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Geochimica et Cosmochimica Acta, 44, 1311\u20131317.","journal-title":"Geochimica et Cosmochimica Acta"}],"container-title":["Geosciences Journal"],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12303-018-0002-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12303-018-0002-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12303-018-0002-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,24]],"date-time":"2019-02-24T01:21:03Z","timestamp":1550971263000},"score":16.34666,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12303-018-0002-7"}},"issued":{"date-parts":[[2018,2,24]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["2"],"URL":"https:\/\/doi.org\/10.1007\/s12303-018-0002-7","ISSN":["1226-4806","1598-7477"],"issn-type":[{"value":"1226-4806","type":"print"},{"value":"1598-7477","type":"electronic"}],"published":{"date-parts":[[2018,2,24]]},"assertion":[{"value":"9 October 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 January 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]},{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T01:58:14Z","timestamp":1761789494711},"reference-count":0,"publisher":"Bangladesh Journals Online (JOL)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J bio-sci."],"abstract":"<jats:p>In the early stage of drug development process, it is urgent to judge the toxicity effect of some common chemical compounds (CCs) that is not yet well investigated. Biomarker genes (BGs) and dose of CCs can help to draw a deduction about a drug for safety assessment. Classical toxicology method uses large number of samples to extract clinical results which is both time consuming and costly. However, conventional molecular methods can perform to identify only BGs and fail to detect source factor influencing these BGs. The aim of this study is to propose a suitable algorithm that can identify more promising and essential toxicity biomarkers related to some common CCs for safety assessment of new drugs. The glutathione is an effective metabolite of detoxification process in liver. Glutathione depletion analysis is one of the major key research areas in drug development pipeline. In this paper, we studied glutathione depletion analysis of some reported CCs (acetaminophen, methapyrilene and nitrofurazone). We develop an algorithm combining ANOVA and principal component analysis (PCA) using visualization technique to find biomarker genes and associated glutathione depleting CCs and their corresponding doses. There are numerous numbers of genes in the glutathione metabolism pathway regulated as differentially expressed (DE) genes due to the toxic effect of these CCs and proposed algorithm identify only five genes (Mgst2, Gclc, G6pd, Gsr and Srm) that are also foremost genes in the glutathione metabolism pathway. Proposed algorithm states that high dose of all the CCs are responsible for glutathione depletion, nevertheless middle dose of acetaminophen and nitrofurazone also cause glutathione depletion. The proposed algorithm has an additional benefit over the conventional method to discover new chemical entities toxicity.J. bio-sci. 25: 57-66, 2017<\/jats:p>","DOI":"10.3329\/jbs.v25i0.37499","type":"journal-article","created":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T16:38:50Z","timestamp":1531931930000},"page":"57-66","source":"Crossref","is-referenced-by-count":1,"title":["A novel computational approach for toxicogenomics biomarker discovery in drug development pipeline"],"prefix":"10.3329","volume":"25","author":[{"given":"MM","family":"Rana","sequence":"first","affiliation":[]},{"given":"MN","family":"Hasan","sequence":"first","affiliation":[]},{"given":"MS","family":"Ahmed","sequence":"first","affiliation":[]},{"given":"MNH","family":"Mollah","sequence":"first","affiliation":[]}],"member":"1861","published-online":{"date-parts":[[2018,7,18]]},"container-title":["Journal of Bio-Science"],"link":[{"URL":"https:\/\/www.banglajol.info\/index.php\/JBS\/article\/download\/37499\/25412","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.banglajol.info\/index.php\/JBS\/article\/download\/37499\/25412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,7]],"date-time":"2019-01-07T12:59:09Z","timestamp":1546865949000},"score":16.223478,"resource":{"primary":{"URL":"https:\/\/www.banglajol.info\/index.php\/JBS\/article\/view\/37499"}},"issued":{"date-parts":[[2018,7,18]]},"references-count":0,"URL":"https:\/\/doi.org\/10.3329\/jbs.v25i0.37499","ISSN":["2408-8595","1023-8654"],"issn-type":[{"value":"2408-8595","type":"electronic"},{"value":"1023-8654","type":"print"}],"published":{"date-parts":[[2018,7,18]]}},{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T12:33:39Z","timestamp":1761395619246,"version":"3.41.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Bio-Medical Materials and Engineering"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p>\n            Fibrinogen is a plasma glycoprotein that is an established cardiovascular risk and it participates in the blood-clotting mechanism. Nitrated fibrinogen has been shown to inhibit platelet aggregation and thrombus formation. However, there are only a few reports relating to the activity and structural changes of nitrified fibrinogen when metal ions are present in the reaction. Mn (II) ion plays an important physiological role in the nervous system and cardiac function. In this study, we use UV-Vis, 3D-fluorescence, SDS-PAGE electrophoresis and Von-Clauss to detect 3-nitrotyrosine (3-NT) production and the activity changes of fibrinogen after nitration and oxidation damage caused by ONOO\n            <jats:sup>\u2212<\/jats:sup>\n            in the presence of Mn (II). Results showed that Mn (II) can enhance the production of 3-NT in fibrinogen, promote fluorescence quenching of fibrinogen, and increase the injury to \u03b3 and A\u03b1 chains of fibrinogen in the presence of peroxynitrite. Consequently, Mn (II) promotes concentration dependent fibrinogen nitrification damage and significantly reduces the biological activity of nitrified fibrinogen.\n          <\/jats:p>","DOI":"10.3233\/bme-130884","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T19:40:40Z","timestamp":1575315640000},"page":"901-907","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Effects of Mn (II) on peroxynitrite nitrifying fibrinogen"],"prefix":"10.1177","volume":"24","author":[{"given":"Yang","family":"Ding","sequence":"first","affiliation":[{"name":"College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, P.R. China"}]},{"given":"Yunjing","family":"Luo","sequence":"additional","affiliation":[{"name":"College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, P.R. China"}]},{"given":"Jun","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Cadre Ward, First Hospital, Jilin University, Changchun130021, P.R. 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Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101018"},{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T13:47:48Z","timestamp":1771940868588,"version":"3.50.1"},"reference-count":22,"publisher":"EDP Sciences","license":[{"start":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T00:00:00Z","timestamp":1705017600000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BIO Web Conf."],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:p>Dyes are hazardous chemicals that are commonly found in textile industries\u2019 effluent water. Adsorption techniques are more efficiently used for the removal of various dyes from wastewater. The present work deals with the synthesis of Mn-Zn (Mn0.3Zn0.7Fe2O4) spinel ferrite through the solution combustion method. The solution combustion method has many advantages over other conventional methods. Single-phase spinel ferrite materials can be synthesized by using this method at lower temperatures and in a shorter time. Synthesized Mn-Zn spinel ferrite material has been characterized by using FT-IR spectroscopy. As synthesized ferrite material has been employed for the adsorption of various dyes with different concentrations from their aqueous solutions. Results related to dyes\u2019 adsorption have been reported using UV-Visible spectroscopy. Mn- Zn spinel ferrite has worked efficiently as an adsorbent and its magnetic nature is useful for its extraction from the aqueous solution.<\/jats:p>","DOI":"10.1051\/bioconf\/20248601004","type":"journal-article","created":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T13:33:15Z","timestamp":1705584795000},"page":"01004","source":"Crossref","is-referenced-by-count":3,"title":["Mn-Zn spinel ferrite synthesis by solution combustion method and applications in adsorption of dyes"],"prefix":"10.1051","volume":"86","author":[{"given":"I.","family":"Beri","sequence":"first","affiliation":[]},{"given":"M.","family":"Ayoub","sequence":"additional","affiliation":[]},{"given":"N.","family":"Fatma","sequence":"additional","affiliation":[]},{"given":"H.S.","family":"Dosanjh","sequence":"additional","affiliation":[]}],"member":"250","published-online":{"date-parts":[[2024,1,12]]},"reference":[{"key":"R1","first-page":"012086","volume":"2267","author":"Kant","year":"2022","journal-title":"J. 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Agarwood is considered as the most prized non-timber forest product (NTFP) used in attars as well as medicines. Quality of agarwood is the determiner for defining its commercial value. Different countries use different grading system to explain the quality of agarwood. In Bangladesh, more than 45 compounds have been identified so far, mostly sesquiterpenoids, alkanes, fatty acid and other volatile aromatic compounds that are responsible for its fragrance and high prices. Ether extract, total phenolic contents, flavonoid, antioxidant and microbiological tests have shown tremendous positive results. Chemical profiling of agar products is the best identified using GC-MS technique by the various authors. Present review discusses the full scenario of Aquilaria production, inoculation, extraction methods, determination of agarwood quality and chemical constituents of agar oils and possibilities and barriers of this industry in Bangladesh.\nJ. Bio-Sci. 29(2): 151-173, 2021 (December)<\/jats:p>","DOI":"10.3329\/jbs.v29i2.54963","type":"journal-article","created":{"date-parts":[[2021,8,4]],"date-time":"2021-08-04T17:08:47Z","timestamp":1628096927000},"page":"151-173","source":"Crossref","is-referenced-by-count":2,"title":["Inclusive Scenario of Natural Products Obtained From Agar Plant (Aquilaria SP.) In Bangladesh- A Review"],"prefix":"10.3329","volume":"29","author":[{"given":"MN","family":"Hoque","sequence":"first","affiliation":[]},{"given":"MF","family":"Mondal","sequence":"additional","affiliation":[]},{"given":"GHM","family":"Sagor","sequence":"additional","affiliation":[]},{"given":"MM","family":"Hasan","sequence":"additional","affiliation":[]},{"given":"A","family":"Hannan","sequence":"additional","affiliation":[]}],"member":"1861","published-online":{"date-parts":[[2021,8,4]]},"container-title":["Journal of Bio-Science"],"link":[{"URL":"https:\/\/www.banglajol.info\/index.php\/JBS\/article\/download\/54963\/38643","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.banglajol.info\/index.php\/JBS\/article\/download\/54963\/38643","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,4]],"date-time":"2021-08-04T17:08:49Z","timestamp":1628096929000},"score":15.5656395,"resource":{"primary":{"URL":"https:\/\/www.banglajol.info\/index.php\/JBS\/article\/view\/54963"}},"issued":{"date-parts":[[2021,8,4]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,8,4]]}},"URL":"https:\/\/doi.org\/10.3329\/jbs.v29i2.54963","ISSN":["2408-8595","1023-8654"],"issn-type":[{"value":"2408-8595","type":"electronic"},{"value":"1023-8654","type":"print"}],"published":{"date-parts":[[2021,8,4]]}},{"indexed":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T06:24:00Z","timestamp":1743575040753},"reference-count":20,"publisher":"EDP Sciences","license":[{"start":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:00:00Z","timestamp":1697414400000},"content-version":"vor","delay-in-days":288,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BIO Web Conf."],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>One of the coal mining corporations is in charge of environmental management, which includes managing water resources One of the coal mining corporations is in charge of environmental management, which includes managing water resources. The management of coal mine water that has the potential to become polluted water can be processed into fresh water in a sustainable manner. This indicates that acidic water from coal mines is still handled as waste that must be addressed once more. According Ministry of Health Regulation No. 416 1990 on Water Quality Requirements and Monitoring (Indonesian Government Regulation Ministry of Health related to water quality requirements and water quality monitoring), the purpose of this study is to evaluate the viability of coal mine acidic water quality in comparison to Fe (iron), Mn (manganese) ions, and pH parameters as fresh water. According to the findings of this study into acid mine drainage, the pH of the water in nine study areas in Pucok Reudeup Village, a former coal mining region, is low. The findings of this study on acid mine drainage demonstrate that the pH of the water at nine research sites in Pucok Reudeup a village near a disused coal mine. In nine research locations in Pucok Reudeup Village, a former coal mining area, the pH of the water did not exceed the established freshwater quality requirements (pH water below 6.5 - 9), according to the findings of this acid mine drainage study. Fe parameters that fulfilled the quality requirements were only present at five research sites. High iron concentrations result from Fe 2+ or Fe 3+ ions that cannot obtain oxygen from the environment as well as from the stripping of soil and rocks that are predominately composed of iron minerals, necessitating further management such as aeration. All study sites' Mn (manganese) parameters continue to fall short of the quality requirements outlined in No. Minister of Health Regulation 416 of 1990 Requirements on water quality No. Minister of Health Regulation 416 of 1990 Requirements on water quality and monitoring, that is, always exceeding the quality standard by 0.5 mg\/L, except for stations 4, 5 and 6 There are 3 locations of Mn (manganese). In general, it can be concluded that the Fe and pH parameters of the study area still do not meet the freshwater quality standards. While Mn partially meets freshwater quality standards atstations (4, 5 and 6). Stations 1, 2, 3, 7, 9 are always higher than fresh water quality standards. The problem of acid mine drainage requires environmentally friendly water treatment.<\/jats:p>","DOI":"10.1051\/bioconf\/20236902008","type":"journal-article","created":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T07:57:07Z","timestamp":1697443027000},"page":"02008","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of Iron (Fe), Manganese (Mn), and pH of Coal Mine Acidic Water in Aceh Province"],"prefix":"10.1051","volume":"69","author":[{"family":"Kiswanto","sequence":"first","affiliation":[]},{"family":"Wintah","sequence":"additional","affiliation":[]}],"member":"250","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"issue":"3","key":"R1","first-page":"1","volume":"29","author":"Kiswanto","year":"2023","journal-title":"Jurnal Teknik Lingkungan (JTL)"},{"key":"R2","doi-asserted-by":"crossref","first-page":"305030","DOI":"10.1051\/e3sconf\/20187303020","volume":"73","author":"Susanto","year":"2018","journal-title":"E3s Web Of Conferences"},{"key":"R3","unstructured":"Susanto H., Sudarno , and Kiswanto , \u201cKarakteristik Air Asam Batubara Di Kolam Bekas Tambang Batubara Pt. 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