instrumented gait assessment with wearable inertial measurement units (IMUs) has provided more readily deployable devices for use in any environment. Contemporary IMU-based gait assessment research has shown evidence of the robust quantifying of important clinical gait outcomes in, e.g., neurological disorders to gather more insightful habitual data in the home and community, given the relatively low cost and portability of IMUs. The aim of this narrative review is to describe the ongoing research regarding the need to move gait assessment out of bespoke settings into habitual environments and to consider the shortcomings and inefficiencies that are common within the field. Accordingly, we broadly explore how the Internet of Things (IoT) could better enable routine gait assessment beyond bespoke settings. As IMU-based wearables and algorithms mature in their corroboration with alternate technologies, such as computer vision, edge computing, and pose estimation, the role of IoT communication will enable new opportunities for remote gait assessment.<\/jats:p>","DOI":"10.3390\/s23084100","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T02:01:11Z","timestamp":1681956071000},"page":"4100","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["IoT-Enabled Gait Assessment: The Next Step for Habitual Monitoring"],"prefix":"10.3390","volume":"23","author":[{"given":"Fraser","family":"Young","sequence":"first","affiliation":[{"name":"Department of Computer and Information Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5087-1969","authenticated-orcid":false,"given":"Rachel","family":"Mason","sequence":"additional","affiliation":[{"name":"Department of Health and Life Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"given":"Rosie E.","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Health and Life Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"given":"Samuel","family":"Stuart","sequence":"additional","affiliation":[{"name":"Department of Health and Life Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4049-9291","authenticated-orcid":false,"given":"Alan","family":"Godfrey","sequence":"additional","affiliation":[{"name":"Department of Computer and Information Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Friedl, K.E., and Looney, D.P. 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systems and toothbrush abrasion on transmittance (T) and surface roughness (Ra) of three composite resins (Filtek Z350 XT, Tetric N-Ceram, and IPS Empress Direct). Eighteen resin disks (10 mm diameter \u00d7 2 mm thick) finished by polyester strips had initial surface smoothness recorded, representing phase 1 (P1). Specimens were divided into three groups (n=6) according to the finishing\/polishing instrument used (OneGloss, TopGloss, and Sof-Lex) to compose phase 2 samples (P2). Then specimens were subjected to 514 cycles of toothbrush simulation using a toothpaste slurry, with a constant load applied to soft bristles, and were then washed (phase 3=P3). After each phase, the specimens were examined by an optical profiler and spectrophotometer to measure Ra and T. Data were analyzed by analysis of variance, Tukey and Pearson tests. T values were statistically influenced by composite resin (\u200ap=0.000) and phase of measurement (\u200ap=0.000) factors, while the finishing\/polishing system used (\u200ap=0.741) did not affect T. On the other hand, Ra values were statistically affected by the factor finishing\/polishing system (\u200ap=0.000), but not by composite resin (\u200ap=0.100) and phase of measurement (\u200ap=0.451). Tetric N-Ceram and Empress Direct presented higher values of roughness when polished by OneGloss, while TopGloss and Sof-Lex showed a lower roughness. It can be concluded that composite resins transmitted more light after dental abrasion. Transmittance of composite resins was not modified by the distinct roughness created by finishing\/polishing instruments.<\/jats:p>","DOI":"10.2341\/15-281-l","type":"journal-article","created":{"date-parts":[[2016,11,7]],"date-time":"2016-11-07T16:38:53Z","timestamp":1478536733000},"page":"634-641","source":"Crossref","is-referenced-by-count":8,"title":["Influence of Finishing and Polishing Techniques and Abrasion on Transmittance and Roughness of Composite Resins"],"prefix":"10.2341","volume":"41","author":[{"given":"PMA","family":"Carneiro","sequence":"first","affiliation":[{"name":"Paula Mendes Acatauass\u00fa Carneiro, DDS, MSc, University of Sao Paulo\u2013School of Dentistry, Operative Dentistry Department, Sao Paulo, Brazil"}]},{"given":"TM","family":"Ramos","sequence":"first","affiliation":[{"name":"Thayanne Monteiro Ramos-Oliveira, DDS, MSc, PhD, University of Sao Paulo\u2013School of Dentistry, Operative Dentistry Department, Sao Paulo, Brazil"}]},{"given":"CS","family":"de 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Foundation","doi-asserted-by":"publisher","award":["PF-CRA-2073"],"award-info":[{"award-number":["PF-CRA-2073"]}],"id":[{"id":"10.13039\/100001262","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Running gait assessment is essential for the development of technical optimization strategies as well as to inform injury prevention and rehabilitation. Currently, running gait assessment relies on (i) visual assessment, exhibiting subjectivity and limited reliability, or (ii) use of instrumented approaches, which often carry high costs and can be intrusive due to the attachment of equipment to the body. Here, the use of an IoT-enabled markerless computer vision smartphone application based upon Google\u2019s pose estimation model BlazePose was evaluated for running gait assessment for use in low-resource settings. That human pose estimation architecture was used to extract contact time, swing time, step time, knee flexion angle, and foot strike location from a large cohort of runners. The gold-standard Vicon 3D motion capture system was used as a reference. The proposed approach performs robustly, demonstrating good (ICC(2,1) &gt; 0.75) to excellent (ICC(2,1) &gt; 0.90) agreement in all running gait outcomes. Additionally, temporal outcomes exhibit low mean error (0.01\u20130.014 s) in left foot outcomes. However, there are some discrepancies in right foot outcomes, due to occlusion. This study demonstrates that the proposed low-cost and markerless system provides accurate running gait assessment outcomes. The approach may help routine running gait assessment in low-resource environments.<\/jats:p>","DOI":"10.3390\/s23020696","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T07:05:09Z","timestamp":1673247909000},"page":"696","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Internet-of-Things-Enabled Markerless Running Gait Assessment from a Single Smartphone Camera"],"prefix":"10.3390","volume":"23","author":[{"given":"Fraser","family":"Young","sequence":"first","affiliation":[{"name":"Department of Computer and Information Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5087-1969","authenticated-orcid":false,"given":"Rachel","family":"Mason","sequence":"additional","affiliation":[{"name":"Department of Health and Life Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"given":"Rosie","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Health and Life Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"given":"Samuel","family":"Stuart","sequence":"additional","affiliation":[{"name":"Department of Health and Life Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4049-9291","authenticated-orcid":false,"given":"Alan","family":"Godfrey","sequence":"additional","affiliation":[{"name":"Department of Computer and Information Sciences, Northumbria University, Newcastle-upon-Tyne NE1 8ST, UK"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1177\/1757913910379191","article-title":"Running free: Embracing a healthy lifestyle through distance running","volume":"130","author":"Shipway","year":"2010","journal-title":"Perspect. 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